Many Canadians see the role their country's military plays in Afghanistan as an anomaly. However, this assumption is far from the truth. As U.S. Secretary of State Condoleezza Rice has commented, «Canadians are fierce fighters.» Fortune Favours the Brave certainly proves this point in a collection of essays that showcases the fighting spirit and courage of Canada's military. Daring actions featured in the book include the intrepid assault on the Fortress of Louisbourg and the cat-and-mouse struggle between Canadian partisans and Rogers's Rangers in the Seven Years' War in the 1750s; the seesaw battle for the Niagara frontier in the War of 1812; an innovative trench raid in the First World War; the valiant parachute assault to penetrate the Third Reich in the Second World War; the infamous battle at Kap'yong in the Korean War; covert submarine operations during the Cold War; the Medak Pocket clash in Croatia in the early 1990s; and Operation Medusa in Afghanistan.
The interactions of proteins with other molecules are important in many cellular activities. Investigations have been carried out to understand the recognition mechanism, identify the binding sites, analyze the the binding affinity of complexes, and study the influence of mutations on diseases. Protein interactions are also crucial in structure-based drug design. This book covers computational analysis of protein-protein, protein-nucleic acid and protein-ligand interactions and their applications. It provides up-to-date information and the latest developments from experts in the field, using illustrations to explain the key concepts and applications. This volume can serve as a single source on comparative studies of proteins interacting with proteins/DNAs/RNAs/carbohydrates and small molecules. Contents: Protein–Protein Interactions: Structural and Dynamical Aspects of Evolutionarily Conserved Protein–Protein Complexes (Himani Tandon, Sneha Vishwanath and Narayanaswamy Srinivasan) A Comprehensive Overview of Sequence-Based Protein-Binding Residue Predictions for Structured and Disordered Regions (Amita Barik and Lukasz Kurgan) Prediction of Protein–Protein Complex Structures by Docking (Danial Pourjafar-Dehkordi and Martin Zacharias) Binding Affinity of Protein–Protein Complexes: Experimental Techniques, Databases and Computational Methods (M Michael Gromiha) Mutational Effects on Protein–Protein Interactions (Jackson Weako, Attila Gursoy and Ozlem Keskin) Predicting the Consequences of Mutations (Hemant Kumar and Julia M Shifman) Protein–Nucleic Acid Interactions: Computational Approaches for Understanding the Recognition Mechanism of Protein–Nucleic Acid Complexes (Ambuj Srivastava, Dhanusha Yesudhas, A Kulandaisamy, Nisha Muralidharan, C Ramakrishnan, R Nagarajan and M Michael Gromiha) Prediction of Nucleic Acid Binding Proteins and Their Binding Sites (Dhanusha Yesudhas, Ambuj Srivastava, Nisha Muralidharan, A Kulandaisamy, R Nagarajan and M Michael Gromiha) Predicting Protein–Binding Sites in Nucleic Acids (Kyungsook Han) Docking Algorithms and Scoring Functions (Arina Afanasyeva, Chioko Nagao and Kenji Mizuguchi) Recent Progress of Methodology Development for Protein–RNA Docking (Yun Guo, Xiaoyong Pan and Hong-Bin Shen) Protein–Ligand Interactions: Protein–Carbohydrate Complexes: Binding Site Analysis, Prediction, Binding Affinity and Molecular Dynamics Simulations (K Veluraja, N R Siva Shanmugam, J Jino Blessy, R A Jeyaram, B Lalithamaheswari and M Michael Gromiha) Quantitative Structure-Activity Relationship in Ligand-Based Drug Design: Concepts and Applications (Vishnupriya Kanakaveti, P Anoosha, R Sakthivel, S K Rayala and M Michael Gromiha) Protein–Ligand Interactions in Molecular Modeling and Structure-Based Drug Design (Devadasan Velmurugan, Dasararaju Gayathri, Chandrasekaran Ramakrishnan and Atanu Bhattacharjee) An Overview of Protein–Ligand Docking and Scoring Algorithms (Ruchika Bhat, Abhilash Jayaraj, Anjali Soni and B Jayaram) Readership: Graduate students and researchers working on protein interactions; researchers in the fields of bioinformatics, computational biology, computational chemistry, biochemistry, biophysics.Protein Interactions;Binding Sites;Prediction;Structural Analysis;Recognition Mechanism;Computational Methods;Protein-protein;Protein-RNA;Protein-DNA;Protein-ligand;Binding Affinity;Mutation;Databases;Web Servers;QSAR;Docking;Molecular Dynamics;Drug Design0 Key Features: Single unique source with concepts and applications on all types of protein complexesWritten by outstanding researchers in the field with easily understandable illustrationsCompilation of databases and online toolsUp-to-date literature and latest developments
A look at gun control, campus sexual assault, immigration, and more that considers the future of responses to domestic violence Domestic violence is commonly assumed to be a bipartisan, nonpolitical issue, with politicians of all stripes claiming to work to end family violence. Nevertheless, the Violence Against Women Act expired for over 500 days between 2012 and 2013 due to differences between the U.S. Senate and House, demonstrating that legal protections for domestic abuse survivors are both highly political and highly vulnerable. Racial and gender politics, the move toward criminalization, reproductive justice concerns, gun control debates, and political interests are increasingly shaping responses to domestic violence, demonstrating the need for greater consideration of the interplay of politics, domestic violence, and how the law works in people’s lives. The Politicization of Safety provides a critical historical perspective on domestic violence responses in the United States. It grapples with the ways in which child welfare systems and civil and criminal justice responses intersect, and considers the different, overlapping ways in which survivors of domestic abuse are forced to cope with institutionalized discrimination based on race, gender, sexual orientation, and immigration status. The book also examines movement politics and the feminist movement with respect to domestic violence policies. The tensions discussed in this book, similar to those involved in the #metoo movement, include questions of accountability, reckoning, redemption, healing, and forgiveness. What is the future of feminism and the movements against gender-based violence and domestic violence? Readers are invited to question assumptions about how society and the legal system respond to intimate partner violence and to challenge the domestic violence field to move beyond old paradigms and contend with larger justice issues.
