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    Science of Synthesis: Flow Chemistry in Organic Synthesis

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    The aim of this work is to convey the practice, power, and potential of flow chemistry to a larger audience. An emerging and strengthening trend is that flow chemistry is much more than the adaption of batch processes to flow systems. Rather, flow chemistry offers a new paradigm in the way we think about chemical synthesis. This volume demonstrates the enabling power of continuous flow to access new reaction types and different chemistry space and, to this end, it has been compiled by a team of pioneers and leaders, who present both the practical and conceptual aspects of this rapidly growing field. Included are the principles of reactor design, automation, and separations/purifications in flow systems, applications in photochemistry, electrochemistry, gaseous systems, immobilized reagents and catalysts, and multistep processes. The synthesis of peptides, carbohydrates, and pharmaceuticals is covered and several chapters give insight into the use of flow in an industrial context.

    Science of Synthesis: Knowledge Updates 2018/4

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    The Science of Synthesis Editorial Board, together with the volume editors and authors, is constantly reviewing the whole field of synthetic organic chemistry as presented in Science of Synthesis and evaluating significant developments in synthetic methodology. Several annual volumes updating content across all categories ensure that you always have access to state-of-the-art synthetic methodology.

    Hernia Surgery

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    All the latest trends and technical innovations for both routine and complex hernia repair Surgical procedures to repair hernias are among the most common procedures of all, with a history going back over 200 years. While most procedures are routine, they can be a challenge, particularly when previous surgery in the area has caused scarring that distorts the anatomy. All currently established operative techniques are described and explained in detail in the book and illustrated, step by step, with a wealth of brilliant figures and diagrams. A detailed description of laparoscopic anatomy and preperitoneal procedures is given. Important information regarding indications and postoperative care is provided. New surgical treatment concepts for hernia arising in the early 21st century and expounded in this book include tension-free principles, inguinal hernia repair under local anesthesia, use of the preperitoneal space, and laparoscopic hernia repair. Key Features 3D mesh and patch-and-plug procedures Laparoscopic methods such as the single-port technique and mini-techniqueNew developments in open and laparoscopic surgery of incisional herniasSpecial disorders such as sports herniaRichly illustrated with hundreds of exquisite artist renderings Ideal for all surgeons in training, and of benefit to experienced surgeons as well, Schumpelick's Hernia Surgery is a complete introduction to evidence-based techniques in this field.

    An Anatomic Approach to Minimally Invasive Spine Surgery

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    Learn state-of-the-art MIS techniques from master spine surgeons! Significant advances have been made in minimally invasive spine (MIS) surgery approaches, techniques, and innovative technologies. By preserving normal anatomic integrity during spine surgery, MIS approaches enable spine surgeons to achieve improved patient outcomes, including faster return to normal active lifestyles and reduced revision rates. Exposing only the small portion of the spine responsible for symptoms via small ports or channels, requires a deep understanding of spinal anatomy and spinal pathophysiology. Building on the widely acclaimed first edition, An Anatomic Approach to Minimally Invasive Spine Surgery, Second Edition , provides an expanded foundation of knowledge to master minimally invasive spine surgery. World-renowned spine neurosurgeons Mick Perez-Cruet, Richard Fessler, Michael Wang, and a cadre of highly regarded spine surgery experts provide masterful tutorials on an impressive array of cutting-edge technologies. Organized by seven sections and 51 chapters, the book presents a diverse spectrum of current safe and efficacious MIS procedures and future innovations. Nonsurgical approaches include injection-based spine procedures and stereotactic radiosurgery. Surgical technique chapters discuss MIS anterior, posterior, and lateral approaches to the cervical, thoracic, and lumbar spine, with procedures such as endoscopic microdiscectomy, vertebroplasty and kyphoplasty, percutaneous instrumentation, and robotic spine surgery. Key Features Step-by-step illustrations, including more than 400 depictions by master surgical and anatomic illustrator Anthony Pazos portray the surgeon's-eye-view of anatomy, intraoperative images, and surgical instruments, thereby aiding in the understanding of anatomy and procedures20 online videos feature real-time operative fluoroscopy, pertinent anatomy, operative set-up, and common cervical, thoracic, and lumbar approachesDiscussion of novel MIS techniques reflected in 16 new or expanded chapters, including Robotic Assisted Thoracic Spine Surgery and Stem-Cell Based Intervertebral Disc Restoration There is truly no better clinical reward for spine surgeons than giving patients suffering from debilitating spinal disorders their life back. This quintessential MIS surgery resource will help surgeons and clinicians accomplish that goal.

    RadCases Plus Q&A Neuro Imaging

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    Essential neuroradiology cases and board-type Q&A review to help you pass your exam! Neuro Imaging Second Edition from Roy Riascos, Eliana Bonfante, and Susana Calle features 100 new cases along with two board-type multiple choice questions for each. This latest edition features state-of-the-art imaging technologies including perfusion techniques, spectroscopy, nuclear medicine, and 3D reconstructions. Updated and new classification systems have been integrated into brain tumor, traumatic spine injury, and intracranial aneurysm cases. For maximum ease of self-assessment, each case begins with the clinical presentation on the right-hand page; study that and then turn the page for imaging findings, differential diagnoses with the definitive diagnosis, essential facts, pearls and pitfalls, and more. Key Features New to this edition, a question-and-answer section for each case reinforces key conceptsEasy-to-read bulleted formatting and concise, point-by-point presentation of the Essential Facts enables learning and retention of high-yield facts and skill-building in neuroradiologic diagnosisOnline access to additional cases enables residents to arrange study sessions, quickly extract and master information, and prepare for specialized neuroradiology conferences Thieme's RadCases means cases selected to simulate what you will see on your exams, rounds, and rotations. RadCases helps you to identify the correct differential diagnosis for each case, including the most critical.The series comprehensively covers the following specialties:Breast Imaging · Cardiac Imaging · Emergency Imaging · Gastrointestinal Imaging · Genitourinary Imaging · Head and Neck Imaging · Interventional Radiology · Musculoskeletal Radiology · Neuro Imaging · Nuclear Medicine · Pediatric Imaging · Thoracic Imaging · Ultrasound Imaging Each RadCases second edition has a code allowing you one year of access to Thieme's online database of 350 cases: the 100 cases in this book plus 250 cases more. Master your cases, pass your exams, and diagnose with confidence: RadCases !

