Two factors dominate current molecular biology: the amount of raw data is increasing very rapidly and successful applications in biomedical research require carefully curated and annotated databases. The quality of the experimental data – especially nucleic acid sequences – is satisfactory; however, annotations depend on features inferred from the data rather than measured directly, for instance the identification of genes in genome sequences. It is essential that these inferences are as accurate as possible and this requires human intervention. With the recognition of the importance of accurate database annotation and the requirement for individuals with particular constellations of skills to carry it out, annotators are emerging as specialists within the profession of bioinformatics. This book compiles information about annotation – its current status, what is required to improve it, what skills must be brought to bear on database curation and hence what is the proper training for annotators. The book should be essential reading for all people working on biological databases, both biologists and computer scientists. It will also be of interest to all users of such databases, including molecular biologists, geneticists, protein chemists, clinicians and drug developers.
Essential guide to the new field of transfusion-free medicine and surgery – written by leading experts in the field. Transfusion Free Medicine and Surgery provides a comprehensive approach to a new paradigm shift in the field of blood management. The principles are easy and this platform provides an all-inclusive review of red blood cell production, oxygen delivery, coagulation and the role of blood transfusion in an intensive care setting. Controversial as it may sound, this book opens the door for ethical/legal debates, by putting them into perspective and providing answers to perplexing situations. The economics of blood transfusion and the hidden costs that allude the clinician are also brought into the equation. Why Buy This Book? Provides the groundwork for developing a successful transfusion-free clinical program Includes all key issues related to blood products, blood transfusion and transfusion-free medicine and surgery Discusses controversial issues associated with this new and fast moving field Includes self-assessment questions to help the reader with their continuing professional education and development Transfusion Free Medicine and Surgery is ideal for: Specialists working in transfusion and transfusion-free medicine Haematologists in practice and in training Anyone involved in any surgical discipline, internal medicine, ICU care or anaesthesia who is interested in this field
This popular pocket book has been updated and expanded throughout, providing a concise view of diagnostic haematology, in a convenient and practical format. A Beginner's Guide to Blood Cells is an ideal for; Trainee laboratory technicians and scientists Students studying the physiology or pathology of the blood Those preparing for haematology examinations Why Buy This Book? Unique pocket guide, written by Barbara Bain – a world-renowned expert in the field of blood morphology Outlines the basics of diagnostic haematology Includes an invaluable self-assessment section NEW EDITION – now includes more information on clinical aspects and further tests
Edited by an orthopaedic surgeon and a haematologist who are leading specialists in the treatment of haemophilia, Inhibitors in Patients with Haemophilia reviews the different haemostatic products and protocols for the control of bleeding and surgery in haemophilic patients with inhibitors. The book draws together in a single volume all of the clinical issues involved in the treatment of inhibitors from numerous specialists worldwide. It will be an invaluable resource for all those treating inhibitors in people with haemophilia.
This book is the British Medical Association’s statement on the ethics related to care of the elderly, written and reviewed by a panel of renowned medical ethicists. As such it is an authoritative and considered reference, written in an accessible, non jargon so as to be useful for anyone charged with looking after the elderly. The book includes useful case examples so that it can be used by a range of health professionals and carers who need to know the law and ethics of looking after older people. The authors focus on practical issues such as helping older people stick to their treatment regimes, the sort of information they should be given to give valid consent, and their rights to confidentiality, as well as discussion about where they want to end their lives when it comes to that point.
“An excellent up-to-date comprehensive and practical text book dealing with all aspects of paediatric hepatobiliary disease. It will be useful to both generalists and specialists as it is clinically focused with a problem-solving approach and should be useful for day-to-day as well as more esoteric clinical problems. I found it useful in my general paediatric practice and my trainees have also found it useful. It is very practical with a diagnostic approach and lots of tables and clinical pathways to follow when confronted with day-to-day clinical problems. I have road-tested it in real life with good effect.” – Judging Panel, 2004 BMA Medical Book Competition Diseases of the Liver and Biliary System in Children, Third Edition provides a practical approach to the diagnosis and management of paediatric liver diseases, highlighting the importance of multidisciplinary team working and holistic management of the child and family. This fully revised edition has also been updated to cover recent advances in paediatric hepatology. It includes new chapters describing the effects of liver disease in pregnancy on mother and child through to adolescence. With increasing numbers of young people surviving into adult life this edition addresses the importance of managing adolescent transition effectively. Trainees, practising paediatric gastroenterologists and hepatologists will welcome the practical approach outlined in this text, while other healthcare professionals involved in the management of liver disease in children will find it an accessible and comprehensive reference.
The latest system based addition to the At a Glance series, The Gastrointestinal System at a Glance is a concise and integrated text on the gastrointestinal system. The book is intended as an authoritative and concise account of the field covering anatomy, physiology, biochemistry, pharmacology, and pathology as well as clinical management. The book is divided in to four sections: Basic Structure and Function, Integrated Function and Disorders and Diseases as well as a short section on Diagnosis and Treatment. The structure of the book takes the student from the basic sciences to clinical practice whilst always maintaining an integrated balance and understanding of both aspects. Fantastic diagrams that include a quick summary of clinical presentations will aid students to learn and revise. The Gastrointestinal System at a Glance is ideal as an introduction to the subject, as a companion book for a course, and as a book for revision prior to examinations.
An extremely practical text, this new edition of Diseases of the Liver and Biliary System in Children covers the essentials of paediatric hepatology. The range of material is wide and has been revised and updated to include the latest advances. Many helpful algorithms and tables are included and the references at the end of each chapter have been carefully selected so as to provide the most up-to-date information available. A concluding section comprising some 100 carefully annotated plates, completes this text. Containing the contributions of 23 internationally acclaimed authorities, active both clinically and in research, the book provides an essential guide to the diagnosis and management of paediatric liver diseases, both common and uncommon for all those involved in the care of the child with liver disease. Diseases of the Liver and Biliary System in Children has become THE REFERENCE of choice for the paediatric gastroenterologist, hepatologist and surgeon.
This book is a joint package of a practical manual on how to undertake meta-analysis in medicine together with an accompanying CD-ROM. This provides individuals with access to meta-analysis software and the instructions and guidance on how to undertake them. The software package contains a computer program 'Metanalysis' which performs statistical analyses for the meta-analysis. It has some unique features currently not available in other meta-analysis software packages: ability to import graphics into Word, PowerPoint etc Galbraith's plots cumulative meta-analysis number needed to treat publication bias assessment The graphics generated by the software are in a format compatible with Microsoft PowerPoint. Click here to view sample graphics. Order your copy online today!
This comprehensive, well referenced text provides an up to date review of what is known scientifically about occupational and environmental causes of sickness, disability, and death. It also includes information on the scientific methods used in acquiring this knowledge, making it a complete reference for both clinicians in occupational medicine, and researchers.