Principles of Virology, Volume 2. S. Jane Flint

Introduction Discovering Antiviral Compounds Drug Resistance Examples of Antiviral Drugs Expanding Targets for Antiviral Drug Development Two Stories of Antiviral Success Perspectives References

      14  9 Therapeutic Viruses Introduction Phage Therapy Oncolytic Animal Viruses Gene Therapy Vaccine Vectors Perspectives References

      15  10 Virus Evolution Virus Evolution How Do Virus Populations Evolve? The Origin of Viruses Host-Virus Relationships Drive Evolution Lessons from Paleovirology Perspectives References

      16  11 Emergence The Spectrum of Host-Virus Interactions Encountering New Hosts: Humans Constantly Provide New Venues for Infection Common Sources for Animal-to-Human Transmission Viral Diseases That Illustrate the Drivers of Emergence The Contribution to Emergence of Mutation, Recombination, or Reassortment New Technologies Uncover Previously Unrecognized Viruses Perceptions and Possibilities Perspectives References

      17  12 Human Immunodeficiency Virus Type I Pathogenesis Introduction HIV-1 Is a Lentivirus Entry and Transmission The Course of Infection Virus Reproduction Immune Responses to HIV-1 HIV-1 and Cancer Prospects for Treatment and Prevention Perspectives References

      18  13 Unusual Infectious Agents Introduction Viroids Satellite Viruses and RNAs Prions and Transmissible Spongiform Encephalopathies Perspectives References

      19  APPENDIX: Epidemiology and Pathogenesis of Selected Human Viruses Adenoviruses Arenaviruses Bunyaviruses Caliciviruses Coronaviruses Filoviruses Flaviviruses Flaviviruses Flaviviruses Hepadnaviruses Herpesviruses Herpesviruses Herpesviruses Orthomyxoviruses Papillomaviruses Paramyxoviruses Paramyxoviruses Picornaviruses Picornaviruses Picornaviruses Polyomaviruses Poxviruses Reoviruses Reoviruses Retroviruses Retroviruses Rhabdoviruses