The physical properties of ultrasound, particularly its highly directional beam behaviour, and its complex interactions with human tissues, have led to its becoming a vitally important tool in both investigative and interventional medicine, and one that still has much exciting potential. This new edition of a well-received book treats the phenomenon of ultrasound in the context of medical and biological applications, systematically discussing fundamental physical principles and concepts. Rather than focusing on earlier treatments, based largely on the simplifications of geometrical acoustics, this book examines concepts of wave acoustics, introducing them in the very first chapter. Practical implications of these concepts are explored, first the generation and nature of acoustic fields, and then their formal descriptions and measurement. Real tissues attenuate and scatter ultrasound in ways that have interesting relationships to their physical chemistry, and the book includes coverage of these topics. Physical Principles of Medical Ultrasonics also includes critical accounts and discussions of the wide variety of diagnostic and investigative applications of ultrasound that are now becoming available in medicine and biology. The book also encompasses the biophysics of ultrasound, its practical applications to therapeutic and surgical objectives, and its implications in questions of hazards to both patient and operator.
This book brings together key features of the toxicology and occupational hazards of pesticides and the way their use is regulated in the main trading regions of the world. There are chapters on each of the main groups of insecticides, namely organochlorines, anticholinesterases and pyrethrins and pyrethroids. The book also covers fungicides and herbicides, as well as more specialised agents such as microbial pesticides. The risks and hazards to humans are considered, both occupational and through the consumption of contaminated foodstuffs. Additionally, clinical aspects of pesticide poisoning are discussed. The possibility of harm from pesticide exposure has led to the development of national and international regulations governing the application of pesticides. The book describes the regulatory systems in three major economic areas: the North American Free Trade Area (USA, Canada and Mexico), the European Union and Japan. This book should be of interest to all individuals working on the development and application of pesticides anywhere in the world. All those involved in the manufacture, regulation and toxicology of pesticides should also benefit from reading this book.
Advanced Life Support Group (ALSG)
This practical book written especially for prehospital staff provides all the information needed to deal with children in life threatening situations before arriving at hospital. It is a complementary volume to the best-selling Advanced Paediatric Life Support
A genuine evidence-based text for optimum pain relief in various chronic conditions Contributes an important advance in the practice of pain management providing the information on which to build more coherent and standardised strategies for relief of patient suffering Answers questions about which are the most effective methods, AND those which are not effective yet continue to be used Includes discussion of the positive and the negative evidence, and addresses the grey areas where evidence is ambivalent Written by the world's leading experts in evidence-based pain management this is a seminal text in the field of pain
A collection of highly valuable statistical and computational approaches designed for developing powerful methods to analyze large-scale high-throughput data derived from studies of complex diseases. Such diseases include cancer and cardiovascular disease, and constitute the major health challenges in industrialized countries. They are characterized by the systems properties of gene networks and their interrelations, instead of individual genes, whose malfunctioning manifests in pathological phenotypes, thus making the analysis of the resulting large data sets particularly challenging. This is why novel approaches are needed to tackle this problem efficiently on a systems level. Written by computational biologists and biostatisticians, this book is an invaluable resource for a large number of researchers working on basic but also applied aspects of biomedical data analysis emphasizing the pathway level.
'Employment Law and Occupational Health: A Practical Handbook' provides an essential guide to best practice for all occupational health practitioners. This readable guide to the law will help to ensure both business success and respect for individual employment rights. The cost of sickness absence can present major costs and business management problems. Safeguarding health is therefore vital to both individuals and employers. 'Employment Law and Occupational Health' explores key issues in occupational health practice from pre-employment, through health surveillance and occupational health services, to termination of employment. Topics explored include ethical and confidentiality issues, discrimination, data protection, working abroad, pregnancy and maternity leave, workplace policies, drugs and alcohol testing, stress, counselling, health surveillance and professional conduct rules. This second edition has been fully revised and updated to include a number of significant changes to employment law as well as new case law decisions that have occurred since the 1st Edition was published. Essential new material has also been included around age discrimination, disability discrimination, work related stress, corporate manslaughter and work-place bullying. An accessible, practical guide to applying health law in everyday practice. For occupational health nurses and other occupational health practitioners. Addresses key employment issues from pre-employment to termination of employment. Includes case studies, procedural checklists, and template letters and forms.
