The recent identification of susceptibility genes for schizophrenia, depression and learning and memory dysfunction suggest that psychiatric disorders may be influenced by a small number of genes with multiple actions. This is the first book to investigate the role of growth factors in these disorders, which should provide clues to the underlying biochemical mechanisms. For example, recent studies have substantiated the provocative finding that neuregulin 1 (NRG1)is a candidate gene for schizophrenia. Neuregulin and its receptors, the ErbB tyrosine kinases, are essential for development of the cardiovascular and nervous systems. Lack of NRG1 function may be involved in dysregulation of synaptogenesis and synaptic plasticity in the adult mediated through glutamate receptor function. Polymorphisms for BDNF (brain-derived neurotrophic factor) have also been implicated in the pathogenesis of schizophrenia. BDNF is a prevalent neurotrophic factor that plays an important role in the pathophysiology of depression, bipolar disease and other psychiatric disorders. Other topics addressed in this book include neuroplasticity and neurotrophic factors, signal transduction by neurotrophins, intracellular trafficking of growth factors, trophic factors and cognitive functions, neurotrophins and depression, and pharmacological treatments of schizophrenia.
A key text for Psychiatrists, psychologists, psychotherapists, as well as trainees in the area. Presenting a clinical model which has close connections with American constructivist psychotherapy and Bowlby’s Attachment Theory. Delineates a set of principles in the study of consciousness that place the first-person perspective at the heart of the analysis of emotional disorders Differentiates six personality styles, describing the origin of the subjective emotional experience; the ordering and the regulation of the emotional domain, and the psychopathological disorders Provides neuroscientific evidence showing that brain activity could be related to personality styles Praise for Selfhood, Identity and Personality Styles: “Arciero and Bondolfi show in fine detail how the sense of self emerges in first- and second-person experiences, forming a dynamic, emotive and narrative identity; they then brilliantly demonstrate how this self-identity gets distorted and disrupted in the pathologies that directly undermine this process. This is a landmark study that brings together materials from multiple disciplines. Their analysis provides a clear account of how our existential being-in-the-world is modulated by narrative practices. They show how the ongoing construction of personality delineated by the various emotional tendencies that are sedimented in the individual’s life comes to be reflected in personal narrative. Arciero and Bondolfi continuously make insightful connections between research in developmental psychology, neuroscience, and emotion studies and then carry these basic insights into the realm of psychiatry. The psychiatric analyses offered here are thus enriched by clinical vignettes and enlightened by the integration of philosophical (especially phenomenological and hermeneutical), psychological, neuroscientific, and literary dimensions”. Shaun Gallagher, Professor of Philosophy, University of Central Florida “Arciero and Bondolfi have written a timely, thought-provoking and challenging book, providing the reader with a refreshingly new account of Self-identity and its disorders. A cogent and novel contribution to psychiatric thought that wonderfully integrates philosophy, psychopathology and contemporary neuroscience. This book will push psychiatry in new directions. A must read!.” Vittorio Gallese, Professor of Human Physiology, University of Parma ,Italy “Selfhood, Identity, and Personality Styles is a highly ambitious work of theoretical synthesis: neuroscience, phenomenology, and social constructionism are joined together with the study of both literature and psychopathology. Arciero and Bondolfi offer sophisticated and intriguing discussions not only of mirror neurons and developmental psychology, but also of ideas from Aristotle, Kant, and Heidegger, of characters from Dostoevsky, Kleist, and Pessoa, and of patients from clinical practice. A ground-breaking, first attempt to show the relevance of the interdisciplinary study of basic self-experience for our understanding of character styles and personality disorders.” Louis A. Sass, Professor of Clinical Psychology, Rutgers University “This is a scholarly book which will provide the reader with plenty to chew on. This book will make you think, will illuminate how people function and will help you understand how self disordered experience, such as the feeling that one disappears or doesn’t exist when another leaves, occurs. The authors tackle with great sophistication, the big questions of how sameness, changing experience and temporality are woven together by language and narrative. Refusing to be reduced to the simplicity of objectivist account of functioning they o
Service user involvement in mental health research poses specific challenges for both researchers and service users. The book describes the relevant background and principles underlying the concept of service user involvement in mental health research, providing relevant practical advice on how to engage with service users and how to build and maintain research collaboration on a professional level. It highlights common practical problems in service user involvement, based on experience from various countries with different social policies and suggests ways to avoid pitfalls and common difficulties. The book helps researchers decide which level of service user involvement will be adequate for their research activities and what will be feasible in view of the practicalities involved. It is also ideal for service users who are interested in becoming involved in research, providing relevant background information on the possibilities of involvement in professional research.