The impact of the U.S. immigration and legal systems on children and youth In the United States, millions of children are undocumented migrants or have family members who came to the country without authorization. The unique challenges with which these children and youth must cope demand special attention. Illegal Encounters considers illegality, deportability, and deportation in the lives of young people—those who migrate as well as those who are affected by the migration of others. A primary focus of the volume is to understand how children and youth encounter, move through, or are outside of a range of legal processes, including border enforcement, immigration detention, federal custody, courts, and state processes of categorization. Even if young people do not directly interact with state immigration systems—because they are U.S. citizens or have avoided detention—they are nonetheless deeply affected by the reach of the government in its many forms. Contributors privilege the voices and everyday experiences of immigrant children and youth themselves. By combining different perspectives from advocates, service providers, attorneys, researchers, and young immigrants, the volume presents rich accounts that can contribute to informed debates and policy reforms. Illegal Encounters sheds light on the unique ways in which policies, laws, and legal categories shape so much of daily life for young immigrants. The book makes visible the burdens, hopes, and potential of a population of young people and their families who have been largely hidden from public view and are currently under siege, following their movement through complicated immigration systems and institutions in the United States.
This book informs a renewed movement for fair lending and fair housing. Leading advocates and specialists examine strategic initiatives to realize objectives of the federal Fair Housing Act as well as state and local laws Well-known fair housing and fair lending activists and organizers examine the implications of the new wave of fair housing activism generated by Occupy Wall Street protests and the many successes achieved in fair housing and fair lending over the years. The book reveals the limitations of advocacy efforts and the challenges that remain. Best directions for future action are brought to light by staff of fair housing organizations, fair housing attorneys, community and labor organizers, and scholars who have researched social justice organizing and advocacy movements. The book is written for general interest and academic audiences. Contributors address the foreclosure crisis, access to credit in a changing marketplace, and the immoral hazards of big banks. They examine opportunities in collective bargaining available to homeowners and how low-income and minority households were denied access to historically low home prices and interest rates. Authors question the effectiveness of litigation to uphold the Fair Housing Act's promise of nondiscriminatory home loans and ask how the Consumer Financial Protection Bureau is assuring fair lending. They also look at where immigrants stand, housing as a human right, and methods for building a movement.
A luminous translation of Arabic tales of enchantment and wonder Translated into English for the very first time, A Hundred and One Nights is a marvelous example of the rich tradition of popular Arabic storytelling. Like the celebrated Thousand and One Nights , this collection opens with the frame story of Scheherazade, the vizier’s gifted daughter who recounts imaginative tales night after night in an effort to distract the murderous king from taking her life. A Hundred and One Nights features an almost entirely different set of stories, however, each one more thrilling, amusing, and disturbing than the last. Here, we encounter tales of epic warriors, buried treasure, disappearing brides, cannibal demon-women, fatal shipwrecks, and clever ruses, where human strength and ingenuity play out against a backdrop of inexorable, inscrutable fate. Distinctly rooted in Arabic literary culture and the Islamic tradition, these tales draw on motifs and story elements that circulated across cultures, including Indian and Chinese antecedents, and features a frame story possibly older than its more famous sibling. This vibrant translation of A Hundred and One Nights promises to transport readers, new and veteran alike, into its fantastical realms of magic and wonder.An English-only edition.
Insights into power, spectacle, and performance in the courts of Middle Eastern rulers In recent decades, scholars have produced much new research on courtly life in medieval Europe, but studies on imperial and royal courts across the Middle East have received much less attention, particularly for courts before 1500AD. In the Presence of Power, however, sheds new light on courtly life across the region. This insightful, exploratory collection of essays uncovers surprising commonalities across a broad swath of cultures. The pre-modern period in this volume includes roughly seven centuries, opening with the first dynasty of Islam, the Umayyads, whose reign marked an important watershed for Late Antique culture, and closing with the rule of the so-called “gunpowder” empires of the Ottomans and Safavids over much of the Near East in the sixteenth century. In between, this volume locates similarities across the Western Medieval, Byzantine and Islamicate courtly cultures, spanning a vast history and geography to demonstrate the important cross-pollinations that occurred between their literary and cultural legacies. This study does not presume the presence of one shared courtly institution across time and space, but rather seeks to understand the different ways in which contemporaries experienced and spoke about these places of power and performance. Adopting a very broad view of performances, In the Presence of Power includes exuberant expressions of love in Arabic stories, shadow plays in Mamluk Cairo, Byzantine storytelling, religious food traditions in Christian Cyprus, advice, and political and ethnographic performances of power.
