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Fundamental Bioengineering

Jens Petter Nielsen

A thorough introduction to the basics of bioengineering, with a focus on applications in the emerging «white» biotechnology industry. As such, this latest volume in the «Advanced Biotechnology» series covers the principles for the design and analysis of industrial bioprocesses as well as the design of bioremediation systems, and several biomedical applications. No fewer than seven chapters introduce stoichiometry, kinetics, thermodynamics and the design of ideal and real bioreactors, illustrated by more than 50 practical examples. Further chapters deal with the tools that enable an understanding of the behavior of cell cultures and enzymatically catalyzed reactions, while others discuss the analysis of cultures at the level of the cell, as well as structural frameworks for the successful scale-up of bioreactions. In addition, a short survey of downstream processing options and the control of bioreactions is given. With contributions from leading experts in industry and academia, this is a comprehensive source of information peer-reviewed by experts in the field.

Applied Bioengineering. Innovations and Future Directions

Jens Petter Nielsen

A comprehensive overview of the topic, highlighting recent developments, ongoing research trends and future directions. Experts from Europe, Asia and the US cover five core areas of imminent importance to the food, feed, pharmaceutical and water treatment industries in terms of sustainable and innovative processing and production. In the field of enzyme engineering, they summarize historic developments and provide an overview of molecular enzyme engineering, while also discussing key principles of microbial process engineering, including chapters on process development and control. Further sections deal with animal and plant cell culture engineering. The final section of the book deals with environmental topics and highlights the application of bioengineering principles in waste treatment and the recovery of valuable resources. With its cutting-edge visions, extensive discussions and unique perspectives, this is a ready reference for biotechnologists, bioengineers, bioengineers, biotechnological institutes, and environmental chemists.

Layer-by-Layer Films for Biomedical Applications

Frank Caruso

The layer-by-layer (LbL) deposition technique is a versatile approach for preparing nanoscale multimaterial films: the fabrication of multicomposite films by the LbL procedure allows the combination of literally hundreds of different materials with nanometer thickness in a single device to obtain novel or superior performance. In the last 15 years the LbL technique has seen considerable developments and has now reached a point where it is beginning to find applications in bioengineering and biomedical engineering. The book gives a thorough overview of applications of the LbL technique in the context of bioengineering and biomedical engineering where the last years have witnessed tremendous progress. The first part familiarizes the reader with the specifics of cell-film interactions that need to be taken into account for successful application of the LbL method in biological environments. The second part focuses on LbL-derived small drug delivery systems and antibacterial agents, and the third part covers nano- and microcapsules as drug carriers and biosensors. The fourth and last part focuses on larger-scale biomedical applications of the LbL method such as engineered tissues and implant coatings.

Technicity vs Scientificity. Complementarities and Rivalries

Georges Guille-Escuret

The relationship between technicity and scientificity is often overlooked or avoided despite being a determining factor for establishing interdisciplinarity. By focusing on this relationship and highlighting a number of its ramifications, this book sheds light on the hidden or skewed stakes that condition a wide array of scientific projects. The authors present different approaches based on their own professional experience, focusing on the technique–science relationship in domains as diverse as brain mapping, the decipherment of Mycenaean writing and the design process. Each chapter presents varying and often opposing epistemological conclusions to provide the reader with a wide breadth of examples in different fields. Although the scope of this book is far from exhaustive, it serves as a starting point for the necessary and long-overdue clarification of the relationship between these neighboring, yet disjointed, sectors.

International Textbook of Diabetes Mellitus

E. Ferrannini

The International Textbook of Diabetes Mellitus has been a successful, well-respected medical textbook for almost 20 years, over 3 editions. Encyclopaedic and international in scope, the textbook covers all aspects of diabetes ensuring a truly multidisciplinary and global approach. Sections covered include epidemiology, diagnosis, pathogenesis, management and complications of diabetes and public health issues worldwide. It incorporates a vast amount of new data regarding the scientific understanding and clinical management of this disease, with each new edition always reflecting the substantial advances in the field. Whereas other diabetes textbooks are primarily clinical with less focus on the basic science behind diabetes, ITDM's primary philosophy has always been to comprehensively cover the basic science of metabolism, linking this closely to the pathophysiology and clinical aspects of the disease. Edited by four world-famous diabetes specialists, the book is divided into 13 sections, each section edited by a section editor of major international prominence. As well as covering all aspects of diabetes, from epidemiology and pathophysiology to the management of the condition and the complications that arise, this fourth edition also includes two new sections on NAFLD, NASH and non-traditional associations with diabetes, and clinical trial evidence in diabetes. This fourth edition of an internationally recognised textbook will once again provide all those involved in diabetes research and development, as well as diabetes specialists with the most comprehensive scientific reference book on diabetes available.

