This book examines how the interplay between globalization and the assertion of local identities is reshaping the political landscape of Africa. While defending their values against external forces, people simultaneously – and paradoxically – use the interconnectivity of global networks to maximize their particular interests. Focusing on the relation between national identity and state formation, the authors explore the far-reaching consequences of these contradictory dynamics. <br /><br />Although Africa shares many common trends with other parts of the world, it also displays distinctive features. A region characterized by the increased mobility of people, goods and ideas challenges some conventional assumptions of statecraft and also highlights the advantages of federalism – not merely as a constitutional option, but as a pragmatic device for managing diversity and holding fragile states together. The book further explores emerging types of state formation in the same political space, as exemplified by the combination of elements of a kingdom, an independent state and a national power base in the province of KwaZulu-Natal and the careful crafting of an alternative state within a state by the Solidarity Movement in South Africa. <br /><br />Informed by examples and case studies drawn from different parts of Africa, this book will be of great interest to students and scholars of Africa, politics, sociology, media studies and the social sciences more generally.
Since the first edition of Clinical Pancreatology for Practising Gastroenterologists and Surgeons was first published sixteen years ago, the knowledge and clinical management of pancreatic diseases have developed markedly. Thanks to the development of translational research and the “from bench to bedside” concept, much progress from the lab has been applied to clinical practice. Additionally, several highly relevant clinical trials published over the last decade have resulted in the updating and optimisation of clinical guidelines. A new and validated classification of the severity and complications of acute pancreatitis that is firmly rooted in clinical practice has become the basis for the development of minimally invasive approaches to pancreatic necrosis. The etiopathogenic knowledge of chronic pancreatitis and other pancreatopaties, like that associated with diabetes mellitus, has developed significantly. Increased study of cystic pancreatic tumours, which has been reflected in the publication of several guidelines and consensus reports over the last few years, is especially important. Most research efforts have focused on pancreatic cancer, which have led and will further lead to a significant increase in the therapeutic armamentarium against this devastating disease. Finally, many newly published studies have changed the concept, causes, clinical relevance, diagnosis and treatment of exocrine pancreatic insufficiency. Updates based on these developments and more are included in the new edition of Clinical Pancreatology for Practising Gastroenterologists and Surgeons . This new edition of Clinical Pancreatology for Practising Gastroenterologists and Surgeons is a result of the collaboration between the world's leading experts in each area of clinical pancreatology, with the aim of facilitating gastroenterologists, surgeons, oncologists, internists, nutritionists, diabetologists, paediatricians, radiologists, pathologists and other specialists in their daily clinical practice. This book is an indispensable update providing leading knowledge in clinical pancreatology.
Hematopoietic cell transplantation (HCT) provides curative therapy for a variety of diseases. Over the past several decades, significant advances have been made in the field of HCT, to the point where HCT has become an integral part of treatment modality for a variety of hematologic malignancies and some nonmalignant diseases. HCT remains an important treatment option for a wide variety of hematologic and nonhematologic disorders, despite recent advances in the field of immunologic therapies. Factors driving this growth include expanded disease indications, greater donor options (expanding unrelated donor registries and haploidentical HCT), and accommodation of older and less fit recipients. The development of less toxic pretransplant conditioning regimens, more effective prophylaxis of graft-versus-host disease (GVHD), improved infection control, and other advances in transplant technology have resulted in a rapidly growing number of transplant recipients surviving long-term free of the disease for which they were transplanted. The changes over decades in the transplant recipient population and in the practice of HCT will have almost inevitably altered the composition of the long-term survivor population over time. Apart from an increasingly older transplant recipient cohort, the pattern of transplant indications has shifted from the 1990s when chronic myeloid leukemia made up a significant proportion of allo-HCT indications. Changes in cell source, donor types, conditioning regimens, GVHD prophylaxis, and supportive care have all occurred, with ongoing reductions in both relapse and non-relapse mortality (NRM) have been demonstrated. These patients have increased risks for a variety of late complications, which can cause morbidity and mortality. Most long-term survivors return to the care of their local hematologists/oncologists or primary care physicians, who may not be familiar with specialized monitoring and management of long complications after HCT for this patient population. As HCT survivorship increases, the focus of care has shifted to the identification and treatment of long-term complications that may affect quality of life and long-term morbidity and mortality. Preventive care as well as early detection and treatments are important aspects to reducing morbidity and mortality in long-term survivors after allo-HCT. This second edition, Blood and Marrow Transplantation Long-Term Management: Survivorship after Transplant , provides up-to-date information about diagnosis, screening, treatment, and long-term surveillance of long-term survivors after HCT.
Das Archiv hat Konjunktur. War es früher lediglich ein Magazin, ein Aufbewahrungsort für Dokumente, eine Sammlung literarischer Hinterlassenschaften, so hat sich seine Funktion in den letzten Jahrzehnten radikal gewandelt.
Wurden früher Schätze aus der Vergangenheit konserviert, öffnet sich das Archiv der Gegenwart: Beschränkte man sich auf den Erwerb von Nachlässen, werden heutzutage bereits Konvolute von jüngeren Autor*innen aufgenommen, womit dem Archiv eine Definitionsmacht bei der Kanonbildung zufällt. Nachlassbewusstsein ist bei Schriftsteller*innen ausgeprägter als in früheren Zeiten. Das Archiv bestimmt die literarische Produktion, sofern sich der Text selbst nicht gleich als Archiv versteht.
Das Archiv entwickelt selbst kulturelle Praktiken, wird dank der Digitalisierung von Beständen zum virtuellen Ort der Wissensproduktion, durch die Ausstellung des Originals und seiner Aura andererseits zum Museum. Neben der Erweiterung traditioneller Archivarbeit um transnationale Forschungsfelder, Autorenbibliotheken und Verlagsarchive steht im Mittelpunkt des Bandes die Frage nach den Aufgaben eines Archivs im digitalen 21. Jahrhundert.