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    Aboriginal Ontario

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    Winner of the 1995 Ontario Historical Society Joseph Brant Award for the best book on native studies Aboriginal Ontario: Historical Perspectives on the First Nations contains seventeen essays on aspects of the history of the First Nations living within the present-day boundaries of Ontario. This volume reviews the experience of both the Algonquian and Iroquoian peoples in Southern Ontario, as well as the Algonquians in Northern Ontario. The first section describes the climate and landforms of Ontario thousands of years ago. It includes a comprehensive account of the archaeologists' contributions to our knowledge of the material culture of the First Nations before the arrival of the Europeans. The essays in the second and third sections look respectively at the Native peoples of Southern Ontario and Northern Ontario, from 1550 to 1945. The final section looks at more recent developments. The volume includes numerous illustrations and maps, as well as an extensive bibliography.

    The Canoe in Canadian Cultures

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    The canoe is a symbol unique to Canada. One of the greatest gifts of First Peoples to all those who came after, the canoe is Canada's most powerful icon. Within this Canexus II publication are a collection of essays by paddling enthusiasts and experts. Contributing authors include: Eugene Arima, Shanna Balazs, David Finch, Ralph Frese, Toni Harting, Bob Henderson, Bruce W. Hodgins, Bert Horwood, Gwyneth Hoyle, John Jennings, Timothy Kent, Peter Labor, Adrian Lee, Kenneth R. Lister, Becky Mason, James Raffan, Alister Thomas and Kirk Wipper.

    Crime Where the Nights are Long

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    The period from the early 1880s through the First World War has been called «The Golden Age of the Storytellers.» These were the writers who sought not to write great literature, but to entertain, spinning yarns to be printed and read, just as their predecessors, the minstrels and bards, recited and were listened to. Through their countless tales of adventure and derring-do they brought romance and colour to the lives of those who could do no more than dream. This was the age of Sir Arthur Conan Doyle, H. Rider Haggard, Rudyard Kipling, Robert Louis Stevenson, and H.G. Wells. Canadian writers contributed in no small way to the cornucopia of romance and adventure the reading public could find at the newsstands and bookstores. This is the period of which Messrs Roper, Beharriell, and Scheider in Literary History of Canada: Canadian Literature in English (2d ed., 1976) say «the Canadian fiction-writers between 1880 and 1920 were read more widely by their contemporaries, inside and outside Canada, than have been the Canadian fiction-writers – collectively – since.» Literary historian David Skene-Melvin, the leading authority on Canadian criminous literature, has garnered from amongst the collections and magazines of the period a second anthology of stirring tales by Grant Allen, Robert Barr, Algernon Blackwood, W. H. Blake, Susan Carleton, William Henry Drummond, William Fraser, Harvey O’Higgins, Sir Gilbert Parker, Hesketh Pearson, Alan Sullivan, and others, some never before anthologized, guaranteed to set the blood a-racing and stimulate the imagination.

    The Canadian General Election of 2004

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    The Canadian General Election of 2004 is the definitive study of the campaign and the election. The 2004 edition includes analyses of: The campaigns of the 4 major parties and smaller partiesThe role of newspapers, television and the internet in the campaignsThe pre-election pollsVoting patterns across the countryThe rise in non-votingArticles are contributed from leading Canadian political writers, commentators and pollsters, including: Stephen Clarkson, Faron Ellis, and Peter Woolstencroft, Alan Whitehorn, Alain Gagnon, Susan Harada, Tamara Small, Christopher Waddell, Paul Attallah, Michael Marzolini, Andre Turcotte and Lawrence Leduc.

    Pike's Portage

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    "Pike’s Portage plays a very special role in the landscape of Canada’s Far North and its human history. It is both an ancient gateway and the funnel for early travel from the boreal forest of the Mackenzie River watershed to the vast open spaces of the subarctic taiga, better known as the «Barren Lands» of Canada. "This book is a rich and wonderful comopendium of stories about this area and the early white explorers, the Dene guides, the adventurers, the trappers, the misguided wanderers (like John Hornby) as well as the modern-day canoeists who passed this way. For the reader, it provides an absorbing escape into the past and the endless solitude of the northern wilderness." – George Luste, wilderness canoeist, physics professor (University of Toronto), and founder-organizer of the annual Wilderness Canoeing Symposium. "So why do people come to this place, this Pike’s Portage in particular? The call of landscape is potent and these word portraits collected here offer up some of those who have answered. Both subject and writer reveal the complexities of human perception. Some are called by the profound power of inherited cultural meaning, while a huge dose of imagination draws others from far away. These worlds seldom truly meet, even in a place as busy as this, but whether it is homeland or wilderness, human histories are recorded in footprints, place names, and memory, and here we stand with a magnificent view, marvelling at it all." – Susan Irving, Curatorial Assistant, Prince of Wales Northern Heritage Centre, Yellowknife, NWT

