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Written by a highly regarded author with industrial and academic experience, this new edition of an established bestselling book provides practical guidance for students, researchers, and those in chemical engineering. The book includes a new section on sustainable energy, with sections on carbon capture and sequestration, as a result of increasing environmental awareness; and a companion website that includes problems, worked solutions, and Excel spreadsheets to enable students to carry out complex calculations.
Ligand Design in Medicinal Inorganic Chemistry
Increasing the potency of therapeutic compounds, while limiting side-effects, is a common goal in medicinal chemistry. Ligands that effectively bind metal ions and also include specific features to enhance targeting, reporting, and overall efficacy are driving innovation in areas of disease diagnosis and therapy. Ligand Design in Medicinal Inorganic Chemistry presents the state-of-the-art in ligand design for medicinal inorganic chemistry applications. Each individual chapter describes and explores the application of compounds that either target a disease site, or are activated by a disease-specific biological process. Ligand design is discussed in the following areas: Platinum, Ruthenium, and Gold-containing anticancer agents Emissive metal-based optical probes Metal-based antimalarial agents Metal overload disorders Modulation of metal-protein interactions in neurodegenerative diseases Photoactivatable metal complexes and their use in biology and medicine Radiodiagnostic agents and Magnetic Resonance Imaging (MRI) agents Carbohydrate-containing ligands and Schiff-base ligands in Medicinal Inorganic Chemistry Metalloprotein inhibitors Ligand Design in Medicinal Inorganic Chemistry provides graduate students, industrial chemists and academic researchers with a launching pad for new research in medicinal chemistry.
microRNAs in Toxicology and Medicine
During the past decade it has become evident that microRNAs regulate gene expressions and control many developmental and cellular processes in eukaryotic organisms. Recent studies suggest that microRNAs play an important role in toxicogenomics and are likely to play an important role in a range of human diseases including cancer. microRNAs in Toxicology and Medicine is a comprehensive and authoritative compilation of up-to-date developments in this emerging research area, presented by internationally recognized investigators. It focuses on the role of microRNA in biology and medicine with a special emphasis on toxicology. Divided into six parts, topics covered include: microRNA and toxicology – including environmental toxicants and perturbation of miRNA signaling; microRNA, and Disease States featuring microRNAs in drug-induced liver toxicity, microRNAs and Inflammation the regulatory role of microRNA in mutagenesis, microRNAs and cancer, and the role of microRNAs in tumor progression and therapy, as well as current understanding of microRNAs as therapeutic targets in cancer microRNAs and disease states microRNAs and stem cells microRNAs and genomics microRNAs and epigenomics microRNAs and biomarkers – including body fluid microRNAs as toxicological biomarkers, cell-free microRNAs as biomarkers in human diseases, and circulating microRNAs as biomarkers of drug-induced pancreatitis microRNAs in Toxicology and Medicine is an essential insight into the current trends and future directions of research in this rapidly expanding field for investigators, toxicologists, risk assessors, and regulators in academia, medical settings, industry, and government.
An Introduction to Modern Cosmology
An Introduction to Modern Cosmology Third Edition is an accessible account of modern cosmological ideas. The Big Bang Cosmology is explored, looking at its observational successes in explaining the expansion of the Universe, the existence and properties of the cosmic microwave background, and the origin of light elements in the universe. Properties of the very early Universe are also covered, including the motivation for a rapid period of expansion known as cosmological inflation. The third edition brings this established undergraduate textbook up-to-date with the rapidly evolving observational situation. This fully revised edition of a bestseller takes an approach which is grounded in physics with a logical flow of chapters leading the reader from basic ideas of the expansion described by the Friedman equations to some of the more advanced ideas about the early universe. It also incorporates up-to-date results from the Planck mission, which imaged the anisotropies of the Cosmic Microwave Background radiation over the whole sky. The Advanced Topic sections present subjects with more detailed mathematical approaches to give greater depth to discussions. Student problems with hints for solving them and numerical answers are embedded in the chapters to facilitate the reader’s understanding and learning. Cosmology is now part of the core in many degree programs. This current, clear and concise introductory text is relevant to a wide range of astronomy programs worldwide and is essential reading for undergraduates and Masters students, as well as anyone starting research in cosmology. Supplementary material, including full-colour images, updates and links for students and instructors, is available on the author’s website: http://www.roe.ac.uk/~arl/.
