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Скачивание или чтение онлайн электронных книг.NMR in Pharmaceutical Science
NMR in Pharmaceutical Sciences is intended to be a comprehensive source of information for the many individuals that utilize MR in studies of relevance to the pharmaceutical sector. The book is intended to educate and inform those who develop and apply MR approaches within the wider pharmaceutical environment, emphasizing the toolbox that is available to spectroscopists and radiologists. This book is structured on the key processes in drug discovery, development and manufacture, but underpinned by an understanding of fundamental NMR principles and the unique contribution that NMR (including MRI) can provide. After an introductory chapter, which constitutes an overview, the content is organised into five sections. The first section is on the basics of NMR theory and relevant experimental methods. The rest follow a sequence based on the chronology of drug discovery and development, firstly 'Idea to Lead' then 'Lead to Drug Candidate', followed by 'Clinical Development', and finally 'Drug Manufacture'. The thirty one chapters cover a vast range of topics from analytical chemistry, including aspects involved in regulatory matters and in the prevention of fraud, to clinical imaging studies. Whilst this comprehensive volume will be essential reading for many scientists based in pharmaceutical and related industries, it should also be of considerable value to a much wider range of academic scientists whose research is related to the various aspects of pharmaceutical R&D; for them it will supply vital understanding of pharmaceutical industrial concerns and the basis of key decision making processes. About eMagRes Handbooks eMagRes (formerly the Encyclopedia of Magnetic Resonance) publishes a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fields, is enabling the publication of a series of eMagRes Handbooks on specific areas of NMR and MRI. The chapters of each of these handbooks will comprise a carefully chosen selection of eMagRes articles. In consultation with the eMagRes Editorial Board, the eMagRes handbooks are coherently planned in advance by specially-selected Editors, and new articles are written to give appropriate complete coverage. The handbooks are intended to be of value and interest to research students, postdoctoral fellows and other researchers learning about the scientific area in question and undertaking relevant experiments, whether in academia or industry. Have the content of this handbook and the complete content of eMagRes at your fingertips! Visit: www.wileyonlinelibrary.com/ref/eMagRes
Advances in Bioenergy. The Sustainability Challenge
The increasing deployment of bioenergy frequently raises issues regarding the use of land and raw materials, infrastructure and logistics. In light of these sometimes conflicting interests Advances in Bioenergy provides an objective and wide-ranging overview of the technology, economics and policy of bioenergy. Offering an authoritative multidisciplinary summary of the opportunities and challenges associated with bioenergy utilization, with international researchers give up-to-date and detailed information on key issues for biomass production and conversion to energy. Key features: *Discusses different bioenergy uses such as transportation fuels, electricity and heat production. *Assesses emerging fields such as bio-based chemicals and bio-refineries. *Debates conditions for the mobilization of sustainable bioenergy supply chains and outlines governance systems to support this mobilization. * Dedicated chapters to sustainability governance and emerging tools such as certification systems and standards supporting growth of a sustainable bioenergy industry. *Considers the political, environmental, social and cultural context related to the demand for energy resources, the impact of this demand on the world around us, and the choices and behaviours of consumers. This book will be a vital reference to engineers, researchers and students that need an accessible overview of the bioenergy area. It will also be of high value for politicians, policymakers and industry leaders that need to stay up to date with the state-of-the-art science and technology in this area.
Chemically Reacting Flow. Theory, Modeling, and Simulation
A guide to the theoretical underpinnings and practical applications of chemically reacting flow Chemically Reacting Flow: Theory, Modeling, and Simulation, Second Edition combines fundamental concepts in fluid mechanics and physical chemistry while helping students and professionals to develop the analytical and simulation skills needed to solve real-world engineering problems. The authors clearly explain the theoretical and computational building blocks enabling readers to extend the approaches described to related or entirely new applications. New to this Second Edition are substantially revised and reorganized coverage of topics treated in the first edition. New material in the book includes two important areas of active research: reactive porous-media flows and electrochemical kinetics. These topics create bridges between traditional fluid-flow simulation approaches and transport within porous-media electrochemical systems. The first half of the book is devoted to multicomponent fluid-mechanical fundamentals. In the second half the authors provide the necessary fundamental background needed to couple reaction chemistry into complex reacting-flow models. Coverage of such topics is presented in self-contained chapters, allowing a great deal of flexibility in course curriculum design. • Features new chapters on reactive porous-media flow, electrochemistry, chemical thermodynamics, transport properties, and solving differential equations in MATLAB • Provides the theoretical underpinnings and practical applications of chemically reacting flow • Emphasizes fundamentals, allowing the analyst to understand fundamental theory underlying reacting-flow simulations • Helps readers to acquire greater facility in the derivation and solution of conservation equations in new or unusual circumstances • Reorganized to facilitate use as a class text and now including a solutions manual for academic adopters Computer simulation of reactive systems is highly efficient and cost-effective in the development, enhancement, and optimization of chemical processes. Chemically Reacting Flow: Theory, Modeling, and Simulation, Second Edition helps prepare graduate students in mechanical or chemical engineering, as well as research professionals in those fields take utmost advantage of that powerful capability.
