Malnutrition among children remains a persistent problem around the world. This publication aims to map the challenges within the global landscape of childhood nutrition and considers the importance of nutrition both prior to conception and in children beyond two years of age. Session I provides an updated picture of malnutrition around the world, the recent progress that has been made in eliminating malnutrition in all its forms and several data limitations to track such progress. The role of milk in early life is covered in session II. The chapters describe different aspects of cow’s milk and the possible role of optimized plant proteins as an alternative to dairy ingredients in treating children with severe acute malnutrition. Session III considers the ramifications of environmental constraints to healthy child growth. The chapters cover the issue of how persistent gut damage and systemic inflammation can precipitate malnutrition as well as the putative effects of alterations in the gut microbiota. This overview of diverse issues is relevant to the epidemiology, biology of nutrition in early life, programmatic implications, and future directions.
Most oral diseases are preventable, yet they remain the most globally common noncommunicable disorders, affecting people throughout their lifetime. Lifestyle, including diet and food choice, is central to the occurrence of oral disease. Nutrition and diet can impact the development and status of the oral cavity as well as the progression of illness. Also, poor oral health can influence the ability to eat and, consequently, to maintain an adequate diet and nutrient balance. This book, consisting of 14 chapters, provides current information on the impact of nutrients (macro- and micro-elements and vitamins) and diet on oral health and vice versa (i.e., the impact of oral health on diet/nutrition). It also reviews possible oral health effects of probiotics as well as relationships between genotype and diet, which are important for determining oral disease risk. This book is a helpful resource for under- and postgraduate students. It will also be useful to dentists and nutritionists/dietitians as they integrate nutrition education into medical practice.
Este libro fue concebido como un recurso accesible y útil para los pediatras e incluso para médicos generales y otros trabajadores de la salud, con el objetivo de proporcionar lineamientos claros de diagnóstico y estrategias de tratamiento. Muchos endocrinólogos experimentados en todo el mundo han contribuido a este libro, muchos de los cuales han viajado y han enseñado ampliamente en países en vías de desarrollo. El libro resultante no tiene la intención de ocupar el lugar de los textos estándar; su objetivo es proporcionar información breve y actualizada sobre las afecciones endocrinas, con énfasis en las posibilidades de diagnóstico y las pruebas analíticas y de imagen más útiles y de bajo costo, así como en el tratamiento más apropiado de acuerdo con la posibilidad que se tiene de utilizar recursos terapéuticos cuando, independientemente de que estén indicados, resulten accesibles. También se proporciona una guía sobre cómo acceder a tecnologías más sofisticadas cuando sea necesario. «La influencia de este libro de texto va mucho más allá del diagnóstico y el tratamiento de las enfermedades endocrinas pediátricas en los países en vías de desarrollo. Apoyará las iniciativas existentes que apuntan a la creación de la capacitación en Endocrinología Pediátrica en entornos donde estas condiciones no se reconocen en gran medida. Servirá como un recurso para la capacitación de enfermeras, dietistas, funcionarios de salud y otros profesionales de la salud que trabajan como aliados de los endocrinólogos pediátricos recién capacitados. Les proporcionará una herramienta para abogar por los niños y adolescentes con enfermedades endocrinas y los ayudará a sensibilizar a los legisladores y a las autoridades locales de salud pública sobre la importancia de proporcionar a los pacientes fármacos simples y relativamente asequibles que figuran en la Lista de medicamentos esenciales para niños de la Organización Mundial de la Salud (OMS) (tales como insulina, hidrocortisona, fludrocortisona, diazóxido y levotiroxina) pero que, a menudo, no están disponibles a nivel local.» Jean-Pierre Chanoine, Profesor Clínico, Hospital de Niños de Columbia Británica y Universidad de Columbia Británica, Vancouver.
Hyperandrogenism profoundly affects women’s lives from lowering self-esteem to changing cognition and affective motivation. The polycystic ovary syndrome (PCOS) is the most common androgen excess disorder worldwide. While it is not the focus of this book, some aspects are discussed. The aim of this book is to improve understanding of androgen excess and its impact on several conditions. Topics include development of adipose tissue in females, insulin sensitivity, congenital adrenal hyperplasia, and Cushing’s disease/syndrome. There is also a discussion of PCOS with emphasis on in utero origins and specific genetic and epigenetic factors. This book provides a wealth of relevant information for every endocrinologist and gynecologist who wants to broaden their knowledge of androgens in various conditions.
Die Peritonealdialyse (PD) ist eine valide Nierenersatztherapie, wenn sie in ein Gesamtversorgungskonzept für Patienten mit terminaler Niereninsuffizienz eingebettet ist. Dennoch hat sich die PD bisher noch nicht als echte Langzeitdialyse-Modalität etabliert. Dieses praktische Handbuch enthält neben praktischen Ratschlägen auch ausführliche Informationen über so gut wie alle klinischen und pathophysiologischen Aspekte der PD in einem einfach zugänglichen Format. Es erklärt die komplexen Zusammenhänge der PD klar und dennoch wissenschaftlich fundiert. Dank seiner handlichen Größe passt es in die Kitteltasche jedes Nephrologen, der auf der Station oder im ambulanten Umfeld mit PD-Patienten zu tun hat. Dieses Buch hilft Nephrologen und in der Nephrologie oder Inneren Medizin tätigen Ärzten, aber auch allen anderen, die an der Versorgung von Patienten mit terminaler Nierenerkrankung beteiligt sind, wie Pflegekräften, Apothekern, Ernährungsberatern, Intensivmedizinern und Medizinstudenten, den wissenschaftlichen Hintergrund der PD zu verstehen.
Diabetic retinopathy (DR), a common microvascular complication, has consistently been shown to be associated with an increased risk of cardiovascular disease (CVD). This book provides complete coverage of DR as a potential marker for CVD in those with diabetes. It succinctly reviews the epidemiological and pathogenic links of DR to various cardiovascular events including stroke, coronary artery disease, chronic kidney disease, heart failure, and mortality. Furthermore, it discusses the usefulness of DR in CVD risk prediction and cardiovascular safety of anti-VEGF therapy in diabetic patients. There are insights from contemporary diabetic trials that demonstrated the enhanced cardiovascular benefit of novel glucose lowering therapy. It also highlights the potential of novel retinal imaging to predict CVD and its risk factors using the state-of-the art artificial intelligence-based deep learning systems. This book will be an invaluable resource for specialists translating research findings into clinical care, including those in cardiology, endocrinology, ophthalmology, and general practitioners. IT will also be of interest to public health practitioners, researchers, graduate students, and biotech companies interested in developing retinal image-based diagnostic and prognostic tools.