Basic Guide to Medical Emergencies in the Dental Practice
The Basic Guide to Medical Emergencies in the Dental Practice is a must-have book for all dental care professionals and general dentists. Written in a clear and accessible style, this second edition has been fully revised and updated in line with the latest guidelines. Chapters cover such key topics as the ABCDE approach to patient assessment, resuscitation equipment, respiratory and cardiac disorders, paediatric emergencies, and legal and ethical issues. Readers will also find two brand new chapters on the principles of first aid, and drugs for medical emergencies. Follows Resuscitation Council (UK) Guidelines Companion website with self-assessment exercises, serving as revision as well as non-verifiable CPD credit Over 50% new images Student friendly colourful layout with learning outcomes
Luminescence of Lanthanide Ions in Coordination Compounds and Nanomaterials
This comprehensive book presents the theoretical principles, current applications and latest research developments in the field of luminescent lanthanide complexes; a rapidly developing area of research which is attracting increasing interest amongst the scientific community. Luminescence of Lanthanide Ions in Coordination Compounds and Nanomaterials begins with an introduction to the basic theoretical and practical aspects of lanthanide ion luminescence, and the spectroscopic techniques used to evaluate the efficiency of luminescence. Subsequent chapters introduce a variety of different applications including: • Circularly polarized luminescence • Luminescence bioimaging with lanthanide complexes • Two-photon absorption of lanthanide complexes • Chemosensors • Upconversion luminescence • Excitation spectroscopy • Heterometallic complexes containing lanthanides Each chapter presents a detailed introduction to the application, followed by a description of experimental techniques specific to the area and an extensive review of recent literature. This book is a valuable introduction to the literature for scientists new to the field, as well as providing the more experienced researcher with a comprehensive resource covering the most relevant information in the field; a ‘one stop shop’ for all key references.
Molecular and Quantitative Animal Genetics
Animal genetics is a foundational discipline in the fields of animal science, animal breeding, and veterinary sciences. While genetics underpins the healthy development and breeding of all living organisms, this is especially true in domestic animals, specifically with respect to breeding for key traits. Molecular and Quantitative Animal Genetics is a new textbook that takes an innovative approach, looking at both quantitative and molecular breeding approaches. The bookprovides a comprehensive introduction to genetic principles and their applications in animal breeding. This text provides a useful overview for those new to the field of animal genetics and breeding, covering a diverse array of topics ranging from population and quantitative genetics to epigenetics and biotechnology. Molecular and Quantitative Animal Genetics will be an important and invaluable educational resource for undergraduate and graduate students and animal agriculture professionals. Divided into six sections pairing fundamental principles with useful applications, the book's comprehensive coverage will make it an ideal fit for students studying animal breeding and genetics at any level.
The Architect's Handbook of Professional Practice
American Instituteof Architects
The definitive guide to architectural practice Business, legal, and technical trends in architecture are constantly changing. The Architect's Handbook of Professional Practice has offered firms the latest guidance on those trends since 1920. The Fifteenth Edition of this indispensable guide features nearly two-thirds new content and covers all aspects of contemporary practice, including updated material on: Small-firm practice, use of technologies such as BIM, and project delivery methods, such as IPD and architect-led design-build Career development and licensure for emerging professionals and state-mandated continuing education for established architects Business management topics, such as organizational development, marketing, finance, and human resources Research as an integrated aspect of architectural practice, featuring such topics as evidence-based design and research in a small-firm context The Fifteenth Edition of The Architect's Handbook of Professional Practice includes access to a website that contains samples of all AIA Contract Documents (in PDF format for Mac and PC computers). With comprehensive coverage of contemporary practices in architecture, as well as the latest developments and trends in the industry, The Architect's Handbook of Professional Practice continues to be the essential reference for every architect who must meet the challenges of today's marketplace with insight and confidence.
Communications and Information Infrastructure Security
Communication and Information Systems Security features articles from the Wiley Handbook of Science and Technology for Homeland Security covering strategies for protecting the telecommunications sector, wireless security, advanced web based technology for emergency situations. Science and technology for critical infrastructure consequence mitigation are also discussed.
Magnetic Resonance Imaging for Groundwater
This book presents the basics of the non-invasive geophysical method for groundwater investigation, called Magnetic Resonance Sounding (MRS) or Surface Nuclear Magnetic Resonance (SNMR), and its practical application to the problems of groundwater localization and aquifer characterization. The method is based on the nuclear magnetic resonance (NMR) phenomenon and is selectively sensitive to groundwater. The main aims of the author are to teach the reader the basic principles of the method as well as to formulate consistent approximate models, leading to reasonably simple inverse problems. Containing an extensive bibliography, numerous practical and numerical examples as well as a detailed presentation of the nuts and bolts of the method based on the long-term experience of SNMR development and practical use, this book is useful for students, scientists and professional engineers working in the field of hydrogeophysics and hydrogeology. Contents 1. SNMR Imaging for Groundwater. 2. The Basics of NMR. 3. Forward Modeling. 4. Inversion. 5. Link Between SNMR and Aquifer Parameters.