    Osteoporotic Fracture Care

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    With an increase in the longevity of the global population, care of the functional, cognitive, and physical health of older adults is essential. The dramatic demographic shift toward a growing aging population and an increase in osteoporotic fractures that has occurred over the last few decades especially in Western countries, has clearly shown the need for a comprehensive approach to treating fragility fractures by surgeons, geriatricians, and care staff. Osteoporotic Fracture Care: Medical and Surgical Management is the first book of its kind to offer a well-rounded and comprehensive resource on fragility fractures and orthogeriatric care designed to help new and experienced surgeons, geriatricians, physicians, and care personnel to better work together and develop interprofessional and interdisciplinary systems so as to treat patients more effectively. The book contains 44 chapters and is divided into three sections: «Principles,» «Improving system of care,» and the case-based part «Decision making and special considerations in surgical care.» The book's key features are:In-depth insight into the needs of older adults and how to best improve patient care, patient outcome, and reduce system costs.Twenty detailed and illustrative case-based chapters giving the reader a wide array of options to improve the patient care and outcomes.More than 1,000 high-quality x-rays, clinical images, and illustrations.Print book comes with bundled ebook.

    Eyelid & Periorbital Surgery

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    I found this up-to-date factual book to be well-written and relatively concise…Its easy readability will make it both appealing and useful for students, trainees, and experts. – PMFA News …there are 80 aesthetic and reconstructive oculoplastic videos, 30 of which are new, which makes this a one-of-a-kind video library. What I liked about the videos, especially the new ones, is the high quality, clarity, and details of technique provided by the authors who do the voiceovers themselves. – Plastic and Reconstructive Surgery FIRST PRIZE from the BMA Medical Book Awards for Surgical Specialties! Eyelid & Periorbital Surgery offers expansive coverage of aesthetic and reconstructive procedures in oculoplastic surgery. Oculoplastic and plastic surgeons combine their talents in this unique two-volume clinical resource that features comprehensive guidance for solving both common and rare eyelid and periorbital problems. With more than 2,900 photos and color illustrations, this edition has 26 rewritten first edition chapters and expands on an additional 13 new chapters, including topics ranging from nonsurgical periorbital rejuvenation to male blepharoplasty. Best of all, there are more than 30 new surgical videos demonstrating the latest surgical techniques. Also included is a complimentary eBook. Divided into 5 sections, the book begins by covering the fundamentals including periorbital and eyelid anatomy, eyelid function, innervation, biomechanics, and tissue grafts. The following section discusses aesthetic surgery including procedures such as brow lift, upper and lower blepharoplasty, midface lift, treatment of malar bags and festoons, lateral canthal dysfunction, and management of chemosis. A new section has been added on aesthetic nonsurgical state-of-the-art periorbital treatments with an update on injectable fillers, botulinum toxin injections, and fat grafting. The reconstructive surgery section covers ptosis surgery, upper and lower eyelid reconstruction, entropion and ectropion reconstruction, surgery for facial paralysis, malignant eyelid tumors, Graves' disease, and the treatment of pediatric patients. The new final section covers orbital and lacrimal surgery including blowout fracture of the orbital floor, neuroophthalmologic injuries, evisceration and enucleation, late repair of orbital fractures, and management of the lacrimal system. Step-by-step descriptions and detailed videos provide a wide variety of tips, clinical pearls, and personal insights from the authors making this an invaluable resource for surgeons interested in the topic.

    Science of Synthesis Knowledge Updates: 2018/3

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    The Science of Synthesis Editorial Board, together with the volume editors and authors, is constantly reviewing the whole field of synthetic organic chemistry as presented in Science of Synthesis and evaluating significant developments in synthetic methodology. Four annual volumes updating content across all categories ensure that you always have access to state-of-the-art synthetic methodology.

    Science of Synthesis Knowledge Updates: 2018/2

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    The Science of Synthesis Editorial Board, together with the volume editors and authors, is constantly reviewing the whole field of synthetic organic chemistry as presented in Science of Synthesis and evaluating significant developments in synthetic methodology. Several annual volumes updating content across all categories ensure that you always have access to state-of-the-art synthetic methodology.

    Science of Synthesis: Catalytic Reduction in Organic Synthesis Vol. 2

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    Catalytic reductions are among the most used synthetic transformations, and the past 15 years have seen great progress in this field. Science of Synthesis: Catalytic Reduction in Organic Synthesis includes the latest developments, as well as selective coverage of more well-established methods. Both heterogeneous and homogeneous catalytic systems are covered, and enantioselective methodology is well represented. There is a focus on the use of metal nanoparticles, both in suspension as well as on solid supports. Furthermore, the advent of research on the conversion of renewable resources into fuels and chemicals has given a great impetus to the field, as deoxygenations are often the first step in the conversion of biomass and this can often be achieved using hydrogenation or hydrogenolysis reactions. Scope, limitations, and mechanism of the reactions are discussed and key experimental procedures are included.