Basic Virology. Martinez J. Hewlett

QUESTIONS FOR CHAPTER 21 Problems PART IV Additional Reading for Part IV VIRUS RESOURCES ON THE INTERNET

      14  PART V: Molecular Genetics of Viruses CHAPTER 22: The Molecular Genetics of Viruses MUTATIONS IN GENES AND RESULTING CHANGES TO PROTEINS ANALYSIS OF MUTATIONS ISOLATION OF MUTANTS A TOOL KIT FOR MOLECULAR VIROLOGISTS LOCATING SITES OF RESTRICTION ENDONUCLEASE CLEAVAGE ON THE VIRAL GENOME – RESTRICTION MAPPING CLONING VECTORS DIRECTED MUTAGENESIS OF VIRAL GENES GENERATION OF RECOMBINANT VIRUSES QUESTIONS FOR CHAPTER 22 CHAPTER 23: Molecular Pathogenesis AN INTRODUCTION TO THE STUDY OF VIRAL PATHOGENESIS ANIMAL MODELS METHODS FOR THE STUDY OF PATHOGENESIS CHARACTERIZATION OF THE HOST RESPONSE QUESTIONS FOR CHAPTER 23 CHAPTER 24: Viral Bioinformatics BIOINFORMATICS BIOLOGICAL DATABASES BIOLOGICAL APPLICATIONS SYSTEMS BIOLOGY AND VIRUSES VIRAL INTERNET RESOURCES QUESTIONS FOR CHAPTER 24 CHAPTER 25: Viruses and the Future – Problems and Promises CLOUDS ON THE HORIZON – EMERGING DISEASE WHAT ARE THE PROSPECTS OF USING MEDICAL TECHNOLOGY TO ELIMINATE SPECIFIC VIRAL AND OTHER INFECTIOUS DISEASES? SILVER LININGS – VIRUSES AS THERAPEUTIC AGENTS WHY STUDY VIROLOGY? QUESTIONS FOR CHAPTER 25 Problems PART V Additional Reading for Part V

      15  Appendix – Resource Center BOOKS OF HISTORICAL AND BASIC VALUE BOOKS ON VIROLOGY MOLECULAR BIOLOGY AND BIOCHEMISTRY TEXTS DETAILED SOURCES SOURCES FOR EXPERIMENTAL PROTOCOLS THE INTERNET

      16  Technical Glossary

      17  Index

      18  End User License Agreement

      List of Tables

      1 Chapter 2Table 2.1 Some viruses that replicate in cells of the immune system.Table 2.2 Some examples of viral cytopathic effect.

      2 Chapter 3Table 3.1 Some pathogenic viruses, their vectors or routes of spread, and the...

      3 Chapter 4Table 4.1 Some viruses infecting humans.

      4 Chapter 5Table 5.1 Classification of viruses according to the ICTV.Table 5.2 The Baltimore classification scheme for viruses.

      5 Chapter 6Table 6.1 Some cellular receptors for selected animal viruses.Table 6.2 SomeE. coli bacteriophage receptors.

      6 Chapter 7Table 7.1 Some antiviral proteins induced or activated by interferon.

      7 Chapter 8Table 8.1 Some human viral vaccines.Table 8.2 Some targets for antiviral drugs.

      8 Chapter 10Table 10.1 An example of a set of dilutions for a plaque assay.Table 10.2 An example of a quantal assay for virus infectivity.

      9 Chapter 11Table 11.1 Gel fractionation of the poliovirus’s four capsid proteins.Table 11.2 Protein composition of the HSV‐1 capsid.

      10 Chapter 14Table 14.1 Genomic structure of some positive‐sense RNA viruses infecting euk...

      11 Chapter 15Table 15.1 Similarities and differences of orthomyxovirus and paramyxovirus.Table 15.2 Some members of the Bunyavirales and their vectors.

      12 Chapter 17Table 17.1 Some genetic functions encoded by herpes simplex virus type 1.

      13 Chapter 19Table 19.1 Selected examples of oncogenes acquired by retroviruses.Table 19.2 Bacterial transposons.Table 19.3 Some retroelements of eukaryotic cells.

      14 Chapter 20Table 20.1 Table of lentiviruses showing host species.

      15 Chapter 22Table 22.1 Some viral vector systems.

      16 Chapter 23Table 23.1 Differences in neuroinvasiveness of HSV‐1 strains.Table 23.2 Differences in susceptibility of mouse strains to HSV‐1 infection.

      List of Illustrations

      1 Chapter 1Figure 1.1 A phylogenetic tree of selected species from the three domains of...Figure 1.2 A phylogenetic tree of selected