    Ontario's African-Canadian Heritage

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    Ontario’s African-Canadian Heritage is composed of the collected works of Professor Fred Landon, who for more than 60 years wrote about African-Canadian history. The selected articles have, for the most part, never been surpassed by more recent research and offer a wealth of data on slavery, abolition, the Underground Railroad, and more, providing unique insights into the abundance of African-Canadian heritage in Ontario. Though much of Landons research was published in the Ontario Historical Societys journal, Ontario History, some of the articles reproduced here appeared in such prestigious U.S. publications as the Journal of Negro History. This volume, illustrated and extensively annotated, includes research by the editors into the life of Fred Landon. It is the Legacy Project for the Bicentennial of the Abolition of the Atlantic Slave Trade, an initiative of the OHS, funded by a «Roots of Freedom» grant received from the Ontario Ministry of Citizenship and Immigration.

    Revisiting "Our Forest Home"

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    Frances Stewart arrived in Upper Canada from Ireland in 1822 with her husband, three children, and two servants. The family settled in Douro Township on the bank of the Otonabee River in 1823. Spanning three-quarters of a century, her letters represent the immigrant experience of one of the first pioneer women in the Peterborough, Ontario, area. Included are transcripts of the extant collection. They chronicle the three stages of Francess life: the years of her childhood in Ireland to her departure for North America; her voyage across the Atlantic and her life in Upper Canada to the time of her husbands death in 1847; and the period of widowhood until her death in 1872. The chapter summaries, annotations, and key passages extracted from letters written by others further the story of Francess nineteenth-century immigrant life. Advance Praise for Revisiting Our Forest Home Presenting the perspective of a cultivated immigrant who refrained from publication, Frances Stewarts articulate letters to her family and friends nicely complement the narratives of her Peterborough neighbours, Susanna Moodie and Catharine Parr Traill. Jodi Aokis intelligent approach to the editorial complexities of the Stewart archive has given us a reliable and welcome volume that makes an important contribution to our understanding of womens lives on the Upper-Canadian frontier. Carole Gerson, University Professor, English Department, Simon Fraser University Revisiting Our Forest Home is a welcome addition to the scholarly record of nineteenth-century writing and letters by immigrant gentlewomen to Upper Canada. To have this well-edited and thoughtful record of Stewarts struggles available is a boon to scholars, old and new. With precision and tenderness, Jodi Aoki brings forward these important and culturally revealing letters. In her hands, the original Our Forest Home, initially a project meant only for family members, becomes a valuable and much fuller record of social and family life in early Ontario. Michael Peterman, Professor Emeritus, Trent University, FRSC

    Sir Sandford Fleming

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    Sandford Fleming knew fame and many honours later in life, but the path was not always easy. His beginnings are revealed in these early diaries that record his thoughts as an eighteen-year-old leaving his family home in Scotland for Canada. After unsuccessful attempts to get work as a surveyor, he finally made important contacts in Toronto, and through involvement with the Mechanics' Institute and the (Royal) Canadian Institute, became connected to the leading architects and engineers in the community. His work on major projects, including an ambitious plan for the Toronto Harbour and The Esplanade, ultimately led to his first big railway appointment in 1852. Best known for his role in mapping the Canadian Pacific Railway, he also designed Canada's first adhesive postage stamp, the three-penny Beaver; was an early promoter of the Pacific cable; and is recognized around the world as the inventor of Standard Time. The recipient of many honours, Fleming was knighted by Queen Victoria in 1897.

