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    Sleep Medicine Essentials

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    Based on the highly acclaimed Sleep: A Comprehensive Handbook, this is a concise, convenient, practical, and affordable handbook on sleep medicine. It consists of forty topic-focused chapters written by a panel of international experts covering a range of topics including insomnia, sleep apnea, narcolepsy, parasomnias, circadian sleep disorders, sleep in the elderly, sleep in children, sleep among women, and sleep in the medical, psychiatric, and neurological disorders. It serves as an effective Sleep Medicine board examination review, and every chapter includes sample boards -style questions for test preparation and practice.

    Ethics for Psychologists

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    Ethics for Psychologists, 2nd Edition is a comprehensive handbook covering the full range of ethical challenges that confront psychologists in practice and research Written for all psychology practitioners and researchers Addresses new concerns such as 'whistleblowing', quantifying ethics, and Internet-related issues Features greatly expanded section of case studies, resolutions, and work exercises Suitable for all English-speaking countries beyond just North America Includes guidance on a variety of national ethics codes, including the European Meta-Code of Ethics and the UN Declaration of Human Rights

    Law for Doctors

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    This is a guide for all doctors – GPs and hospital doctors alike, on the law and how it affects them. It is a practical guide, and it approaches its subject with the use of realistic scenarios throughout. These relevant case histories are used as a basis for discussion and explanation of the legal implications of a doctors actions. Guidelines for best practice are given. This is not a theoretical book. Its aim is to give the reader an understanding of the way in which they may be legally challenged as health professionals, and how to minimize this risk. Unlike many law books, «Law for Doctors» assumes little or no knowledge of law and legal terms.

    Primary Health Care

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    General practitioners and other primary care professionals have a leading role in contemporary health care, which Trisha Greenhalgh explores in this highly praised new text. She provides perceptive and engaging insights into primary health care, focussing on: • its intellectual roots • its impact on the individual, the family and the community • the role of the multidisciplinary team • contemporary topics such as homelessness, ethnic health and electronic records. Concise summaries, highlighted boxes, extensive referencing and a dedicated section on effective learning make this essential reading for postgraduate students, tutors and researchers in primary care. ___ From the foreword by Julian Tudor Hart “Trish Greenhalgh, in her frequent columns in the British Medical Journal…more than any other medical journalist spoke to her fellow GPs in the language of experience, but never without linking this to our expanding knowledge from the whole of human science. When I compare the outlines of primary care so lucidly presented in this wonderful book, obviously derived from rich experience of real teaching and learning, with the grand guignol theatre of London medical schools when I was a student 1947-52, the advance is stunning.” ___ «Trish Greenhalgh is one of the international stars of general practice and a very clever thinker. This new book is a wonderful resource for primary health care and general practice. Every general practice registrar should read this book and so should every general practice teacher and primary care researcher.» Professor Michael Kidd, Head of the Department of General Practice, University of Sydney and Immediate Past President of The Royal Australian College of General Practitioners “This important new book by one of primary care's most accomplished authors sets out clearly the academic basis for further developments in primary health care. Health systems will only function effectively if they recognise the importance of high quality primary care so I strongly recommend this book to students, teachers, researchers, practitioners and policy makers.” Professor Martin Marshall, Deputy Chief Medical Officer, Department of Health, UK

    Autoantibodies and Autoimmunity

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    This is the first book to address all aspects of the biology of autoantibodies in a single volume, including a discussion of immunology, experimental models, clinical aspects, and the use of autoantibodies as probes in molecular and cellular biology. The editor, currently professor at the W.M. Keck Autoimmune Disease Center of The Scripps Research Institute, has assembled an all-star team of authors to report on the latest research, technologies, and applications. Following an introductory chapter, the book goes on to cover such topics as cellular mechanisms of autoantibody production, clinical and diagnostic usefulness in human disease, and animal models used to study the elicitation of autoantibodies. The whole is rounded off with a look at future perspectives. With its comprehensive coverage, this volume will appeal not only to immunologists and clinicians but also to cell and molecular biologists.

    Bioinformatics Software Engineering

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    Bioinformatics Software Engineering: Delivering Effective Applications will be useful to anyone who wants to understand how successful software can be developed in a rapidly changing environment. A handbook, not a textbook, it is not tied to any particular operating system, platform, language, or methodology. Instead it focuses on principles and practices that have been proven in the real world. It is pragmatic, emphasizing the importance of what the author calls Adaptive Programming – doing what works in your situation, and it is concise, covering the whole software development lifecycle in one slim volume. At each stage, it describes common pitfalls, explains how these can be avoided, and suggests simple techniques which make it easier to deliver better solutions. «Well thought-out … addresses many of the key issues facing developers of bioinformatics software.» (Simon Dear, Director, UK Technology and Development, Bioinformatics Engineering and Integration, Genetics Research, GlaxoSmithKline) Here are some examples from the book itself. On software development: “Writing software properly involves talking to people – often lots of people – and plenty of non-coding work on your part. It requires the ability to dream up new solutions to problems so complicated that they are hard to describe.” From description to specification: “Look for verbs – action words, such as ‘does’, ‘is’ and ‘views’. Identify nouns – naming words, like ‘user’, ‘home’ and ‘sequence’. List the adjectives – describing words, for example ‘quick’, ‘simple’ or ‘precise’. The verbs are the functions that must be provided by your application. The nouns define the parameters to those functions, and the adjectives specify the constraint conditions under which your program must operate.” On how to start writing software: “Handle errors. Take in data. Show output. Get going!” On testing: “It may not be physically possible to test every potential combination of situations that could occur as users interact with a program. But one thing that can be done is to test an application at the agreed extremes of its capability: the maximum number of simultaneous users it has to support, the minimum system configuration it must run on, the lowest communication speed it must cope with, and the most complex operations it must perform. If your program can cope with conditions at the edge of its performance envelope, it is less likely to encounter difficulties in dealing with less challenging situations.” On showing early versions of software to users: “It can be hard explaining the software development process to people who are unfamiliar with it. Code that to you is nearly finished is simply not working to them, and seeing their dream in bits on the workbench can be disappointing to customers, especially when they were expecting to be able to take it for a test drive.” On bugs: “If your users find a genuinely reproducible bug in production code, apologize, fix it fast, and then fix the system that allowed it through. And tell your customers what you are doing, and why, so they will be confident that it will not happen again. Everybody makes mistakes. Don’t make the same ones twice.” And one last thought on successful software development: "You have to be a detective, following up clues and examining evidence to discover what has gone wrong and why. And you have to be a politician, underst

