Catalytic reductions are among the most used synthetic transformations, and the past 15 years have seen great progress in this field. Science of Synthesis: Catalytic Reduction in Organic Synthesis includes the latest developments, as well as selective coverage of more well-established methods. Both heterogeneous and homogeneous catalytic systems are covered, and enantioselective methodology is well represented. There is a focus on the use of metal nanoparticles, both in suspension as well as on solid supports. Furthermore, the advent of research on the conversion of renewable resources into fuels and chemicals has given a great impetus to the field, as deoxygenations are often the first step in the conversion of biomass and this can often be achieved using hydrogenation or hydrogenolysis reactions. Scope, limitations, and mechanism of the reactions are discussed and key experimental procedures are included.
Renowned spine experts share recent advances on the management of spinal infections AOSpine Masters Series, Volume 10: Spinal Infections is a concise, state-of-the-art review covering all aspects of spinal infections – from basic science and epidemiology to fundamental surgical and nonsurgical approaches. Internationally renowned spine surgeons Luis Roberto Vialle, S. Rajasekaran, Rishi Kanna, Giuseppe Barbagallo, and many experts across the world, provide clinical pearls and insights gleaned from years of hands-on expertise. This book provides discussion of underlying pathologies, imaging and diagnosis, and surgical techniques, with a focus on issues specific to children, co-infection with HIV, postoperative problems, geriatric patients, and pseudoarthrosis. Key Highlights Overviews on the epidemiology, microbiology, and pathology of spinal infectionsDetailed review of imaging, and other investigationsTreatment planning and surgical techniquesRisk stratification and prevention of post-operative infectionPathogenesis, clinical features, diagnosis, and treatment of pyogenic spondylodiscitis in various regions of the spineClinical pearls on the management of spinal tuberculosis, including drug therapy and surgery The AOSpine Masters series, a co-publication of Thieme and the AOSpine Foundation, addresses current clinical issues featuring international masters sharing their expertise in the core areas in the field. The goal of the series is to contribute to an evidence-based approach to spine care. This textbook is essential reading for all spine surgeons. Orthopaedic and neurosurgery residents, as well as veteran surgeons will find this a useful tool for daily practice.
Long heralded as a key guide for medical students, nurses, and allied health professionals, the Essentials of Clinical Examination Handbook, Eighth Edition is a concise yet comprehensive on-the-job reference for history-taking and physical examination, which covers both standard exams and specialty-specific diagnostic approaches. The Handbook has been edited by over 70 students and 60 faculty experts at the University of Toronto. This new edition includes improved evidence-based clinical pearls and succinct summary tables for differential diagnoses and clinical presentations. A companion mobile application has also been developed which features clinical examination checklists that users can use to practice and test themselves on the go. This edition marks its 20th anniversary as a concise, portable, and affordable guide to clinical examination for medical students and allied health professions around the world.
Master spine surgeons Alexander R. Vaccaro, Richard G. Fessler, and a cadre of esteemed co-editors have compiled the most comprehensive textbook to date detailing minimally invasive spine (MIS) versus open spine surgery techniques. Controversies in Spine Surgery, MIS versus OPEN: Best Evidence Recommendations features debates by renowned experts on one of the most provocative topics in spine surgery. Twenty-four chapters systematically organized into four sections — degenerative, trauma, tumor, and other issues, cover procedures and underlying pathologies, backed by a large, diverse body of literature. MIS and open approaches are thoroughly compared and contrasted in each chapter. Evidence is presented and analyzed in an objective manner with 'opposing sides' presenting differing opinions and techniques, resulting in a synchronous collection of pros and cons. Every chapter is masterfully summed up by the book's editors — each of whom have varying stances on the topics at hand. This unique 'duel' and 'duet' discussion enables readers to assimilate information, benefit from the balanced harmony between divergent opinions, and reach their own conclusions. Key HighlightsComparative risks, benefits, complications, and outcomes for a full spectrum of lumbar, thoracic and cervical proceduresMIS versus open approaches for lumbar stenosis, synovial cysts, lumbar adjacent segment degeneration, degenerative scoliosis, flatback syndrome, thoracic disc herniation, and dural tearsTumor resection and stabilization, quality of life issues, and potential advantages and risks of MIS techniquesKey differences in MIS versus open operations such as radiation exposure and costsAnalysis of 3-D navigational imaging to improve outcomes and reduce radiation exposure and operating time This book is a tremendous, evidence-based tool to guide spine surgeons as they make important decisions on selecting the most optimal spine surgery