Treats studies, primarily in human populations, that show casual effects of certain agents, procedures, treatment or programs. Deals with the difficulties that comparative observational studies have because of bias in their design and analysis. Systematically considers the many sources of bias and discusses how care in matching or adjustment of results can reduce the effects of bias in these investigations.
Explains the concepts and use of univariate Box-Jenkins/ARIMA analysis and forecasting through 15 case studies. Cases show how to build good ARIMA models in a step-by-step manner using real data. Also includes examples of model misspecification. Provides guidance to alternative models and discusses reasons for choosing one over another.
This book provides the first simultaneous coverage of the statistical aspects of simulation and Monte Carlo methods, their commonalities and their differences for the solution of a wide spectrum of engineering and scientific problems. It contains standard material usually considered in Monte Carlo simulation as well as new material such as variance reduction techniques, regenerative simulation, and Monte Carlo optimization.
Other volumes in the Wiley Series in Probability and Mathematical Statistics, Ralph A. Bradley, J. Stuart Hunter, David G. Kendall, & Geoffrey S. Watson, Advisory Editors Statistical Models in Applied Science Karl V. Bury Of direct interest to engineers and applied scientists, this book presents general principles of statistics and specific distribution methods and models. Prominent distribution properties and methods that are useful over a wide range of applications are covered in detail. The strengths and weaknesses of the distributional models are fully described, giving the reader a firm, intuitive approach to the selection of the model most appropriate to the problem at hand. 1975 656 pp. Fitting Equations To Data Computer Analysis of Multifactor Data for Scientists and Engineers Cuthbert Daniel & Fred S. Wood With the assistance of John W. Gorman The purpose of this book is to help the serious data analyst, scientist, or engineer with a computer to: recognize the strengths and limitations of his data; test the assumptions implicit in the least squares methods used to fit the data; select appropriate forms of the variables; judge which combinations of variables are most influential; and state the conditions under which the fitted equations are applicable. Throughout, mathematics is kept at the level of college algebra. 1971 342 pp. Methods for Statistical Analysis of Reliability And Life Data Nancy R. Mann, Ray E. Schafer & Nozer D. Singpurwalla This book introduces failure models commonly used in reliability analysis, and presents the most useful methods for analyzing the life data of these models. Highlights include: material on accelerated life testing; a comprehensive treatment of estimation and hypothesis testing; a critical survey of methods for system-reliability confidence bonds; and methods for simulation of life data and for testing fit. 1974 564 pp.
C. R. Rao would be found in almost any statistician's list of five outstanding workers in the world of Mathematical Statistics today. His book represents a comprehensive account of the main body of results that comprise modern statistical theory. -W. G. Cochran «[C. R. Rao is] one of the pioneers who laid the foundations of statistics which grew from ad hoc origins into a firmly grounded mathematical science.» -B. Efrom Translated into six major languages of the world, C. R. Rao's Linear Statistical Inference and Its Applications is one of the foremost works in statistical inference in the literature. Incorporating the important developments in the subject that have taken place in the last three decades, this paperback reprint of his classic work on statistical inference remains highly applicable to statistical analysis. Presenting the theory and techniques of statistical inference in a logically integrated and practical form, it covers: * The algebra of vectors and matrices * Probability theory, tools, and techniques * Continuous probability models * The theory of least squares and the analysis of variance * Criteria and methods of estimation * Large sample theory and methods * The theory of statistical inference * Multivariate normal distribution Written for the student and professional with a basic knowledge of statistics, this practical paperback edition gives this industry standard new life as a key resource for practicing statisticians and statisticians-in-training.
This concise, yet thorough, book is enhanced with simulations and graphs to build the intuition of readers Models for Probability and Statistical Inference was written over a five-year period and serves as a comprehensive treatment of the fundamentals of probability and statistical inference. With detailed theoretical coverage found throughout the book, readers acquire the fundamentals needed to advance to more specialized topics, such as sampling, linear models, design of experiments, statistical computing, survival analysis, and bootstrapping. Ideal as a textbook for a two-semester sequence on probability and statistical inference, early chapters provide coverage on probability and include discussions of: discrete models and random variables; discrete distributions including binomial, hypergeometric, geometric, and Poisson; continuous, normal, gamma, and conditional distributions; and limit theory. Since limit theory is usually the most difficult topic for readers to master, the author thoroughly discusses modes of convergence of sequences of random variables, with special attention to convergence in distribution. The second half of the book addresses statistical inference, beginning with a discussion on point estimation and followed by coverage of consistency and confidence intervals. Further areas of exploration include: distributions defined in terms of the multivariate normal, chi-square, t, and F (central and non-central); the one- and two-sample Wilcoxon test, together with methods of estimation based on both; linear models with a linear space-projection approach; and logistic regression. Each section contains a set of problems ranging in difficulty from simple to more complex, and selected answers as well as proofs to almost all statements are provided. An abundant amount of figures in addition to helpful simulations and graphs produced by the statistical package S-Plus(r) are included to help build the intuition of readers.
