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    Data Mining Techniques in Grid Computing Environments

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    Based around eleven international real life case studies and including contributions from leading experts in the field this groundbreaking book explores the need for the grid-enabling of data mining applications and provides a comprehensive study of the technology, techniques and management skills necessary to create them. This book provides a simultaneous design blueprint, user guide, and research agenda for current and future developments and will appeal to a broad audience; from developers and users of data mining and grid technology, to advanced undergraduate and postgraduate students interested in this field.

    Research Handbook for Health Care Professionals

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    The Research Handbook for Health Care Professionals is the essential guide to the entire research process for students and practitioners alike. From conceiving an idea for a project to writing up the findings for publication, the book offers an overview of each stage plus hints and tips, recommendations for further reading and examples spanning a wide range of health professions. The book comprises three sections: Getting Started, Doing Your Research and Writing Up and Dissemination, and includes chapters on key topics such as formulating your research question, writing the initial research protocol, application for ethical approval, research governance, collecting your data, research methods and preparing a poster for a conference.

    Clinical Diabetes Research: Methods and Techniques

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    A practical «how to» guide for multiple methods in metabolism, with a critical and objective discussion of strengths, limitations, and appropriate applications of the described methods. Edited by the winner of the Oskar-Minkowski Prize of the EASD in 2006 Clinical trials in populations at risk of or with overt diabetes mellitus are being performed all around the world to test novel drugs and approaches to managing these diseases. During the last decade, new methods and techniques have been introduced – and are being developed further – that facilitate monitoring of metabolism and even diagnosis of certain defects in human metabolism. While some of these methods are restricted to research facilities, others are already used in clinical practice. The correct beneficial use of these methods requires knowledge of the nature of the techniques and their clinical relevance. Clinical Diabetes Research: Methods and Techniques provides summaries of established state-of-the art-techniques and introduces the new technologies, evaluating their potential in clinical diabetes research. One section compares the efficacy of all metabolic tests that measure insulin action. Another section describes methods that allow quantification of whole body and intracellular metabolic fluxes relevant to diabetes research. The final section focuses on the planning and pitfalls of clinical studies in the field of metabolism. Each chapter throughout the book combines the theoretical basis of the approach with practical recommendations. There are further chapters on the design of clinical trials and ethical considerations. The publication is timely in view of the impressive development of the methods and techniques with their application to understanding the pathophysiology of diabetes, insulin resistance syndromes, obesity, and the metabolic effects of treatment. Clinical Diabetes Research: Methods and Techniques is of great relevance for researchers (from students and post-docs to principal investigators) in the field of human metabolism, clinical endocrinologists and diabetologists who are involved in clinical studies.

    Handbook of Retinal Screening in Diabetes

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    This book, a successor to the highly popular Practical Guide to Polaroid Retinal Photography, describes the essential components of a retinopathy screening programme, including the criteria for referral to an ophthalmologist, drawing upon the experience of the Newcastle system over the last two decades and the National Screening Committee Report upon Eye screening. It is fully illustrated, featuring a new set of 50 digital colour photographs, showing the normal retina and problems associated with diabetes, with explanatory text. «[T]he first concise textbook on retinal screening… well structured and written… provide[s] excellent background reading to those entering the new profession of retinal screening.» PRACTICAL DIABETES INTERNATIONAL

    Paediatric and Neonatal Safe Transfer and Retrieval

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    With over ten thousand inter-hospital transfers of children and neonates now taking place every year in the UK, this book, and the associated training course run by the Advanced Life Support Group (ALSG) have been developed to provide an introduction to the knowledge required to undertake these transfers. Paediatric and Neonatal Safe Transfer and Retrieval (PaNSTaR) is aimed at healthcare professionals either beginning their training in paediatric or neonatal transport and those who are involved in undertaking such transfers on an occasional basis. Developed by a multi-professional group from across the UK, this new title incorporates a systematic approach throughout. This approach is adapted from the adult STaR course and covers the following: an overview of the current delivery of children’s transport services the ACCEPT approach – Assessment – Control – Communication – Evaluation – Preparation and Packaging – Transportation practical issues that are encountered during the transfer process from both an equipment and a clinical perspective special considerations and circumstances that require additional planning useful appendices that contain supporting information, sample checklists and example documentation. For more details on the ALSG training courses please visit the ALSG website at www.alsg.org