Biofilms in the Dairy Industry

Brooks John Graham

In recent years, the formation and impacts of biofilms on dairy manufacturing have been studied extensively, from the effects of microbial enzymes produced during transportation of raw milk to the mechanisms of biofilm formation by thermophilic spore-forming bacteria. The dairy industry now has a better understanding of biofilms and of approaches that may be adopted to reduce the impacts that biofilms have on manufacturing efficiencies and the quality of dairy products. Biofilms in the Dairy Industry provides a comprehensive overview of biofilm-related issues facing the dairy sector. The book is a cornerstone for a better understanding of the current science and of ways to reduce the occurrence of biofilms associated with dairy manufacturing. The introductory section covers the definition and basic concepts of biofilm formation and development, and provides an overview of problems caused by the occurrence of biofilms along the dairy manufacturing chain. The second section of the book focuses on specific biofilm-related issues, including the quality of raw milk influenced by biofilms, biofilm formation by thermoduric streptococci and thermophilic spore-forming bacteria in dairy manufacturing plants, the presence of pathogens in biofilms, and biofilms associated with dairy waste effluent. The final section of the book looks at the application of modelling approaches to control biofilms. Potential solutions for reducing contamination throughout the dairy manufacturing chain are also presented. Essential to professionals in the global dairy sector, Biofilms in the Dairy Industry will be of great interest to anyone in the food and beverage, academic and government sectors. This text is specifically targeted at dairy professionals who aim to improve the quality and consistency of dairy products and improve the efficiency of dairy product manufacture through optimizing the use of dairy manufacturing plant and reducing operating costs.

Membrane Reactor Engineering. Applications for a Greener Process Industry

Angelo Basile

Uniquely focussed on the engineering aspects of membrane reactors Provides tools for analysis with specific regard to sustainability Applications include water treatment, wastewater recycling, desalination, biorefineries, agro-food production Membrane reactors can bring energy saving, reduced environmental impact and lower operating costs

Marine Ornamental Species Aquaculture

Ricardo Calado

The global trade of aquatic organisms for home and public aquariums, along with associated equipment and accessories, has become a multi-billion dollar industry. Aquaculture of marine ornamental species, still in its infancy, is recognized as a viable alternative to wild collection as it can supplement or replace the supply of wild caught specimens and potentially help recover natural populations through restocking. This book collects into a single work the most up-to-date information currently available on the aquaculture of marine ornamental species. It includes the contributions of more than 50 leading scientists and experts on different topics relevant for the aquaculture of the most emblematic groups of organisms traded for reef aquariums. From clownfish, to angelfish, tangs and seahorses, as well as corals, anemones, shrimps, giant clams and several other reef organisms, all issues related with the husbandry, breeding, and trade are addressed, with explanatory schemes and illustrations being used to help in understanding the most complex topics addressed. Marine Ornamental Species Aquaculture is a key reference for scientists and academics in research institutes and universities, public and private aquaria, as well as for hobbyists. Entrepreneurs will also find this book an important resource, as the culture of marine ornamental species is analyzed from a business oriented perspective, highlighting the risks and opportunities of commercial scale aquaculture of marine ornamentals.

Thermoelectric Bi2Te3 Nanomaterials

Oliver Eibl

Edited by the initiators of a priority research program funded by the German Science Foundation and written by an international team of key players, this is the first book to provide an overview of nanostructured thermoelectric materials – putting the new developments into perspective alongside conventional thermoelectrics. As such, it reviews the current state of research on thermoelectric Bi2Te3 nanomaterials, covering advanced methods of materials synthesis, characterization of materials structures and thermoelectric properties, as well as advances in the theory and modeling of transport properties. Nanomaterials-based thermoelectric devices are also discussed with respect to their properties, their suitability for different energy generation applications, and in light of their commercialization potential. An outlook on the chances, challenges and future directions of research rounds off the book, giving a straightforward account of the fundamental and technical problems – plus ways to overcome them.

Lignin and Lignans as Renewable Raw Materials. Chemistry, Technology and Applications

Joaquin Isac-Garcia

As naturally occurring and abundant sources of non-fossil carbon, lignin and lignans offer exciting possibilities as a source of commercially valuable products, moving away from petrochemical-based feedstocks in favour of renewable raw materials. Lignin can be used directly in fields such as agriculture, livestock, soil rehabilitation, bioremediation and the polymer industry, or it can be chemically modified for the fabrication of specialty and high-value chemicals such as resins, adhesives, fuels and greases. Lignin and Lignans as Renewable Raw Materials presents a multidisciplinary overview of the state-of-the-art and future prospects of lignin and lignans. The book discusses the origin, structure, function and applications of both types of compounds, describing the main resources and values of these products as carbon raw materials. Topics covered include: • Structure and physicochemical properties • Lignin detection methods • Biosynthesis of lignin • Isolation methods • Characterization and modification of lignins • Applications of modified and unmodified lignins • Lignans: structure, chemical and biological properties • Future perspectives This book is a comprehensive resource for researchers, scientists and engineers in academia and industry working on new possibilities for the application of renewable raw materials. For more information on the Wiley Series in Renewable Resources, visit www.wiley.com/go/rrs