    Fortune Favours the Brave

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    Many Canadians see the role their country's military plays in Afghanistan as an anomaly. However, this assumption is far from the truth. As U.S. Secretary of State Condoleezza Rice has commented, «Canadians are fierce fighters.» Fortune Favours the Brave certainly proves this point in a collection of essays that showcases the fighting spirit and courage of Canada's military. Daring actions featured in the book include the intrepid assault on the Fortress of Louisbourg and the cat-and-mouse struggle between Canadian partisans and Rogers's Rangers in the Seven Years' War in the 1750s; the seesaw battle for the Niagara frontier in the War of 1812; an innovative trench raid in the First World War; the valiant parachute assault to penetrate the Third Reich in the Second World War; the infamous battle at Kap'yong in the Korean War; covert submarine operations during the Cold War; the Medak Pocket clash in Croatia in the early 1990s; and Operation Medusa in Afghanistan.

    Protein Interactions

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    The interactions of proteins with other molecules are important in many cellular activities. Investigations have been carried out to understand the recognition mechanism, identify the binding sites, analyze the the binding affinity of complexes, and study the influence of mutations on diseases. Protein interactions are also crucial in structure-based drug design. This book covers computational analysis of protein-protein, protein-nucleic acid and protein-ligand interactions and their applications. It provides up-to-date information and the latest developments from experts in the field, using illustrations to explain the key concepts and applications. This volume can serve as a single source on comparative studies of proteins interacting with proteins/DNAs/RNAs/carbohydrates and small molecules. Contents: Protein–Protein Interactions: Structural and Dynamical Aspects of Evolutionarily Conserved Protein–Protein Complexes (Himani Tandon, Sneha Vishwanath and Narayanaswamy Srinivasan) A Comprehensive Overview of Sequence-Based Protein-Binding Residue Predictions for Structured and Disordered Regions (Amita Barik and Lukasz Kurgan) Prediction of Protein–Protein Complex Structures by Docking (Danial Pourjafar-Dehkordi and Martin Zacharias) Binding Affinity of Protein–Protein Complexes: Experimental Techniques, Databases and Computational Methods (M Michael Gromiha) Mutational Effects on Protein–Protein Interactions (Jackson Weako, Attila Gursoy and Ozlem Keskin) Predicting the Consequences of Mutations (Hemant Kumar and Julia M Shifman) Protein–Nucleic Acid Interactions: Computational Approaches for Understanding the Recognition Mechanism of Protein–Nucleic Acid Complexes (Ambuj Srivastava, Dhanusha Yesudhas, A Kulandaisamy, Nisha Muralidharan, C Ramakrishnan, R Nagarajan and M Michael Gromiha) Prediction of Nucleic Acid Binding Proteins and Their Binding Sites (Dhanusha Yesudhas, Ambuj Srivastava, Nisha Muralidharan, A Kulandaisamy, R Nagarajan and M Michael Gromiha) Predicting Protein–Binding Sites in Nucleic Acids (Kyungsook Han) Docking Algorithms and Scoring Functions (Arina Afanasyeva, Chioko Nagao and Kenji Mizuguchi) Recent Progress of Methodology Development for Protein–RNA Docking (Yun Guo, Xiaoyong Pan and Hong-Bin Shen) Protein–Ligand Interactions: Protein–Carbohydrate Complexes: Binding Site Analysis, Prediction, Binding Affinity and Molecular Dynamics Simulations (K Veluraja, N R Siva Shanmugam, J Jino Blessy, R A Jeyaram, B Lalithamaheswari and M Michael Gromiha) Quantitative Structure-Activity Relationship in Ligand-Based Drug Design: Concepts and Applications (Vishnupriya Kanakaveti, P Anoosha, R Sakthivel, S K Rayala and M Michael Gromiha) Protein–Ligand Interactions in Molecular Modeling and Structure-Based Drug Design (Devadasan Velmurugan, Dasararaju Gayathri, Chandrasekaran Ramakrishnan and Atanu Bhattacharjee) An Overview of Protein–Ligand Docking and Scoring Algorithms (Ruchika Bhat, Abhilash Jayaraj, Anjali Soni and B Jayaram) Readership: Graduate students and researchers working on protein interactions; researchers in the fields of bioinformatics, computational biology, computational chemistry, biochemistry, biophysics.Protein Interactions;Binding Sites;Prediction;Structural Analysis;Recognition Mechanism;Computational Methods;Protein-protein;Protein-RNA;Protein-DNA;Protein-ligand;Binding Affinity;Mutation;Databases;Web Servers;QSAR;Docking;Molecular Dynamics;Drug Design0 Key Features: Single unique source with concepts and applications on all types of protein complexesWritten by outstanding researchers in the field with easily understandable illustrationsCompilation of databases and online toolsUp-to-date literature and latest developments