Математика
Различные книги в жанре МатематикаIntroductory Biostatistics for the Health Sciences
Accessible to medicine- and/or public policy-related audiences, as well as most statisticians. Emphasis on outliers is discussed by way of detection and treatment. Resampling statistics software is incorporated throughout. Motivating applications are presented in light of honest theory. Plentiful exercises are sprinkled throughout.
Statistical Methods for Rates and Proportions
This book is to be recommended as a standard shelf reference . . . and as a ‘must’ to be read by all who wish to better use and understand data involving dichotomous or dichotomizable measurements. —American Journal of Psychiatry In the two decades since the second edition of Statistical Methods for Rates and Proportions was published, evolving technologies and new methodologies have significantly changed the way today’s statistics are viewed and handled. The explosive development of personal computing and statistical software has facilitated the sophisticated analysis of data, putting capabilities that were once the domain of specialists into the hands of every researcher. The Third Edition of this important text addresses these changes and brings the literature up to date. While the previous edition focused on the use of desktop and handheld calculators, the new edition takes full advantage of modern computing power without losing the elegant simplicity that made the text so popular with students and practitioners alike. In authoritative yet clear terminology, the authors have brought the science of data analysis up to date without compromising its accessibility. Features of the Third Edition include: New material on sample size calculations and issues in clinical trials, and entirely new chapters on single-sample data, logistic regression, Poisson regression, regression models for matched samples, the analysis of correlated binary data, and methods for analyzing fourfold tables with missing data The addition of many new problems, both numerical and theoretical Answer sections for numerical problems and hints for tackling the theoretical ones A frequentist approach enhanced by the inclusion of empirical Bayesian methodology where appropriate Combining the latest research with the original studies that established the previous editions as leaders in the field, Statistical Methods for Rates and Proportions, Third Edition will continue to be an invaluable resource for students, statisticians, biostatisticians, and epidemiologists.
Semiparametric Regression for the Social Sciences
An introductory guide to smoothing techniques, semiparametric estimators, and their related methods, this book describes the methodology via a selection of carefully explained examples and data sets. It also demonstrates the potential of these techniques using detailed empirical examples drawn from the social and political sciences. Each chapter includes exercises and examples and there is a supplementary website containing all the datasets used, as well as computer code, allowing readers to replicate every analysis reported in the book. Includes software for implementing the methods in S-Plus and R.
Statistical Practice in Business and Industry
This book covers all the latest advances, as well as more established methods, in the application of statistical and optimisation methods within modern industry. These include applications from a range of industries that include micro-electronics, chemical, automotive, engineering, food, component assembly, household goods and plastics. Methods range from basic graphical approaches to generalised modelling, from designed experiments to process control. Solutions cover produce and process design, through manufacture to packaging and delivery, from single responses to multivariate problems.
Statistical Analysis of Cost-Effectiveness Data
The statistical analysis of cost-effectiveness data is becoming increasingly important within health and medical research. Statistical Analysis of Cost-Effectiveness Data provides a practical book that synthesises the huge amount of research that has taken place in the area over the last two decades. Comprising an up-to-date overview of the statistical analysis of cost-effectiveness data, the book is supported by numerous worked examples from the author’s own experience. It has been written in a style suitable for medical statisticians and health care professionals alike. Key features include: an overview of statistical methods used in the analysis of cost-effectiveness data. coverage of Bayesian methodology. illustrated throughout by worked examples using real data. suitability for health care professionals with limited statistical knowledge. discussion of software used for data analysis. An essential reference for biostatisticians and health economists engaged in cost-effectiveness analysis of health-care interventions, both in academia and industry. Also of interest to graduate students of biostatistics, public health and economics.
