Fundamentals of Analytical Toxicology. Robin Whelpton

parameters 16.10 Disease 16.11 Pharmacokinetics and the interpretation of results 16.12 Summary References

      12  Section D: Analytical Toxicology 17 Toxicology Testing at the Point of Contact 17.1 Introduction 17.2 Use of point of contact testing 17.3 Toxicology testing at the point of contact 17.4 Interferences and adulterants 17.5 Quality assessment 17.6 Summary References 18 Laboratory Testing for Substance Misuse 18.1 Introduction 18.2 Urine testing 18.3 Oral fluid testing 18.4 Blood testing 18.5 Hair testing 18.6 Breath testing 18.7 Sweat testing 18.8 Summary References 19 General Analytical Toxicology 19.1 Introduction 19.2 Gas chromatography 19.3 Gas chromatography-mass spectrometry 19.4 Liquid chromatography 19.5 Liquid chromatography-mass spectrometry 19.6 Liquid chromatography-high resolution mass spectrometry 19.7 Summary References 20 Therapeutic Drug Monitoring 20.1 Introduction 20.2 Sample collection 20.3 Sample types 20.4 Analytical methods 20.5 Factors affecting interpretation of results 20.6 Gazetteer 20.7 Summary References 21 Trace Elements and Toxic Metals 21.1 Introduction 21.2 Sample collection and storage 21.3 Sample preparation 21.4 Atomic spectrometry 21.5 Colorimetry and fluorimetry 21.6 Electrochemical methods 21.7 Catalytic methods 21.8 Neutron activation analysis 21.9 Chromatographic methods 21.10 Quality assessment 21.11 Summary References 22 Clinical Interpretation of Analytical Results 22.1 Introduction 22.2 Clinical toxicology 22.3 Forensic toxicology 22.4 Gazetteer 22.5 Sources of further information 22.6 Summary References

      13  Index

      14  End User License Agreement

      List of Tables

      1 Chapter 1Table 1.1 Methods for the analysis of drugs and other organic poisons in biol...Table 1.2 Methods for the analysis of toxic metals in biological materialsTable 1.3 Steps in undertaking an analytical toxicological investigationTable 1.4 Summary of chiral nomenclatureTable 1.5 Some terms used in stereochemistryTable 1.6 Terms used when reporting method validationTable 1.7 Some analytes not normally included in analytical toxicology screen...

      2 Chapter 2Table 2.1 Types of variables affecting clinical samplesTable 2.2 Some clinical sample typesTable 2.3 Anticoagulants forin vitro useTable 2.4 Sample requirements: general analytical toxicologyTable 2.5 Sample requirements: post-mortem biochemistry and toxicologyTable 2.6 Advantages and disadvantages of different sample types in analytica...Table 2.7 Some possible causes of coloured urineTable 2.8 Smells