    Bioinformatics for Vaccinology

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    “… this book was written from start to finish by one extremely dedicated and erudite individual. The author has done an excellent job of covering the many topics that fall under the umbrella of computational biology for vaccine design, demonstrating an admirable command of subject matter in fields as disparate as object-oriented databases and regulation of T cell response. Simply put, it has just the right breadth and depth, and it reads well. In fact, readability is one of its virtues—making the book enticing and useful, all at once…” Human Vaccines, 2010 «… This book has several strong points. Although there are many textbooks that deal with vaccinology, few attempts have been made to bring together descriptions of vaccines in history, basic bioinformatics, various computational solutions and challenges in vaccinology, detailed experimental methodologies, and cutting-edge technologies… This book may well serve as a first line of reference for all biologists and computer scientists…» –Virology Journal, 2009 Vaccines have probably saved more lives and reduced suffering in a greater number of people than any other medical intervention in human history, succeeding in eradicating smallpox and significantly reducing the mortality and incidence of other diseases. However, with the emergence of diseases such as SARS and the threat of biological warfare, vaccination has once again become a topic of major interest in public health. Vaccinology now has at its disposal an array of post-genomic approaches of great power. None has a more persuasive potential impact than the application of computational informatics to vaccine discovery; the recent expansion in genome data and the parallel increase in cheap computing power have placed the bioinformatics exploration of pathogen genomes centre stage for vaccine researchers. This is the first book to address the area of bioinformatics as applied to rational vaccine design, discussing the ways in which bioinformatics can contribute to improved vaccine development by introducing the subject of harnessing the mathematical and computing power inherent in bioinformatics to the study of vaccinology putting it into a historical and societal context, and exploring the scope of its methods and applications. Bioinformatics for Vaccinology is a one-stop introduction to computational vaccinology. It will be of particular interest to bioinformaticians with an interest in immunology, as well as to immunologists, and other biologists who need to understand how advances in theoretical and computational immunobiology can transform their working practices.

    Human Blood Groups

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    Human Blood Groups is a comprehensive and fully referenced text covering scientific and clinical aspects of red cell surface antigens, including: serology inheritance biochemistry molecular genetics biological functions clinical significance in transfusion medicine Over a century has passed since Landsteiner discovered the human blood groups, making the practice of blood transfusion possible. Yet, in the six years since the first edition of Human Blood Groups was published, new blood groups have been discovered, several blood group genes have been cloned, and the molecular backgrounds of numerous blood group variants have been worked out. All this new information has made the production of a second edition of Human Blood Groups timely. This book is an essential reference source for all those working in the field of blood transfusion and blood banking.

    Stable Isotope Forensics

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    This book provides the first comprehensive, overview and guide to forensic isotope analysis, an exciting new application of stable isotope analytical techniques. Topics are introduced using examples and real-life case studies such as food quality control where isotope analysis has already had a major impact, in terms of consumer protection, These examples illustrate the underlying principles of isotope profiling or fingerprinting. A section comprising actual criminal case work is used to build a bridge between the introduction and the technical section to encourage students to engage with this novel departure for analytical sciences while at the same time providing hands-on examples for the experienced researcher and forensic practitioner to match problems and success stories encountered with the topics discussed in the technical section. What little information is available on the subject in book form so far, has been published as individual chapters in books dealing either with mass spectrometry, forensic geoscience or environmental forensics, this is the first book to focus on the entire spectrum of forensic isotope analysis and will be an invaluable reference to both researchers in the field and forensic practitioners.

    Practical Diabetes Care

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    Concise, affordable and extremely practical, Practical Diabetes Care, 4th edition offers a wholly clinical approach to diabetes and its treatment. Covering all the practical aspects of all major aspects of Type 1 and Type 2 diabetes, it also includes the very latest in clinical research and trial results. Structured in a problem-orientated way, the book focuses on the areas of maximum anxiety for health-professionals treating patients with diabetes, e.g. hyperglycaemic emergencies, and multiple complications. Easy to navigate, clear and convenient for when on the wards and in clinic, this is the perfect guide to the practical aspects of caring for patients with diabetes.