* Considers neoclassical models in light of results that can go wrong with them to bring about better models. * Questions the assumption that markets clear quickly. * Offers a timely examination of the LTCM collapse. * Written by a group of well-respected and highly qualified authors.
The Tutorials in Biostatistics have become a very popular feature of the prestigious Wiley journal, Statistics in Medicine (SIM). The introductory style and practical focus make them accessible to a wide audience including medical practitioners with limited statistical knowledge. This book represents the first of two volumes presenting the best tutorials published in SIM, focusing on statistical methods in clinical studies. Topics include the design and analysis of clinical trials, epidemiology, survival analysis, and data monitoring. Each tutorial is focused on a medical problem, has been fully peer-reviewed and edited, and is authored by leading researchers in biostatistics. Many articles include an appendix on the latest developments since publication in the journal and additional references. This will appeal to statisticians working in medical research, as well as statistically-minded clinicians, biologists, epidemiologists and geneticists. It will also appeal to graduate students of biostatistics.
Incorporates mixed-effects modeling techniques for more powerful and efficient methods This book presents current and effective nonparametric regression techniques for longitudinal data analysis and systematically investigates the incorporation of mixed-effects modeling techniques into various nonparametric regression models. The authors emphasize modeling ideas and inference methodologies, although some theoretical results for the justification of the proposed methods are presented. With its logical structure and organization, beginning with basic principles, the text develops the foundation needed to master advanced principles and applications. Following a brief overview, data examples from biomedical research studies are presented and point to the need for nonparametric regression analysis approaches. Next, the authors review mixed-effects models and nonparametric regression models, which are the two key building blocks of the proposed modeling techniques. The core section of the book consists of four chapters dedicated to the major nonparametric regression methods: local polynomial, regression spline, smoothing spline, and penalized spline. The next two chapters extend these modeling techniques to semiparametric and time varying coefficient models for longitudinal data analysis. The final chapter examines discrete longitudinal data modeling and analysis. Each chapter concludes with a summary that highlights key points and also provides bibliographic notes that point to additional sources for further study. Examples of data analysis from biomedical research are used to illustrate the methodologies contained throughout the book. Technical proofs are presented in separate appendices. With its focus on solving problems, this is an excellent textbook for upper-level undergraduate and graduate courses in longitudinal data analysis. It is also recommended as a reference for biostatisticians and other theoretical and applied research statisticians with an interest in longitudinal data analysis. Not only do readers gain an understanding of the principles of various nonparametric regression methods, but they also gain a practical understanding of how to use the methods to tackle real-world problems.
A hands-on introduction to the tools needed for rigorous and theoretical mathematical reasoning Successfully addressing the frustration many students experience as they make the transition from computational mathematics to advanced calculus and algebraic structures, Theorems, Corollaries, Lemmas, and Methods of Proof equips students with the tools needed to succeed while providing a firm foundation in the axiomatic structure of modern mathematics. This essential book: * Clearly explains the relationship between definitions, conjectures, theorems, corollaries, lemmas, and proofs * Reinforces the foundations of calculus and algebra * Explores how to use both a direct and indirect proof to prove a theorem * Presents the basic properties of real numbers * Discusses how to use mathematical induction to prove a theorem * Identifies the different types of theorems * Explains how to write a clear and understandable proof * Covers the basic structure of modern mathematics and the key components of modern mathematics A complete chapter is dedicated to the different methods of proof such as forward direct proofs, proof by contrapositive, proof by contradiction, mathematical induction, and existence proofs. In addition, the author has supplied many clear and detailed algorithms that outline these proofs. Theorems, Corollaries, Lemmas, and Methods of Proof uniquely introduces scratch work as an indispensable part of the proof process, encouraging students to use scratch work and creative thinking as the first steps in their attempt to prove a theorem. Once their scratch work successfully demonstrates the truth of the theorem, the proof can be written in a clear and concise fashion. The basic structure of modern mathematics is discussed, and each of the key components of modern mathematics is defined. Numerous exercises are included in each chapter, covering a wide range of topics with varied levels of difficulty. Intended as a main text for mathematics courses such as Methods of Proof, Transitions to Advanced Mathematics, and Foundations of Mathematics, the book may also be used as a supplementary textbook in junior- and senior-level courses on advanced calculus, real analysis, and modern algebra.
