Группа авторов
Список книг автора Группа авторовImmunodominance
This very first handbook on the topic summarizes the current concepts and brings together in one volume the critical arguments concerning the mechanisms relevant to immunodominance. In invited chapters written by the leaders in the field, the mechanisms whereby the immune system chooses the parts of a recognized pathogen in order to start the immune response are explained and the variety of biologic processes are identified that contribute to that choice. From the contents: * Mechanics of antigen processing * Proteosome specificity and immuno-proteosomes * Effect of the T cell repertoire on dominance * Effects of pathogens on the immune response
Gynaecology
This book addresses the reality of delivering gynaecological care in the 21st century, and looks at the developments that are currently taking place in the field. It provides an overview of some common gynaecological problems and looks at new services and different ways of delivering care. It also shows how gynaecological services are developing in response to women's needs. Above all the book is not medically orientated but shows how nurses and professionals allied to medicine are making a difference. * Covers the latest developments in the gynaecological field * Written soecifically from a nursing and allied health professionals perspective
Immunization
Immunization: Childhood and Travel Health provides an all-encompassing reference for all those working in primary care, secondary care paediatric wards, immunization centres and travel clinics, as well as medical students and candidates working for higher examinations. The Fourth Edition has been comprehensively updated and the travel section completely revised. The book gives a thorough introduction to the history of immunization, vaccine technology and immunology, and compares international schedules of routine immunizations. Each vaccine is then presented separately, including contraindications, local and general side and adverse effects, administration advice, special precautions and notes, vaccine availability, storage, and well-referenced comments on issues surrounding each vaccine, including controversies. A description of the infection caused by the relevant microorganisms follows, together with data on disease notifications and immunization coverage. A considerable number of maps illustrate endemicity of diseases. One section is dedicated to issues relevant to primary care such as immunization fees and targets, audit, electronic recall systems, patient group directions and issues surrounding the immunization work of the practice nurse. The Fourth Edition includes an extensive section on travel health, which includes the latest travel statistics, travel clinics, detailed advice to travellers and legal issues that may arise. A considerable amount of information is included on air travel, contraindications to travel, and high altitude sickness. Specific information is given on advising travellers at risk because of pre-existing conditions, and how to best deal with the returned traveller. Advice is provided for each disease, including malaria, which is covered in detail. The last section contains information on notifiable diseases, reciprocal healthcare agreements, contact numbers for Embassies and High Commissions in London, a world travel advice checklist, and an extensive list of sources of travel information with contact address.
Vitiligo
This monograph is a comprehensive expose of the disorder vitiligo. The book introduces the topic with a presentation about its cultural effects in the Middle East where vitiligo is exceptionally disabling to the affected person. Nehru as Prime Minister of India stated that vitiligo was a major impediment to the successful development of India. The book includes sections on the definition of vitiligo based on a consensus of world experts on vitiligo. There is a complete description of its clinical manifestations including the extracutaneous sites by world experts. Differentiation of vitiligo from other forms of depigmentation associated with malignancies is included with sufficient photographs to document differences. A section will present the physiological changes associated with depigmentation – a little known phenomena. The complete histology, differential diagnosis and animal models are major sections. The animal models are important in formulating theories about the causes of vitiligo. Most clinicians will find this section very informative. The book finishes with a thorough treatise on the principles of therapy.
Principles of Assessment and Outcome Measurement for Occupational Therapists and Physiotherapists
This textbook on assessment and outcome measurement is written for both occupational therapy and physiotherapy students and qualified therapists. It begins by defining what is meant by assessment, outcome, evaluation and measurement and discussing the complexity of therapy assessment and measurement, including the challenge of measuring human behaviour and the impact of factors such as task demand and context, including the environment. Methods of data collection (e.g. observation, interview, standardised testing) and sources (e.g. self-report, proxy) for collecting information about clients are then reviewed, and the main purposes of assessment (e.g. descriptive, evaluative, predictive, discriminative) presented. The book then addresses the topics of standardisation, levels of measurement, reliability, validity and clinical utility. There is a chapter describing and applying models for categorizing levels of function to aid assessment and measurement. The concept of clinical reasoning and reflective practice is then explored. Application of principles is supported through detailed case studies and worksheets and the criteria for test critique and guidelines for choosing a particular assessment approach are discussed.