Disease Mapping with WinBUGS and MLwiN
Disease mapping involves the analysis of geo-referenced disease incidence data and has many applications, for example within resource allocation, cluster alarm analysis, and ecological studies. There is a real need amongst public health workers for simpler and more efficient tools for the analysis of geo-referenced disease incidence data. Bayesian and multilevel methods provide the required efficiency, and with the emergence of software packages – such as WinBUGS and MLwiN – are now easy to implement in practice. Provides an introduction to Bayesian and multilevel modelling in disease mapping. Adopts a practical approach, with many detailed worked examples. Includes introductory material on WinBUGS and MLwiN. Discusses three applications in detail – relative risk estimation, focused clustering, and ecological analysis. Suitable for public health workers and epidemiologists with a sound statistical knowledge. Supported by a Website featuring data sets and WinBUGS and MLwiN programs. Disease Mapping with WinBUGS and MLwiN provides a practical introduction to the use of software for disease mapping for researchers, practitioners and graduate students from statistics, public health and epidemiology who analyse disease incidence data.
Cross-over Trials in Clinical Research
Cross-over trials are an important class of design used in the pharmaceutical industry and medical research, and their use continues to grow. Cross-over Trials in Clinical Research, Second Edition has been fully updated to include the latest methodology used in the design and analysis of cross-over trials. It includes more background material, greater coverage of important statistical techniques, including Bayesian methods, and discussion of analysis using a number of statistical software packages. * Comprehensive coverage of the design and analysis of cross-over trials. * Each technique is carefully explained and the mathematics is kept to a minimum. * Features many real and original examples, taken from the author's vast experience. * Includes discussion of analysis using SAS, S-Plus and, GenStat, StatXact and Excel. * Written in a style suitable for statisticians and physicians alike. * Computer programs to accompany the examples in the book can be downloaded from the Web Primarily aimed at statisticians and researchers working in the pharmaceutical industry, the book will also appeal to physicians involved in clinical research and students of medical statistics.
Meta-Analysis of Controlled Clinical Trials
Over the last twenty years there has been a dramatic upsurge in the application of meta-analysis to medical research. This has mainly been due to greater emphasis on evidence-based medicine and the need for reliable summaries of the vast and expanding volume of clinical research. At the same time there have been great strides in the development and refinement of the associated statistical methodology. This book describes the planning, conduct and reporting of a meta-analysis as applied to a series of randomized controlled clinical trials. * The various approaches are presented within a general unified framework. * Meta-analysis techniques are described in detail, from their theoretical development through to practical implementation. * Each topic discussed is supported by detailed worked examples. * A comparison of fixed and random effects approaches is included, as well as a discussion of Bayesian methods and cumulative meta-analysis. * Fully documented programs using standard statistical procedures in SAS are available on the Web. Ideally suited for practising statisticians and statistically-minded medical professionals, the book will also be of use to graduate students of medical statistics. The book is a self-contained and comprehensive account of the subject and an essential purchase for anyone involved in clinical trials.
Data Monitoring Committees in Clinical Trials
There has been substantial growth in the use of data monitoring committees in recent years, by both government agencies and the pharmaceutical industry. This growth has been brought about by increasing recognition of the value of such committees in safeguarding trial participants as well as protecting trial integrity and the validity of conclusions. This very timely book describes the operation of data monitoring committees, and provides an authoritative guide to their establishment, purpose and responsibilities. * Provides a practical overview of data monitoring in clinical trials. * Describes the purpose, responsibilities and operation of data monitoring committees. * Provides directly applicable advice for those managing and conducting clinical trials, and those serving on data monitoring committees. * Gives insight into clinical data monitoring to those sitting on regulatory and ethical committees. * Discusses issues pertinent to those working in clinical trials in both the US and Europe. The practical guidance provided by this book will be of use to professionals working in and/or managing clinical trials, in academic, government and industry settings, particularly medical statisticians, clinicians, trial co-ordinators, and those working in regulatory affairs and bioethics.
Inference and Prediction in Large Dimensions
This book offers a predominantly theoretical coverage of statistical prediction, with some potential applications discussed, when data and/ or parameters belong to a large or infinite dimensional space. It develops the theory of statistical prediction, non-parametric estimation by adaptive projection – with applications to tests of fit and prediction, and theory of linear processes in function spaces with applications to prediction of continuous time processes. This work is in the Wiley-Dunod Series co-published between Dunod (www.dunod.com) and John Wiley and Sons, Ltd.