techniques. It is a must-have resource for all resident and veteran orthopaedic surgeons and neurosurgeons who specialize in treating patients with spine conditions. Alexander R. Vaccaro, MD, PhD, FACS, MBA, is Richard H. Rothman Professor and Chairman, Department of Orthopaedic Surgery, and Professor of Neurosurgery, Thomas Jefferson University and Hospitals; and President, The Rothman Institute, Philadelphia, Pennsylvania, USA. Richard G. Fessler, MD, PhD, is Professor, Department of Neurosurgery, Rush University Medical Center, Chicago, Illinois, USA. Faheem A. Sandhu, MD, PhD, is Professor of Neurosurgery, Director of Spine Surgery, and Co-Director, Center for Minimally Invasive Spine Surgery, Department of Neurosurgery, MedStar Georgetown University Hospital, Washington, DC, USA. Jean-Marc Voyadzis, MD, is Co-Director, Center for Minimally Invasive Spine Surgery and Associate Professor of Neurosurgery, MedStar Georgetown University Hospital, Washington, DC, USA. Jason C. Eck, DO, MS, is an Orthopaedic Spine Surgeon, Center for Sports Medicine and Orthopedics, Chattanooga, Tennessee, USA. Christopher K. Kepler, MD, MBA, is an Associate Professor and Orthopaedic Spine Surgeon, Department of Orthopaedic Surgery, Thomas Jefferson University and Hospitals, and The Rothman Institute, Philadelphia, Pennsylvania, USA. An award-winning international medical and scientific publisher, Thieme has demonstrated its commitment to the highest standard of quality in the state-of-the-art content and presentation of all its products. Founded in 1886, the Thieme name has become synonymous with high quality and excellence in online and print publishing.
Highly Commended by the BMA Medical Book Awards for Internal Medicine! Written and edited by internationally renowned specialists, the third edition of Gastroenterological Endoscopy covers the entire spectrum of diagnostic and therapeutic procedures for the upper and lower GI tract while providing the latest overview of GI disorders. A great wealth of high-resolution photographs provides the visual information needed to confidently assess and diagnose mucosal lesions of the entire digestive tract. Significant advances in the field—both medical and technical—since the last edition are covered in comprehensive detail. Key Features: New panel of top international editors, continuing the tradition of excellence, depth, and breadth as originated by founding editors Classen, Tytgat, and Lightdale; list of contributing authors is a «who's who» of GI endoscopyCoverage of newest, advanced tools and techniques: gastric-POEMS, submucosal tunnel endoscopic resection (STER), lumen-apposing metal stents, «over-the-scope» clips, and much moreMore than 750 exquisite images Gastroenterological Endoscopy , third edition, surely deserves a prominent place in any complete endoscopy reference collection.
Innovative strategies for artfully blending aesthetic techniques to maximize results The Art of Combining Surgical and Nonsurgical Techniques in Aesthetic Medicine by Julius W. Few Jr. reflects multidisciplinary contributions from renowned practitioners in plastic surgery, dermatology, oculoplastics, and facial plastic surgery. This is the first book to specifically discuss minimally-invasive aesthetic techniques for the face and body and how to strategically combine them, both with and without surgery. The text is rooted in evidence-based scientific principles and sound clinical applications, with the goal of helping aesthetic practitioners attain more favorable and longer-lasting results. Fifteen comprehensive chapters reflect the visionary beliefs of top experts in cosmetic medicine. Each topic is discussed by clinicians who have developed innovative approaches that will revolutionize the field. The book lays a solid foundation with opening chapters on concepts of beauty and nonsurgical facial rejuvenation in traditional surgical candidates. Subsequent chapters discuss innovative, combined approaches for both the face and body. Key FeaturesBlending and sequencing of techniques, and diverse skin type considerationsA wide array of modalities — from noninvasive devices, microneedling and platelet-rich plasma, and light- and energy-based therapies — to surgical interventionsPractical, real-life case studies throughoutMore than 200 detailed photos and colorful illustrations detail anatomy and approachesTechnical videos available online demonstrate techniques in depthSpecial emphasis on how to avoid and treat complications This must-have resource masterfully guides novice and veteran clinicians alike on the thoughtful use of combined state-of-the-art techniques to achieve optimal outcomes. It will help plastic surgeons, facial plastic surgeons, dermatologists, and dermatologic surgeons reduce recovery time and enhance results in their patients. Julius W. Few Jr., MD, is Director, The Few Institute for Aesthetic Plastic Surgery, and Clinical Professor, Department of Surgery, Division of Plastic Surgery, University of Chicago Pritzker School of Medicine; and Health Science Clinician, Division of Plastic Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA. An award-winning international medical and scientific publisher, Thieme has demonstrated its commitment to the highest standard of quality in the state-of-the-art content and presentation of all its products. Founded in 1886, the Thieme name has become synonymous with high quality and excellence in online and print publishing.