A timely book on a topic that has witnessed a surge of interest over the last decade, owing in part to several novel applications, most notably in data compression and computational molecular biology. It describes methods employed in average case analysis of algorithms, combining both analytical and probabilistic tools in a single volume. * Tools are illustrated through problems on words with applications to molecular biology, data compression, security, and pattern matching. * Includes chapters on algorithms and data structures on words, probabilistic and analytical models, inclusion-exclusion principles, first and second moment methods, subadditive ergodic theorem and large deviations, elements of information theory, generating functions, complex asymptotic methods, Mellin transform and its applications, and analytic poissonization and depoissonization. * Written by an established researcher with a strong international reputation in the field.
Learn to develop numerical methods for ordinary differential equations General Linear Methods for Ordinary Differential Equations fills a gap in the existing literature by presenting a comprehensive and up-to-date collection of recent advances and developments in the field. This book provides modern coverage of the theory, construction, and implementation of both classical and modern general linear methods for solving ordinary differential equations as they apply to a variety of related areas, including mathematics, applied science, and engineering. The author provides the theoretical foundation for understanding basic concepts and presents a short introduction to ordinary differential equations that encompasses the related concepts of existence and uniqueness theory, stability theory, and stiff differential equations and systems. In addition, a thorough presentation of general linear methods explores relevant subtopics such as pre-consistency, consistency, stage-consistency, zero stability, convergence, order- and stage-order conditions, local discretization error, and linear stability theory. Subsequent chapters feature coverage of: Differential equations and systems Introduction to general linear methods (GLMs) Diagonally implicit multistage integration methods (DIMSIMs) Implementation of DIMSIMs Two-step Runge-Kutta (TSRK) methods Implementation of TSRK methods GLMs with inherent Runge-Kutta stability (IRKS) Implementation of GLMs with IRKS General Linear Methods for Ordinary Differential Equations is an excellent book for courses on numerical ordinary differential equations at the upper-undergraduate and graduate levels. It is also a useful reference for academic and research professionals in the fields of computational and applied mathematics, computational physics, civil and chemical engineering, chemistry, and the life sciences.
This book provides a modern and up-to-date treatment of the Hilbert transform of distributions and the space of periodic distributions. Taking a simple and effective approach to a complex subject, this volume is a first-rate textbook at the graduate level as well as an extremely useful reference for mathematicians, applied scientists, and engineers. The author, a leading authority in the field, shares with the reader many new results from his exhaustive research on the Hilbert transform of Schwartz distributions. He describes in detail how to use the Hilbert transform to solve theoretical and physical problems in a wide range of disciplines; these include aerofoil problems, dispersion relations, high-energy physics, potential theory problems, and others. Innovative at every step, J. N. Pandey provides a new definition for the Hilbert transform of periodic functions, which is especially useful for those working in the area of signal processing for computational purposes. This definition could also form the basis for a unified theory of the Hilbert transform of periodic, as well as nonperiodic, functions. The Hilbert transform and the approximate Hilbert transform of periodic functions are worked out in detail for the first time in book form and can be used to solve Laplace's equation with periodic boundary conditions. Among the many theoretical results proved in this book is a Paley-Wiener type theorem giving the characterization of functions and generalized functions whose Fourier transforms are supported in certain orthants of Rn. Placing a strong emphasis on easy application of theory and techniques, the book generalizes the Hilbert problem in higher dimensions and solves it in function spaces as well as in generalized function spaces. It simplifies the one-dimensional transform of distributions; provides solutions to the distributional Hilbert problems and singular integral equations; and covers the intrinsic definition of the testing function spaces and its topology. The book includes exercises and review material for all major topics, and incorporates classical and distributional problems into the main text. Thorough and accessible, it explores new ways to use this important integral transform, and reinforces its value in both mathematical research and applied science. The Hilbert transform made accessible with many new formulas and definitions Written by today's foremost expert on the Hilbert transform of generalized functions, this combined text and reference covers the Hilbert transform of distributions and the space of periodic distributions. The author provides a consistently accessible treatment of this advanced-level subject and teaches techniques that can be easily applied to theoretical and physical problems encountered by