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
Mental health concerns are the most serious and prevalent health problems among students in higher education. Increasingly effective psychopharmacological and psychotherapeutic treatments have facilitated matriculation for students with histories of anxiety, mood, personality, eating and substance abuse disorders. This phenomenon has been accompanied by a striking increase in the number of previously undiagnosed students requesting treatment. College and university mental health programs struggle to care for larger numbers of students, necessitating greater interdisciplinary collaboration in treatment, research, outreach, and educational services. This book fills an important gap in the literature and provides a comprehensive resource for nearly every aspect of college mental health. It includes a strong emphasis on the training and education of graduate and professional students for future work in this field. Chapters are devoted to the significant ethical and legal issues related to treatment and associated administrative and policy challenges. Scholarly chapters on the promise of community mental health and public health approaches are especially innovative. There is also a chapter on international issues in college mental health which will be helpful to those students studying abroad. Mental Health Care in the College Community is written by acknowledged experts from mental health, college and university administration, legal and educational disciplines, all with extensive administrative and clinical experience in higher education settings. This book is clearly written and well illustrated with abundant tables, charts, and figures. This text will become essential reading for college mental health clinicians, graduate students in the mental health disciplines (psychiatry, psychology, counselling, nursing, and social work), student affairs deans and their staff, and even presidents or provosts of universities and colleges.
Hughes' Outline of Psychiatry, Fifth Edition presents a comprehensive account of current practice in psychiatry, summarising up-to-date knowledge of the subject in a concise way. Part I touches on general classification, causes and prevention of mental disorders. It also outlines the basics of the psychiatric interview, examination and investigation. Part II gives an overview of the most common clinical syndromes, covering frequency, epidemiology, causes, clinical features, clinical types, diagnostic criteria, differential diagnosis and treatment for each disorder. Part III focuses on all different treatment options, from Psychological Treatment to Psychosurgery. Fully up-to-date in respect to drugs and treatments, classification systems, and recent legal developments Concentrates on practical clinical techniques rather than psychiatric theory Includes plenty of case studies Format ideal for quick reference or revision This new edition of a well-established and well-received book is an invaluable textbook for medical and psychology students, trainees and psychologists. It is also a helpful resource for mental health nurses, professionals working in health service management and occupational therapy, general practitioners, and other non-specialists who need grounding in all practical aspects of mental health care. From the reviews of the previous edition: “The chapters are well structured, maintaining a balance between remaining comprehensive and interesting. The addition of illustrative case histories is welcome… a highly recommended text” JOURNAL OF SOCIAL PSYCHIATRY “…very easy to read and the general layout is excellent… useful as a quick summary…” THE BRITISH JOURNAL OF PSYCHIATRY
Cigarette smoking is estimated to lead to 4.9 million premature deaths per year worldwide. This is predicted to rise to 10 million by 2020. In western countries it kills half of all smokers who fail to stop. The prevailing model for tobacco addiction is that nicotine from cigarettes rewards smoking and punishes abstinence, tapping into a motivational system of operant conditioning that requires no conscious awareness. However, there are also accounts which involve cognitive biases and the effect of nicotine on impulse control. The brain pathways involved have been studied extensively, but the role of different nicotine receptor subtypes and other neurotransmitter systems is still subject to debate. In western countries, cigarette smoking as an adult has a heritability of 30-50% and candidate genes have been identified that may contribute in part to addiction susceptibility. Many socio-cultural correlates of cigarette smoking have been established, but a comprehensive model that accounts for these and links them with the psychobiological aspects of nicotine addiction has not been forthcoming. Structured behavioural support programmes aid cessation attempts, as do a number of pharmacotherapies, most notably nicotine replacement treatments and bupropion, but the underlying mechanisms are unclear. This book deals with the problems involved in understanding and treating nicotine and tobacco addiction. Topics covered include the nature of the worldwide health problem posed by cigarette smoking, the psychodynamics of cigarette addiction, and the basic pharmacology and biochemistry of nicotine and its effect on the brain. Further chapters analyse the genetic basis of susceptibility to nicotine addiction. Finally, the contributors address approaches to therapy. A continuing theme in the discussions throughout the book is how best to treat nicotine addiction, given that many smokers would like to stop smoking but are unable to do so because of their addiction. This book will be of great value to all psychologists and psychiatrists working on addiction, specifically to nicotine but also to other compounds and behaviours. It will also be of interest to neuroscientists and pharmacologists working on nicotine receptors and the brain pathways involved in dependence, as well as to biochemists, molecular biologist and to public health officials.
Vocational Rehabilitation and Mental Health is a practical guide for all members of the healthcare team to implementing effective services leading to sustained career development among people with mental illness. It examines the barriers to employment such as stigma, discrimination and fluctuating health and discusses the evidence underpinning the provision of effective employment services. The book goes on to examine some of the challenges with implementing evidence-based practice and discusses ways to overcome these challenges.
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.