A valuable new edition of the trusted, practical guide to managing data in clinical trials Regardless of size, type, or complexity, accurate results for any clinical trial are ultimately determined by the quality of the collected data. Management of Data in Clinical Trials, Second Edition explores data management and trial organization as the keys to developing an accurate and reliable clinical trial. With a focus on the traditional aspects of data collection as well as recent advances in technology, this new edition provides a complete and accessible guide to the management structure of a clinical trial, from planning and development to design and analysis. Practical approaches that result in the collection of complete and timely data are also provided. While maintaining a comprehensive overview of the knowledge and tools that are essential for the organization of a modern clinical trial, the author has expanded the topical coverage in the Second Edition to reflect the possible uses of recent advances in technology in the data collection process. In addition, the Second Edition discusses the impact of international regulations governing the conduct of clinical trials and provides guidelines on ensuring compliance with national requirements. Newly featured topics include: The growing availability of «off-the-shelf» solutions for clinical trials Potential models for collaboration in the conduct of clinical trials between academia and the pharmaceutical industry The increasing use of the Internet in the collection of data and management of trials Regulatory requirements worldwide and compliance with the ICH Good Clinical Practice (GCP) Guidelines Development of Standard Operating Procedures for the conduct of clinical trials Complete with chapter summaries that reinforce key points as well as over one hundred examples, Management of Data in Clinical Trials, Second Edition is an ideal resource for practitioners in the clinical research community who are involved in the development of clinical trials, including data managers, research associates, data coordinators, physicians, and statisticians. This book also serves as an excellent supplemental text for courses in clinical trials at both the undergraduate and graduate levels.
The most thorough and up-to-date introduction to data mining techniques using SAS Enterprise Miner. The Sample, Explore, Modify, Model, and Assess (SEMMA) methodology of SAS Enterprise Miner is an extremely valuable analytical tool for making critical business and marketing decisions. Until now, there has been no single, authoritative book that explores every node relationship and pattern that is a part of the Enterprise Miner software with regard to SEMMA design and data mining analysis. Data Mining Using SAS Enterprise Miner introduces readers to a wide variety of data mining techniques and explains the purpose of-and reasoning behind-every node that is a part of the Enterprise Miner software. Each chapter begins with a short introduction to the assortment of statistics that is generated from the various nodes in SAS Enterprise Miner v4.3, followed by detailed explanations of configuration settings that are located within each node. Features of the book include: The exploration of node relationships and patterns using data from an assortment of computations, charts, and graphs commonly used in SAS procedures A step-by-step approach to each node discussion, along with an assortment of illustrations that acquaint the reader with the SAS Enterprise Miner working environment Descriptive detail of the powerful Score node and associated SAS code, which showcases the important of managing, editing, executing, and creating custom-designed Score code for the benefit of fair and comprehensive business decision-making Complete coverage of the wide variety of statistical techniques that can be performed using the SEMMA nodes An accompanying Web site that provides downloadable Score code, training code, and data sets for further implementation, manipulation, and interpretation as well as SAS/IML software programming code This book is a well-crafted study guide on the various methods employed to randomly sample, partition, graph, transform, filter, impute, replace, cluster, and process data as well as interactively group and iteratively process data while performing a wide variety of modeling techniques within the process flow of the SAS Enterprise Miner software. Data Mining Using SAS Enterprise Miner is suitable as a supplemental text for advanced undergraduate and graduate students of statistics and computer science and is also an invaluable, all-encompassing guide to data mining for novice statisticians and experts alike.
A unique synthesis of the three existing Fourier-analytic treatments of quadratic reciprocity. The relative quadratic case was first settled by Hecke in 1923, then recast by Weil in 1964 into the language of unitary group representations. The analytic proof of the general n-th order case is still an open problem today, going back to the end of Hecke's famous treatise of 1923. The Fourier-Analytic Proof of Quadratic Reciprocity provides number theorists interested in analytic methods applied to reciprocity laws with a unique opportunity to explore the works of Hecke, Weil, and Kubota. This work brings together for the first time in a single volume the three existing formulations of the Fourier-analytic proof of quadratic reciprocity. It shows how Weil's groundbreaking representation-theoretic treatment is in fact equivalent to Hecke's classical approach, then goes a step further, presenting Kubota's algebraic reformulation of the Hecke-Weil proof. Extensive commutative diagrams for comparing the Weil and Kubota architectures are also featured. The author clearly demonstrates the value of the analytic approach, incorporating some of the most powerful tools of modern number theory, including adèles, metaplectric groups, and representations. Finally, he points out that the critical common factor among the three proofs is Poisson summation, whose generalization may ultimately provide the resolution for Hecke's open problem.
The first comprehensive survey of mathematics' most fascinating number sequences Fibonacci and Lucas numbers have intrigued amateur and professional mathematicians for centuries. This volume represents the first attempt to compile a definitive history and authoritative analysis of these famous integer sequences, complete with a wealth of exciting applications, enlightening examples, and fun exercises that offer numerous opportunities for exploration and experimentation. The author has assembled a myriad of fascinating properties of both Fibonacci and Lucas numbers-as developed by a wide range of sources-and catalogued their applications in a multitude of widely varied disciplines such as art, stock market investing, engineering, and neurophysiology. Most of the engaging and delightful material here is easily accessible to college and even high school students, though advanced material is included to challenge more sophisticated Fibonacci enthusiasts. A historical survey of the development of Fibonacci and Lucas numbers, biographical sketches of intriguing personalities involved in developing the subject, and illustrative examples round out this thorough and amusing survey. Most chapters conclude with numeric and theoretical exercises that do not rely on long and tedious proofs of theorems. Highlights include: * Balanced blend of theory and real-world applications * Excellent reference material for student reports and projects * User-friendly, informal, and entertaining writing style * Historical interjections and short biographies that add a richer perspective to the topic * Reference sections providing important symbols, problem solutions, and fundamental properties from the theory of numbers and matrices Fibonacci and Lucas Numbers with Applications provides mathematicians with a wealth of reference material in one convenient volume and presents an in-depth and entertaining resource for enthusiasts at every level and from any background.