    Combating the Threat of Pandemic Influenza

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    Drug discovery for influenza antivirals Priorities for combating pandemic influenza include rapid detection and identification, the quick administration of available drugs to treat the infection, the development of new antivirals, and the development of vaccines. Since lead-time may be required to produce an effective vaccine, antivirals would serve as a key first line of defense in containing an outbreak. Diverse antivirals, acting through different mechanisms, would help stay the development of resistant viruses. Thus, drug discovery for influenza antivirals is an important public health-related endeavor. With chapters contributed by leading international specialists, this guide gets readers up to speed on the latest advances and technologies in diverse approaches to drug discovery, covering: * Existing antivirals, including broadly effective anti-respiratory virus agents * The development of high-throughput screening assays * IFN resistance * The development of nucleic acid-based antiviral drugs * Antiviral RNAi strategies targeting influenza virus * Other promising antiviral drug discovery strategies Combating the Threat of Pandemic Influenza: Drug Discovery Approaches consolidates the latest information on diverse approaches into one comprehensive resource. It is an invaluable, hands-on reference for researchers in medicinal chemistry, pharmaceutical chemistry, drug discovery, biochemistry, virology, microbiology, and public health.

    Implant and Regenerative Therapy in Dentistry

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    Implant and Regenerative Therapy in Dentistry provides a uniquely clear, precise guide to decision making in a variety of clinical situations, from the treatment planning phases to the actual execution of the procedure. It offers concrete and useful decision criteria for various treatment options, as well as equipping readers with key problem-solving and critical apparatus. Implant and Regenerative Therapy In Dentistry anchors itself in the realities of clinical practice. Replete with decision-making algorithms, it acts as both as a reference and a daily companion to its readers, conveying information succinctly, thoroughly and accessibly. Its team of authors, gathered together under the leadership of an exceptional editor, create a book unique in its elegant simplicity and its day-to-day usefulness.

    Pathology of the Hard Dental Tissues

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    This is a seminal text uniquely dedicated to oral hard tissue pathology, presenting the growth of clinical knowledge and advancement in the field in recent years. Starting with a discussion of numerical and formative anomalies and unusual eruption, the book goes on to consider caries, erosion, resorption and toothwear, as well as tooth fractures and discolouration, and ends with a chapter on congenital syndromes with dental anomalies. Pathology of the Hard Dental Tissues is an invaluable reference for specialist practitioners and researchers as well as dental students, combining a scholarly overview of the field with clinical management protocols. Includes prevention techniques as well as treatment regimes Contains many colour clinical photographs Accompanied by a large number of references Provides helpful tables to categorise the causes and characteristics of lesions Written by a leading expert in the field

    Bone Grafting Techniques for Maxillary Implants

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    This book explores the potential of bone grafting techniques to rehabilitate the maxilla through the placement of dental implants. As implant dentistry becomes increasingly well established and sophisticated, this book will help experienced surgeons to involve implant solutions as part of more challenging reconstructions in the upper jaw. Starting with a recap on principles of bone biology, the book then considers implant integration in normal bone and with bone grafts. Grafting procedures are presented depicting a variety of bone harvest sites, followed by onlay and inlay grafting techniques. Approaches to sinus lifting, segmental osteotomy and distraction osteogenesis for augmentation protocols are provided.

    Questions and Answers for Dental Nurses

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    This second edition of Questions and Answers for Dental Nurses reflects the major changes that have taken place in dental nursing over recent years. A valuable self-assessment guide for dental nurses, this edition covers the topics featured on the NEBDN examination, together with the National Vocational Qualification (S/NVQ) in Oral Healthcare, up to Level 3. With mandatory registration in mind, coverage on subjects relevant to Access to Registration Training (ART) is extended. More than just questions and answers, the book often provides guidance on the orientation of examinations, the questions involved and helpful explanatory information on responses. An invaluable resource for trainee dental nurses seeking qualification, as well as returning or refocusing certified dental nurses.