A comprehensive and practical reference on radiation protection. Describes radiation basics, external and internal dosimetry and biological effects of ionizing radiation. Demonstrates the fundamentals and calculations as they are applied to various health physics fields. Over 375 worked examples, presented within the context of diverse scenarios, aid readers in testing their knowledge as well as applying the concepts to actual situations.
Essential Forensic Biology is an introduction to the application of the science of biology in legal investigations. Focusing on the legal system in the UK, the book provides a detailed description of the decay process, and discusses the role of forensic indicators – human fluids and tissues, including blood cells, bloodstain pattern analysis, hair, teeth, bones and wounds. It also considers the role microorganisms, invertebrates and plants play within forensic investigations before considering future directions in forensic science. The book examines the study of forensic biology in cases of suspicious death, and also explores the organisms used in a range of legal investigations; from human and animal neglect to food spoilage, structural damage, the illegal collection/trade of protected species and bioterrorism. Essential Forensic Biology fills the gap for a resource, which provides information on the range of biological organisms; animals, plants and microbes used in forensic studies. An invaluable introductory text for all students taking forensic science courses, the book features a fully integrated website that covers forensic entomology with additional material and figures from the text to enhance student understanding. An introduction covering the essentials of forensic biology Features a fully integrated website covering forensic entomology with additional material and self-test questions to reinforce student understanding Each chapter includes a series of questions and topics for further study Focuses on the UK legal system From the reviews: “…the numerous black and white photographs, drawings and tables within the book are clear and well deployed.” TIMES HIGHER EDUCATION SUPPLEMENT, 23rd February 2007
This book meets the long-awaited need for a comprehensive overview of the biological role of HDLs. Edited by one of the pioneers in HDL and cholesterol research, this monograph summarizes current knowledge on HDL turnover, regulation and physiology. Clearly structured, the various sections cover HDL structure, formation, secretion and removal, as well as plasma metabolic factors. The biological activities and clinical aspects are equally discussed, as is the impact of HDL on common diseases and their prevention.
In this first integrated view, practically each of the world's leading experts has contributed to this one and only authoritative resource on the topic. Bringing systems biology to cellular energetics, they address in detail such novel concepts as metabolite channeling and medical aspects of metabolic syndrome and cancer.
A review and discussion of new knowledge on the structure and function of mammalian alkaline phosphatases (APs) gained over the last 25 years. It covers: * The structure, regulation and expression of the AP genes * The three-dimensional structure of APs and mutagenesis work that further defined the structural/functional domains of the isozymes * The phenotypic abnormalities of the different AP knockout mice * Our current understanding of the in vivo role of the AP isozymes. The book also describes the possible use of APs as therapeutic agents and therapeutic targets and the many uses of these enzymes in clinical medicine and in biotechnology.
In 17 contributions by leading research groups, this first comprehensive handbook in the field covers the interactions between proteins and lipids that make the fabric of biological membranes from every angle. It examines the relevant hermodynamic and structural issues from a basic science perspective, and goes on to discuss biochemical and cell biological processes. The book covers physical principles as well as mechanisms of membrane fusion and fission. Additionally, chapters on bilayer structure and protein-lipid interactions as well as on how proteins shape lipids and vice versa, membrane penetration by toxins, protein sorting, and allosteric regulation of signal transduction across membranes make this a valuable information source for researchers in academia and industry.
This book provides basic principles of multivalent interactions found in biological systems as well as an up-to-date and thorough coverage in design concepts, syntheses, and biological activities of multivalent molecules. * Contains practical examples of synthetic multivalent molecules in chemistry, biology, and medicine * Can be used as both a textbook for students and a reference book for libraries and professionals * Includes detailed case studies * Fills a void in current literature through its devotion solely to multivalent molecules
Vanadium is named after Vanadis, the most aristocratic of Norse goddesses, who symbolises beauty and fertility – essential features of vanadium chemistry. It is a ubiquitous trace element, with a surprising range of biological functions. In Bioinorganic Vanadium Chemistry, Dieter Rehder addresses the major aspects of vanadium chemistry related to living organisms and the mutual impact between biological and inorganic vanadium chemistry. Topics covered include: the history, natural occurrence, distribution and impact of vanadium inorganic aspects of the function of vanadium in biological systems interaction of aqueous vanadate and vanadyl with biogenic ligands vanadium coordination compounds the vanadium-carbon bond methods of characterisation of biogenic and model vanadium systems (EPR and ENDOR for oxovanadium(IV); 51V NMR for vanadium(V); XAS) vanadium in ascidians and polychaeta worms the concentration of vanadium in the form of amavadin by Amanita mushrooms vanadate-dependent haloperoxidases vanadium and the nitrogen cycle vanadate as energiser for bacteria, and vanadophores medicinal aspectsm including the anti-diabetic potential of vanadium compounds interaction of vanadium with proteins and protein substrates vanadium and phosphate-metabolising enzymes Bioinorganic Vanadium Chemistry conveys the essential aspects of vanadium bioinorganic chemistry, making this book a valuable complement to more general bioinorganic chemistry texts and more specialized topical reviews for researchers and students alike.
Post Genomics Drug Discovery and Research explores and discusses some of the most important topics in post-genomics life and biopharmaceutical sciences. It provides an introduction to the field, outlining examples of many techniques currently used, as well as those still under development, which are important for the research of biopharmaceutical discovery in the post-genomics era. Integrates several developing and cutting-edge technologies and methods like bioinformatics, experimental therapeutics, and molecular recognition Includes discussion on topics such as: computer-aided ligand design; peptide and protein chemistry and synthesis; synthesis of active natural products; and the use of emerging technologies like proteomics, nanotechnology, or bioengineering.
How can a piano tuner obtain such high precision with no other measuring device than their own ears? How can a sequence of notes seem to rise continuously despite coming back periodically to the same notes? What are the possibilities and the limits of digital sound? These are a few examples of questions that are discussed in this book, which presents an overview on the nature of musical sounds, from their production by acoustic music instruments to synthesized sounds obtained with computers. The topics that are treated include sound propagation, Fourier and time-frequency analysis, psychoacoustics, analog and digital signal processing theory, computer science and MP3 sound compression, and of course… music!