Chemical and Functional Genomic Approaches to Stem Cell Biology and Regenerative Medicine
Scientists believe that stem cells have the potential to revolutionize the treatment of numerous diseases and conditions. This guide covers recent advances in technologies and their applications in stem cell biology, addressing the use of both embryonic and adult stem cells and discussing diverse technologies, including genome-wide expression analysis, informatics, chemical genomics, and more. Applications covered encompass self-renewal, differentiation, reprogramming, and regeneration in model organisms. This is a premier reference for practicing professionals involved in stem cell research and students.
Assessment and Management of Emotional and Psychosocial Reactions to Brain Damage and Aphasia
Aims to provide an accessible and practical guide to the assessment, differentiation and clinical management of the emotional and psychosocial problems of aphasic and non-aphasic brain damaged individuals and their families. Current clinical approaches are also considered.
Neonatal Formulary
The Neonatal Formulary is a unique book providing advice on the safe use of drugs during pregnancy, labour and throughout the first year of life. Thoroughly updated, this fifth edition draws on the experience of an increasingly international group of neonatologists and is now a well established reference on prescribing in infancy. It covers all the drugs commonly used in the perinatal period, including those used for fetal treatment, and summarizes how the prescribing of each has to adapt to changes in drug elimination during the first year of life. Key features for the fifth edition include: fully updated monographs and references 20 full monographs for diseases more commonly seen in the tropics invaluable information on dose sizes and administration for babies further inclusion of evidence from relevant RCTs and systematic reviews from the Cochrane database a free access website with regular updates and links to other useful information. IMPORTANT DOSAGE CHANGE
Nursing Knowledge
Nurses who conduct research have a longstanding interest in questions of nursing knowledge. Nursing Knowledge is a clear and well-informed exposition of the philosophical background to nursing theory and research. Nursing Knowledge answers such fundamental questions as: How is nursing theory related to nursing practice? What are the core elements of nursing knowledge? What makes nursing research distinctive as nursing research? It examines the history of the philosophical debates within nursing, critiques the arguments, explains the implications and sets out to rethink the philosophical foundation of nursing science. Nursing Knowledge begins with philosophical problems that arise within nursing science. It then considers various solutions with the help of philosophical ideas arguingargues that nurses ought to adopt certain philosophical positions because they are the best solutions to the problems that nurses encounter. The book argues claims that the nursing standpoint has the potential to disclose a more complete understanding of human health than the common disease-and-dysfunction views. Because of the relationship to practice, nursing science may freely draw theory from other disciplines and nursing practice unifies nursing research. By redefining theory and philosophy,With a new philosophical perspective on nursing science, the so-called relevance gap between nursing theory and practice can be closed. The final chapter of the book ‘redraws the map’, to create a new picture of nursing science based on the following principles: Problems of practice should guide nursing research Practice and theory are dynamically related Theory research must provide the knowledge base necessary for nurse interventions, training, patient education, etc. Nursing research should develop midrange theories and its results are nursing theory is strengthened when it uses theories confirmed by is integrated with other disciplines Key features Clear and accessibly written Accurate and philosophically well-informed, Discusses philosophical problems in contexts familiar to nurses Systematically examines the philosophical issues involved in nursing research Examines epistemology (how we know what we know), theory development, and the philosophical foundations of scientific methodology. Develops a new model of nursing knowledge Dr. Mark Risjord is Associate Professor in Philosophy at Emory University, and has a faculty appointment in the Nell Hodgson Woodruff School of Nursing. His main research areas have been in the philosophy of social science and the philosophy of medicine. He was invited to has been teaching philosophy of science and theory development in the new PhD program in the Nell Hodgson School of Nursing at Emory University insince 1999. He has been awarded two competitive teaching prizes: Emory Williams Distinguished Teaching Award (2004) and the Excellence in Teaching Award (1997). He is presently serving as the Masse-Martin/NEH Distinguished Teaching Chair (2006-2010).
Pain Management
Conventional pharmaceutical approaches to pain management are not always successful. Using only those medications that have an official indication for a certain condition reduces substantially the chance of the patient gaining pain relief and may expose them to intolerable side effects. However evidence now exists on the use of other drugs, produced for non-pain conditions, and how they can substantially increase the chances of pain relief. Covering the most recent developments in this field, McCleane offers an alternative solution to pain treatment when conventional treatments fail. This pioneering book proposes evidence-based alternatives to current options in pain management, using well-grounded rationales for each given treatment. This book is an ideal reference for the specialist and non-specialist prescriber alike and for practitioners from a wide variety of disciplines. It provides the evidence required and treatment algorithms for readers to use the drugs appropriately and to explore the field if they wish.