A unique approach to solving HPLC problems. Everyone who bought «Problem Solving in HPLC» by Stavros Kromidas will equally benefit from nearly 100 new practical examples for optimization, trouble-shooting, and instrument performance given in this sequel. The author provides – guidance for selecting and evaluating methods, intstruments and columns, – practical help with everyday trouble-shooting, – advice for optimizing separations, always explaining the reason why. In each case the problem, the solution and the conclusions are presented over a maximum of 4 pages, and in addition the book contains manufacturers' addresses, references, data tables and checklists.