Ingram
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Pediatric Ear Diseases
Due to the complex anatomical structure of the temporal bone, imaging diagnosis requires a very high degree of expertise. This atlas is not only helpful to assess pediatric ear disorders accurately, but also provides a treasure trove to experts. It consists of a pediatric temporal bone imaging atlas followed by case reports of typical pediatric ear diseases. In the first part complete contiguous temporal bone CT sections of an infant and an older child are shown along with a detailed listing of anatomical names of the structures. It further presents developmental changes in size, shape, location and orientation of the primary components of the temporal bone. The second part contains case images in combination with reference illustrations of a healthy child in the same age range allowing the reader to identify the key findings of the disorder with only one reference book at hand. Further images illustrate the posttreatment follow-up. This publication which is translated from the successful Japanese edition (2011) will be essential for otorhinolaryngologists and pediatricians particularly interested in pediatric ear diseases. Its unique layout makes it also a very effective tool for students learning image diagnosis.
Guide for Investigator Initiated Trials
For academic medical faculty unfamiliar with national and international regulations, the prospect of initiating and managing a clinical trial can be intimidating. The development of protocols and case report forms, compliance with regulatory requirements, the monitoring of clinical trials as well as the responsibilities of documentation are just some of the tasks the sponsor-investigator is faced with. This book covers the entire spectrum of a clinical trial, reviewing the different stages step by step: financial planning, crucial aspects of trial design, the authorization process and, finally, documentation. Moreover, it contains helpful tips, a practical glossary, instructions and a large number of resources related to the relevant regulations and forms conforming to the ‘International Conference on Harmonization and Good Clinical Practice’. This makes the publication at hand an essential ‘cookbook’ for both academic faculty new to clinical trials as well as seasoned sponsors-investigators.
Paul Klee and His Illness
In 1933 Paul Klee’s work was branded as ‘Entartete Kunst’ (Degenerate Art) by the National Socialists and he was dismissed from his professorial post at the Düsseldorf Academy of Fine Arts. This led him, together with his wife Lily, to return to his ‘real home’ of Bern. Here his avant-garde art was not understood and Klee found himself in unasked for isolation. In 1935 Klee started to suffer from a mysterious disease. The symptoms included changes to the skin and problems with the internal organs. In 1940 Paul Klee died, but it was only 10 years after his death that the illness was actually given the name ‘scleroderma’ in a publication about Klee. However, the diagnosis remained mere conjecture. Since his adolescence, the dermatologist and venereologist Dr. Hans Suter has been fascinated by Paul Klee and his art, and more than 30 years ago this fascination spurred him to commence research into the illness and its influence on the art of Paul Klee’s final years. It was due to Dr. Suter’s meticulous investigations that Klee’s illness could be defined as ‘diffuse systemic sclerosis’. In this book the author assembles his findings and describes the rare and complex disease in a clear and comprehensible way. Further, he empathetically interprets more than 90 of Klee’s late works. The point of view of a dermatologist renders a unique source of information. It provides, on one hand, new insights into everyday medical practices at the University of Bern in the 1930s, which will fascinate doctors and local historians alike. While, on the other hand, art historians and art lovers will be absorbed by the newly discovered links between Paul Klee's work and his illness.
New Concepts for Human Disorders of Sexual Development
In the last few years, impressive research has been done on disorders of sex development (DSD), largely expanding the physiopathology with relevant effects on practice. Thus, management of individuals with DSD requires updated scientific knowledge, integrating basic and clinical information. In addition, doctors involved in the care of individuals with DSD need to develop specific personal skills in communication, ethics, legal issues and the ability to work together in dedicated multidisciplinary teams. National or even international networks are also mandatory to create stringent structures for correctly addressing the care of individuals with DSD and to offer them a better long-term outcome. This special issue of Sexual Development covers several of these hot topics and highlights some aspects of research and management. A special paper from a patient support group has been enclosed to present the opinion of affected people. All the authors have been selected regarding their expertise and documented competencies.
GenEthics and Religion
Human gene and cell technology is a diverse and rapidly evolving field of research. As genes represent the 'blueprint' of an organism, their analysis and manipulation is a challenge to our understanding of human nature. Stem cell research, genetic testing, gene therapy, therapeutic and reproductive cloning – all these fields of application have been raising fundamental ethical and religious-theological questions: When does human life begin? Should human beings be allowed to interfere with natural procreation or to manipulate the genome of their own species? Is genetic engineering tantamount to 'playing God'? Based on the symposium 'GenEthics and Religion' held in Basel, Switzerland in May 2008, this volume examines the role religion can play in establishing ethical guidelines to protect human life in the face of rapid advances in biology and especially gene technology. It does so in a multidisciplinary way with contributions by philosophers, theologians, human geneticists, and several bioethicists representing the Christian, Jewish, Islamic and Buddhist perspectives. The essays illustrating a diversity of views and expressing the problems and self-critical reflectiveness of religious ethicists have been brought up to date and discuss the importance of religious ethics in society’s discourse on gene technology.