Группа авторов
Список книг автора Группа авторовBayesian Methods and Ethics in a Clinical Trial Design
How to conduct clinical trials in an ethical and scientifically responsible manner This book presents a methodology for clinical trials that produces improved health outcomes for patients while obtaining sound and unambiguous scientific data. It centers around a real-world test case–involving a treatment for hypertension after open heart surgery–and explains how to use Bayesian methods to accommodate both ethical and scientific imperatives. The book grew out of the direct involvement in the project by a diverse group of experts in medicine, statistics, philosophy, and the law. Not only do they contribute essays on the scientific, technological, legal, and ethical aspects of clinical trials, but they also critique and debate each other's opinions, creating an interesting, personalized text. Bayesian Methods and Ethics in a Clinical Trial Design * Answers commonly raised questions about Bayesian methods * Describes the advantages and disadvantages of this method compared with other methods * Applies current ethical theory to a particular class of design for clinical trials * Discusses issues of informed consent and how to serve a patient's best interest while still obtaining uncontaminated scientific data * Shows how to use Bayesian probabilistic methods to create computer models from elicited prior opinions of medical experts on the best treatment for a type of patient * Contains several chapters on the process, results, and computational aspects of the test case in question * Explores American law and the legal ramifications of using human subjects For statisticians and biostatisticians, and for anyone involved with medicine and public health, this book provides both a practical guide and a unique perspective on the connection between technological developments, human factors, and some of the larger ethical issues of our times.
Ventricular Function and Blood Flow in Congenital Heart Disease
Infants, children and adolescents with congenital heart disease (CHD) are a challenge to manage and an ever-increasing number are reaching adulthood. CHD is one of the most important topics in cardiology today, yet this book is the only clinically-orientated monograph devoted exclusively to ventricular function and blood flow as it relates to CHD. Written by a distinguished panel of cardiologists, bioengineers, physiologists, and clinical investigators, Ventricular Function and Blood Flow in Congenital Heart Disease is an extensive and comprehensive presentation of the key aspects of this branch of CHD.
Color Atlas of Local and Systemic Manifestations of Cardiovascular Disease
This brief guide to visual diagnosis helps the novice develop – and the veteran refresh – crucial skills that can spare the patient unnecessary testing and bring the physician one step closer to an accurate diagnosis. Dr Saksena draws on his years of experience in teaching and training to show you the physical signs of cardiovascular disease that can be spotted by visual examination. For each sign, a color photograph is paired with explanatory text that: describes the significant features of the sign explains its use in diagnosis identifies the likeliest causes The book provides corroboration of physical signs and other diagnostic information whenever possible and offers extensive references for further study. After an opening chapter on general observations, the author describes signs that can be found in the face, ear, mouth and nose, neck, hand, upper extremity, thorax and back, abdomen, and lower extremity. An appendix covers rarer syndromes associated with cardiovascular disease. Whether you are just developing your diagnostic skills or want to be better able to identify signs of cardiovascular disease, you can count on this atlas for dependable advice.
Innovations in Professional Education for Speech and Language Therapy
The methods by which a student becomes a speech and language therapist have developed since the 1970s and have been influenced by different models of higher and professional education. Although it is comparatively easy to change an aspect of course content, for example to increase the number of learning hours on autism, the means by which the student learns to become a competent professional in practice are more complex. This text discusses some of the exciting ways we are examining issues in professional education. It covers actual content (for example the introduction of dysphagia to the curriculum), new methods for learning (problem-based learning and information technology developments), how speech and language therapists develop competence and what is critical in the transition to becoming a qualified therapist. The longstanding placement problem is addressed by innovative work using different professional learning models, such as peer placements and school-based placements. The reader is provided with detailed practical advice about how to approach these models. The book represents some of the current work in universities and speech and language services in the UK and reveals the creativity and commitment to an expanding subject area.
The Strategic Application of Information Technology in Health Care Organizations
This thoroughly revised and updated second edition of The Strategic Application of Information Technology in Health Care Organizations offers health care executives and managers a balanced analysis of health care information systems. Written by John Glaser-a renowned expert in the field of health care information technology-this important resource shows health care professionals how to use IT to reduce costs, respond to the demands of managed care, develop a continuum of care, and manage and improve the quality of service to patients, payers, and physicians.