mathematicians, applied scientists, and graduate students in mathematics and engineering. Introducing many new inversion formulas that have been developed and applied by the author and his research associates, the book: * Provides solutions to the distributional Hilbert problem and singular integral equations * Focuses on the Hilbert transform of Schwartz distributions, giving intrinsic definitions of the space H(D) and its topology * Covers the Paley-Wiener theorem and provides many important theoretical results of importance to research mathematicians * Provides the characterization of functions and generalized functions whose Fourier transforms are supported in certain orthants of Rn * Offers a new definition of the Hilbert transform of the periodic function that can be used for computational purposes in signal processing * Develops the theory of the Hilbert transform of periodic distributions and the approximate Hilbert transform of periodic distributions * Provid
A practical guide for multivariate statistical techniques– now updated and revised In recent years, innovations in computer technology and statistical methodologies have dramatically altered the landscape of multivariate data analysis. This new edition of Methods for Statistical Data Analysis of Multivariate Observations explores current multivariate concepts and techniques while retaining the same practical focus of its predecessor. It integrates methods and data-based interpretations relevant to multivariate analysis in a way that addresses real-world problems arising in many areas of interest. Greatly revised and updated, this Second Edition provides helpful examples, graphical orientation, numerous illustrations, and an appendix detailing statistical software, including the S (or Splus) and SAS systems. It also offers * An expanded chapter on cluster analysis that covers advances in pattern recognition * New sections on inputs to clustering algorithms and aids for interpreting the results of cluster analysis * An exploration of some new techniques of summarization and exposure * New graphical methods for assessing the separations among the eigenvalues of a correlation matrix and for comparing sets of eigenvectors * Knowledge gained from advances in robust estimation and distributional models that are slightly broader than the multivariate normal This Second Edition is invaluable for graduate students, applied statisticians, engineers, and scientists wishing to use multivariate techniques in a variety of disciplines.
A unique introduction to the innovative methodology of statistical flowgraphs This book offers a practical, application-based approach to flowgraph models for time-to-event data. It clearly shows how this innovative new methodology can be used to analyze data from semi-Markov processes without prior knowledge of stochastic processes–opening the door to interesting applications in survival analysis and reliability as well as stochastic processes. Unlike other books on multistate time-to-event data, this work emphasizes reliability and not just biostatistics, illustrating each method with medical and engineering examples. It demonstrates how flowgraphs bring together applied probability techniques and combine them with data analysis and statistical methods to answer questions of practical interest. Bayesian methods of data analysis are emphasized. Coverage includes: * Clear instructions on how to model multistate time-to-event data using flowgraph models * An emphasis on computation, real data, and Bayesian methods for problem solving * Real-world examples for analyzing data from stochastic processes * The use of flowgraph models to analyze complex stochastic networks * Exercise sets to reinforce the practical approach of this volume Flowgraph Models for Multistate Time-to-Event Data is an invaluable resource/reference for researchers in biostatistics/survival analysis, systems engineering, and in fields that use stochastic processes, including anthropology, biology, psychology, computer science, and engineering.
A comprehensive account of economic size distributions around the world and throughout the years In the course of the past 100 years, economists and applied statisticians have developed a remarkably diverse variety of income distribution models, yet no single resource convincingly accounts for all of these models, analyzing their strengths and weaknesses, similarities and differences. Statistical Size Distributions in Economics and Actuarial Sciences is the first collection to systematically investigate a wide variety of parametric models that deal with income, wealth, and related notions. Christian Kleiber and Samuel Kotz survey, compliment, compare, and unify all of the disparate models of income distribution, highlighting at times a lack of coordination between them that can result in unnecessary duplication. Considering models from eight languages and all continents, the authors discuss the social and economic implications of each as well as distributions of size of loss in actuarial applications. Specific models covered include: Pareto distributions Lognormal distributions Gamma-type size distributions Beta-type size distributions Miscellaneous size distributions Three appendices provide brief biographies of some of the leading players along with the basic properties of each of the distributions. Actuaries, economists, market researchers, social scientists, and physicists interested in econophysics will find Statistical Size Distributions in Economics and Actuarial Sciences to be a truly one-of-a-kind addition to the professional literature.