Optimal Design of Switching Power Supply
A contemporary evaluation of switching power design methods with real world applications • Written by a leading author renowned in his field • Focuses on switching power supply design, manufacture and debugging • Switching power supplies have relevance for contemporary applications including mobile phone chargers, laptops and PCs • Based on the authors' successful «Switching Power Optimized Design 2nd Edition» (in Chinese) • Highly illustrated with design examples of real world applications
A Companion to Contemporary French Cinema
A Companion to Contemporary French Cinema presents a comprehensive collection of original essays addressing all aspects of French cinema from 1990 to the present day. Features original contributions from top film scholars relating to all aspects of contemporary French cinema Includes new research on matters relating to the political economy of contemporary French cinema, developments in cinema policy, audience attendance, and the types, building, and renovation of theaters Utilizes groundbreaking research on cinema beyond the fiction film and the cinema-theater such as documentary, amateur, and digital filmmaking Contains an unusually large range of methodological approaches and perspectives, including those of genre, gender, auteur, industry, economic, star, postcolonial and psychoanalytic studies Includes essays by important French cinema scholars from France, the U.S., and New Zealand, many of whose work is here presented in English for the first time
Enablers for Smart Cities
Smart cities are a new vision for urban development. They integrate information and communication technology infrastructures – in the domains of artificial intelligence, distributed and cloud computing, and sensor networks – into a city, to facilitate quality of life for its citizens and sustainable growth. This book explores various concepts for the development of these new technologies (including agent-oriented programming, broadband infrastructures, wireless sensor networks, Internet-based networked applications, open data and open platforms), and how they can provide smart services and enablers in a range of public domains. The most significant research, both established and emerging, is brought together to enable academics and practitioners to investigate the possibilities of smart cities, and to generate the knowledge and solutions required to develop and maintain them.
Advanced Magnetic and Optical Materials
Advanced Magnetic and OpticalMaterials offers detailed up-to-date chapters on the functional optical and magnetic materials, engineering of quantum structures, high-tech magnets, characterization and new applications. It brings together innovative methodologies and strategies adopted in the research and development of the subject and all the contributors are established specialists in the research area. The 14 chapters are organized in two parts: Part 1: Magnetic Materials Magnetic Heterostructures and superconducting order Magnetic Antiresonance in nanocomposites Magnetic bioactive glass-ceramics for bone healing and hyperthermic treatment of solid tumors Magnetic iron oxide nanoparticles Magnetic nanomaterial-based anticancer therapy Theoretical study of strained carbon-based nanobelts: Structural, energetical, electronic, and magnetic properties Room temperature molecular magnets – Modeling and applications Part 2: Optical Materials Advances and future of white LED phosphors for solid-state lighting Design of luminescent materials with “Turn-on/off” response for anions and cations Recent advancements in luminescent materials and their potential applications Strongly confined quantum dots: Emission limiting, photonic doping, and magneto-optical effects Microstructure characterization of some quantum dots synthesized by mechanical alloying Advances in functional luminescent materials and phosphors Development in organic light emitting materials and their potential applications
Neuromodulation in Psychiatry
Edited by an expert multidisciplinary team, Neuromodulation in Psychiatry is the first reference guide to address both invasive and non-invasive neuromodulation strategies used in psychiatry. Covers basic principles, technical aspects, clinical applications and ethical considerations Presents up-to-date evidence in comprehensive summaries suitable for all levels of experience Each technique is clearly explained along with its implications for real-world clinical practice Allows psychiatrists to make informed decisions regarding neuromodulation for their patients
Applied RVE Reconstruction and Homogenization of Heterogeneous Materials
Statistical correlation functions are a well-known class of statistical descriptors that can be used to describe the morphology and the microstructure-properties relationship. A comprehensive study has been performed for the use of these correlation functions for the reconstruction and homogenization in nano-composite materials. Correlation functions are measured from different techniques such as microscopy (SEM or TEM), small angle X-ray scattering (SAXS) and can be generated through Monte Carlo simulations. In this book, different experimental techniques such as SAXS and image processing are presented, which are used to measure two-point correlation function correlation for multi-phase polymer composites. Higher order correlation functions must be calculated or measured to increase the precision of the statistical continuum approach. To achieve this aim, a new approximation methodology is utilized to obtain N-point correlation functions for multiphase heterogeneous materials. The two-point functions measured by different techniques have been exploited to reconstruct the microstructure of heterogeneous media. Statistical continuum theory is used to predict the effective thermal conductivity and elastic modulus of polymer composites. N-point probability functions as statistical descriptors of inclusions have been exploited to solve strong contrast homogenization for effective thermal conductivity and elastic modulus properties of heterogeneous materials. Finally, reconstructed microstructure is used to calculate effective properties and damage modeling of heterogeneous materials.
LED Lighting. Technology and Perception
Promoting the design, application and evaluation of visually and electrically effective LED light sources and luminaires for general indoor lighting as well as outdoor and vehicle lighting, this book combines the knowledge of LED lighting technology with human perceptual aspects for lighting scientists and engineers. After an introduction to the human visual system and current radiometry, photometry and color science, the basics of LED chip and phosphor technology are described followed by specific issues of LED radiometry and the optical, thermal and electric modeling of LEDs. This is supplemented by the relevant practical issues of pulsed LEDs, remote phosphor LEDs and the aging of LED light sources. Relevant human visual aspects closely related to LED technology are described in detail for the photopic and the mesopic range of vision, including color rendering, binning, whiteness, Circadian issues, as well as flicker perception, brightness, visual performance, conspicuity and disability glare. The topic of LED luminaires is discussed in a separate chapter, including retrofit LED lamps, LED-based road and street luminaires and LED luminaires for museum and school lighting. Specific sections are devoted to the modularity of LED luminaires, their aging and the planning and evaluation methods of new LED installations. The whole is rounded off by a summary and a look towards future developments.