Virtual Work Approach to Mechanical Modeling
This book is centred about the Principle of virtual work and the related method for mechanical modelling. It aims at showing and enhancing the polyvalence and versatility of the virtual work approach in the mechanical modelling process. The virtual work statement is set as the principle at the root of a force modelling method that can be implemented on any geometrical description. After experimentally induced hypotheses have been made on the geometrical parameters that describe the concerned system and subsystems, the method provides a unifying framework for building up consistently associated force models where external and internal forces are introduced through their virtual rates of work. Systems described as three-dimensional, curvilinear or planar continua are considered: force models are established with the corresponding equations of motion; the validation process points out that enlarging the domain of relevance of the model for practical applications calls for an enrichment of the geometrical description that takes into account the underlying microstructure.
A Probability and Statistics Companion
An accessible and engaging introduction to the study of probability and statistics Utilizing entertaining real-world examples, A Probability and Statistics Companion provides aunique, interesting, and accessible introduction to probability and statistics. This one-of-a-kind book delves into practical topics that are crucial in the analysis of sample surveys and experimentation. This handy book contains introductory explanations of the major topics in probability and statistics, including hypothesis testing and regression, while also delving into more advanced topics such as the analysis of sample surveys, analysis of experimental data, and statistical process control. The book recognizes that there are many sampling techniques that can actually improve on simple random sampling, and in addition, an introduction to the design of experiments is provided to reflect recent advances in conducting scientific experiments. This blend of coverage results in the development of a deeper understanding and solid foundation for the study of probability and statistics. Additional topical coverage includes: Probability and sample spaces Choosing the best candidate Acceptance sampling Conditional probability Random variables and discrete probability distributions Waiting time problems Continuous probability distributions Statistical inference Nonparametric methods Least squares and medians Recursions and probability Each chapter contains exercises and explorations for readers who wish to conduct independent projects or investigations. The discussion of most methods is complemented with applications to engaging, real-world scenarios such as winning speeds at the Indianapolis 500 and predicting winners of the World Series. In addition, the book enhances the visual nature of the subject with numerous multidimensional graphical representations of the presented examples. A Probability and Statistics Companion is an excellent book for introductory probability and statistics courses at the undergraduate level. It is also a valuable reference for professionals who use statistical concepts to make informed decisions in their day-to-day work.
MATHEMATIK für Physiker und Mathematiker
Rainer Wüst (Jahrgang 1943) studierte von 1962 bis 1968 Mathematik an der Universität München. Danach war er bis 1975 Assistent bei Günter Hellwig an der RWTH Aachen, wo er 1970 promovierte. Nach seiner Habilitation 1975 folgte er einem Ruf auf eine Professur für Mathematik an der TU Berlin, die er bis heute inne hat. Längere Forschungssemester verbrachte er an der Princeton University, NJ (USA), und der Università di Modena (Italien). Seine Arbeitsschwerpunkte sind Mathematische Physik und Funktionalanalysis.
Two and Three Dimensional Calculus
Covers multivariable calculus, starting from the basics and leading up to the three theorems of Green, Gauss, and Stokes, but always with an eye on practical applications. Written for a wide spectrum of undergraduate students by an experienced author, this book provides a very practical approach to advanced calculus—starting from the basics and leading up to the theorems of Green, Gauss, and Stokes. It explains, clearly and concisely, partial differentiation, multiple integration, vectors and vector calculus, and provides end-of-chapter exercises along with their solutions to aid the readers’ understanding. Written in an approachable style and filled with numerous illustrative examples throughout, Two and Three Dimensional Calculus: with Applications in Science and Engineering assumes no prior knowledge of partial differentiation or vectors and explains difficult concepts with easy to follow examples. Rather than concentrating on mathematical structures, the book describes the development of techniques through their use in science and engineering so that students acquire skills that enable them to be used in a wide variety of practical situations. It also has enough rigor to enable those who wish to investigate the more mathematical generalizations found in most mathematics degrees to do so. Assumes no prior knowledge of partial differentiation, multiple integration or vectors Includes easy-to-follow examples throughout to help explain difficult concepts Features end-of-chapter exercises with solutions to exercises in the book. Two and Three Dimensional Calculus: with Applications in Science and Engineering is an ideal textbook for undergraduate students of engineering and applied sciences as well as those needing to use these methods for real problems in industry and commerce.
Differential and Integral Calculus, Volume 1
The classic introduction to the fundamentals of calculus Richard Courant's classic text Differential and Integral Calculus is an essential text for those preparing for a career in physics or applied math. Volume 1 introduces the foundational concepts of «function» and «limit», and offers detailed explanations that illustrate the «why» as well as the «how». Comprehensive coverage of the basics of integrals and differentials includes their applications as well as clearly-defined techniques and essential theorems. Multiple appendices provide supplementary explanation and author notes, as well as solutions and hints for all in-text problems.