Employment law and occupational health: a practical handbook provides an essential guide to best practice for all occupational health practitioners. This readable guide to the law will help to ensure both business success and respect for individual employment rights. The cost of sickness absence can present major costs and business management problems to employers and safeguarding health is therefore vital to every individual and to all employers. Employment law and occupational health: a practical handbook explores key issues in occupational health practice from pre-employment, through health surveillance and occupational health services to termination of employment. Topics explored include ethical and confidentiality issues, discrimination, data protection, working abroad, pregnancy and maternity leave, workplace policies, drugs and alcohol testing, stress, counselling, health surveillance and professional conduct rules.
Medical Statistics at a Glance is a concise and accessible introduction and revision aid for this complex subject. The self-contained chapters explain the underlying concepts of medical statistics and provide a guide to the most commonly used statistical procedures. This new edition of Medical Statistics at a Glance: Presents key facts accompanied by clear and informative tables and diagrams Focuses on illustrative examples which show statistics in action, with an emphasis on the interpretation of computer data analysis rather than complex hand calculations Includes extensive cross-referencing, a comprehensive glossary of terms and flow-charts to make it easier to choose appropriate tests Now provides the learning objectives for each chapter Includes a new chapter on Developing Prognostic Scores Includes new or expanded material on study management, multi-centre studies, sequential trials, bias and different methods to remove confounding in observational studies, multiple comparisons, ROC curves and checking assumptions in a logistic regression analysis The companion website at www.medstatsaag.com contains supplementary material including an extensive reference list and multiple choice questions (MCQs) with interactive answers for self-assessment. Medical Statistics at a Glance will appeal to all medical students, junior doctors and researchers in biomedical and pharmaceutical disciplines. Reviews of the previous editions «The more familiar I have become with this book, the more I appreciate the clear presentation and unthreatening prose. It is now a valuable companion to my formal statistics course.» –International Journal of Epidemiology «I heartily recommend it, especially to first years, but it's equally appropriate for an intercalated BSc or Postgraduate research. If statistics give you headaches – buy it. If statistics are all you think about – buy it.» –GKT Gazette «…I unreservedly recommend this book to all medical students, especially those that dislike reading reams of text. This is one book that will not sit on your shelf collecting dust once you have graduated and will also function as a reference book.» –4th Year Medical Student, Barts and the London Chronicle, Spring 2003
The new edition adds a chapter on multiple linear regression in biomedical research, with sections including the multiple linear regressions model and least squares; the ANOVA table, parameter estimates, and confidence intervals; partial f-tests; polynomial regression; and analysis of covariance. * Organized by problem rather than method, so it guides readers to the correct technique for solving the problem at hand.
Drug development is the process of finding and producing therapeutically useful pharmaceuticals, turning them into safe and effective medicine, and producing reliable information regarding the appropriate dosage and dosing intervals. With regulatory authorities demanding increasingly higher standards in such developments, statistics has become an intrinsic and critical element in the design and conduct of drug development programmes. Statistical Issues in Drug Development presents an essential and thought provoking guide to the statistical issues and controversies involved in drug development. This highly readable second edition has been updated to include: Comprehensive coverage of the design and interpretation of clinical trials. Expanded sections on missing data, equivalence, meta-analysis and dose finding. An examination of both Bayesian and frequentist methods. A new chapter on pharmacogenomics and expanded coverage of pharmaco-epidemiology and pharmaco-economics. Coverage of the ICH guidelines, in particular ICH E9, Statistical Principles for Clinical Trials. It is hoped that the book will stimulate dialogue between statisticians and life scientists working within the pharmaceutical industry. The accessible and wide-ranging coverage make it essential reading for both statisticians and non-statisticians working in the pharmaceutical industry, regulatory bodies and medical research institutes. There is also much to benefit undergraduate and postgraduate students whose courses include a medical statistics component.