A completely updated edition of a seminal work on fans and communities We are all fans. Whether we follow our favorite celebrities on Twitter, attend fan conventions such as Comic Con, or simply wait with bated breath for the next episode of our favorite television drama—each of us is a fan. Recognizing that fandom is not unusual, but rather a universal subculture, the contributions in this book demonstrate that understanding fans–whether of toys, TV shows, celebrities, comics, music, film, or politicians–is vital to an understanding of media audiences, use, engagement, and participatory culture in a digital age. Including eighteen new, original essays covering topics such as activism directed at racism in sports fandom, fan/producer interactions at Comic Con, the impact of new technologies on fandom, and the politics and legality of fanfic, this wide-ranging collection provides diverse approaches to fandom for anyone seeking to understand modern life in our increasingly mediated, globalized and binge-watching world.
An in-depth political, legal, and philosophical study into the implications of wealth inequality in modern societies. [b][/b]Wealth, and specifically its distribution, has been a topic of great debate in recent years. Calls for justice against corporations implicated in the 2008 financial crash; populist rallying against “the one percent”; distrust of the influence of wealthy donors on elections and policy—all of these issues have their roots in a larger discussion of how wealth operates in American economic and political life. In Wealth a distinguished interdisciplinary group of scholars in political science, law and philosophy address the complex set of questions that relate to economic wealth and its implications for social and political life in modern societies. The volume thus brings together a range of perspectives on wealth, inequality, capitalism, oligarchy, and democracy. The essays also cover a number of more specific topics including limitarianism, US Constitutional history, the wealth defense industry, slavery, and tax policy. Wealth offers analysis and prescription including original assessment of existing forms of economic wealth and creative policy responses for the negative implications of wealth inequality. Economic wealth and its distribution is a pressing issue and this latest installment in the NOMOS series offers new and thought provoking insights.
An indispensable collection that re-examines what it means to belong in the world. [b][/b]"Where are you from?" The word cosmopolitan was first used as a way of evading exactly this question, when Diogenes the Cynic declared himself a “kosmo-polites,” or citizen of the world. Cosmopolitanism displays two impulses—on the one hand, a detachment from one’s place of origin, while on the other, an assertion of membership in some larger, more compelling collective. Cosmopolitanisms works from the premise that there is more than one kind of cosmopolitanism, a plurality that insists cosmopolitanism can no longer stand as a single ideal against which all smaller loyalties and forms of belonging are judged. Rather, cosmopolitanism can be defined as one of many possible modes of life, thought, and sensibility that are produced when commitments and loyalties are multiple and overlapping. Featuring essays by major thinkers, including Homi Bhabha, Jean Bethke Elshtain, Thomas Bender, Leela Gandhi, Ato Quayson, and David Hollinger, among others, this collection asks what these plural cosmopolitanisms have in common, and how the cosmopolitanisms of the underprivileged might serve the ethical values and political causes that matter to their members. In addition to exploring the philosophy of Kant and the space of the city, this volume focuses on global justice, which asks what cosmopolitanism is good for, and on the global south, which has often been assumed to be an object of cosmopolitan scrutiny, not itself a source or origin of cosmopolitanism. This book gives a new meaning to belonging and its ground-breaking arguments call for deep and necessary discussion and discourse. An indispensable collection that re-examines what it means to belong in the world. [b][/b]"Where are you from?" The word cosmopolitan was first used as a way of evading exactly this question, when Diogenes the Cynic declared himself a “kosmo-polites,” or citizen of the world. Cosmopolitanism displays two impulses—on the one hand, a detachment from one’s place of origin, while on the other, an assertion of membership in some larger, more compelling collective. Cosmopolitanisms works from the premise that there is more than one kind of cosmopolitanism, a plurality that insists cosmopolitanism can no longer stand as a single ideal against which all smaller loyalties and forms of belonging are judged. Rather, cosmopolitanism can be defined as one of many possible modes of life, thought, and sensibility that are produced when commitments and loyalties are multiple and overlapping. Featuring essays by major thinkers, including Homi Bhabha, Jean Bethke Elshtain, Thomas Bender, Leela Gandhi, Ato Quayson, and David Hollinger, among others, this collection asks what these plural cosmopolitanisms have in common, and how the cosmopolitanisms of the underprivileged might serve the ethical values and political causes that matter to their members. In addition to exploring the philosophy of Kant and the space of the city, this volume focuses on global justice, which asks what cosmopolitanism is good for, and on the global south, which has often been assumed to be an object of cosmopolitan scrutiny, not itself a source or origin of cosmopolitanism. This book gives a new meaning to belonging and its ground-breaking arguments call for deep and necessary discussion and discourse.