Presenting essential topics in aesthetic and reconstructive surgery, this second edition of the bestselling Essentials of Plastic Surgery has been totally revised and updated to reflect substantial advances in this dynamic specialty. Coverage includes aesthetic surgery, face lift, neck lift, fillers, and breast augmentation along with reconstructive topics such as wound healing and microsurgery. This edition contains the work of many new contributors as well as several new chapters, including: Fundamentals of Perforator FlapsVascularized Composite Allografts and Transplant ImmunologyNegative Pressure Wound TherapySurgical Treatment of Migraine HeadachesFace TransplantationAugmentation-MastopexyNipple-Areolar ReconstructionFoot UlcersLymphedemaDistal Radius FracturesHand TransplantationFacial AnalysisFat GraftingThis second edition retains its seven-part structure as well as the familiar bullet point style, format, and pocket size that made the first edition so successful. References have been updated and significant additions have been made to graphics, including tables, charts, and illustrations. An eBook version is included with the print book.
The Science of Synthesis Editorial Board, together with the volume editors and authors, is constantly reviewing the whole field of synthetic organic chemistry as presented in Science of Synthesis and evaluating significant developments in synthetic methodology. Four annual volumes updating content across all categories ensure that you always have access to state-of-the-art synthetic methodology.
The field of N-heterocyclic carbenes, whether in transition-metal catalysis or organocatalysis, is rapidly evolving towards applications, but is also still very active on the catalyst development front. Significant advances have been made over the past two decades and the development of these reactions has dramatically improved the efficiency of organic synthesis. N-Heterocyclic carbene based catalysts are now widely applied in the area of synthesis of both natural products and therapeutic agents. Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis presents the most commonly used and significant metal- or non-metal-catalyzed reactions for modern organic synthesis. The basic principles and current state-of-the-art of the methods are covered. Scope, limitations, and mechanism of these reactions are discussed and key experimental procedures are included. Typical examples of target synthesis are often provided to show the utility and inspire further applications.
Endoscopic technology has advanced to the point where practitioners can now access, visualize, and treat spine pathologies previously only accessible through open surgical approaches. Endoscopic Spine Surgery 2nd Edition provides a comprehensive background on endoscopic spine surgery and covers an unparalleled number of minimally invasive spine procedures that have revolutionized the spine treatment paradigm. Readers will greatly benefit from many years of expertise and wisdom shared by master spine surgeons Daniel Kim, Gun Choi, Sang-Ho Lee, and Richard Fessler, and their expert contributors. Due to the narrow endoscopic view, subtle microanatomical differences in the lumbar, thoracic, and cervical regions are not always easy to visually discern. To address this challenge, the book contains detailed procedural descriptions and images mirroring endoscopic views spine surgeons encounter in the OR. Organized anatomically, 53 chapters guide readers systematically through lumbar, thoracic, cervical, and craniocervical junction procedures for pathologies ranging from low back pain and deformities to tumors, lesions, infections, and trauma. Key Features More than 1000 high quality images including color procedural photographs and medical illustrations provide in-depth visual understanding.Spinal pathologies and procedures delineated in 75 videos accessible via the Media Center – from case studies to step-by-step technique tutorials.Covers the full spectrum of spine endoscopy including percutaneous approaches, microdiscectomy, laminectomy, discectomy foraminotomy, hemilaminectomy, thoracic decompressions, fusion, fixation, and thoracoscopic procedures.The use of state-of-the-art technology such as ultrasonic bone dissectors, endoscopic radiofrequency denervation, the video telescope operating monitor (VITOM), minimally invasive tubular retractors, and 3D stereo-tubular endoscopic systems.Neurosurgical and orthopaedic residents, spine fellows, and seasoned spine surgeons will all greatly benefit from the significant knowledge and insights revealed in this remarkable multimedia resource. This book may also be of interest to neurosurgical and orthopaedic nurses, physical therapists, chiropractors, and medical device professionals.