Группа авторов
Список книг автора Группа авторовDrugs
Statistics show that out of five thousand compounds with initial promise, five will go into human clinical trials, and only one will become an approved drug. This tiny fraction illustrates the huge complexities involved in bringing a drug to market, a process that brings together scientific research, medical ethics, business, and various regulatory agencies. Drugs-From Discovery to Approval presents a clear, step-by-step overview of the entire process. Using simple language, this comprehensive guide introduces basic concepts, then moves on to discuss disease target selection and the discovery processes for both small and large molecule drugs. Subsequent chapters explain preclinical studies, clinical trials, regulatory issues, good manufacturing practices (GMPs), and perspectives on the future. Coverage also includes: * A helpful listing of current FDA and European guidelines * A special section on regulatory authorities and processes in Japan and China * Rich illustrations throughout, including more than ninety figures and tables * Useful appendices on the history of drug discovery and development * Representative examples of drug mechanisms in action Written for professionals in the pharmaceutical industry, and readily accessible for students of pharmacy or medicine and others interested in drug discovery, Drugs-From Discovery to Approval represents a practical and approachable reference on this important process.
Psychopharmacology
Describes the latest advances in psychopharmacology – one of the most rapidly developing fields in modern science. This latest edition has been updated to cover new developments in drug therapy and research including newly introduced antipsychotics, antidepressants and antidementia drugs. Sections on the treatment of depression and dementia have been revised to include new developments in treatment strategies. It will be welcomed for its essentially clinical and psychological approach to modern pharmaceuticals, their therapeutic uses and limitations, adverse reactions and future directions for research.
Biopharmaceuticals
The latest edition of this highly acclaimed textbook, provides a comprehensive and up-to-date overview of the science and medical applications of biopharmaceutical products. Biopharmaceuticals refers to pharmaceutical substances derived from biological sources, and increasingly, it is synonymous with 'newer' pharmaceutical substances derived from genetic engineering or hybridoma technology. This superbly written review of the important areas of investigation in the field, covers drug production, plus the biochemical and molecular mechanisms of action together with the biotechnology of major biopharmaceutical types on the market or currently under development. There is also additional material reflecting both the technical advances in the area and detailed information on key topics such as the influence of genomics on drug discovery.
Pharmacoepidemiology
The fourth edition of Pharmacoepidemiology is an outstanding and fully comprehensive textbook, which will be an essential resource for all interested in the field—in academia, in regulatory agencies, in industry and in the law. Brian Strom’s classic textbook continues both to reflect the increased maturation of pharmacoepedemiology and to help shape it’s direction. Reviews of previous editions of his celebrated textbook include: «The book is essential reading for anyone interested in pharmacoepidemiology.» INTERNATIONAL JOURNAL OF EPIDEMIOLOGY “…an excellent textbook and a comprehensive reference which belongs in the library of every pharmaceutical manufacturer and regulator." EUROPEAN JOURNAL OF PUBLIC HEALTH
Beer
This important and extremely interesting book is a serious scientific and authoritative overview of the implications of drinking beer as part of the human diet. Coverage includes a history of beer in the diet, an overview of beer production and beer compositional analysis, the impact of raw materials, the desirable and undesirable components in beer and the contribution of beer to health, and social issues. Written by Professor Charlie Bamforth, well known for a lifetime's work in the brewing world, Beer: Health and Nutrition should find a place on the shelves of all those involved in providing dietary advice.
Dementia
Our perceptions of dementia and what dementia care should constitute have changed dramatically over the past 20 years. Research has uncovered a mass of information concerning all aspects of dementia. This wealth of information should be reflected in a dramatic change, indeed a metamorphosis, in the way people with dementia are cared for. No such change has occurred. Dementia – Metamorphosis in Care will address the need for change and provide practitioners with a means of understanding why adhering to the old model – the medical approach – can be damaging in current care settings. Practitioners are advised on what is needed from them in order that they can positively influence the lives of those living with dementia. The importance of the role of professional carer and the responsibility they carry regarding whether or not care improves, is underlined throughout the book.
Formulation and Analytical Development for Low-Dose Oral Drug Products
There are unique challenges in the formulation, manufacture, analytical chemistry, and regulatory requirements of low-dose drugs. This book provides an overview of this specialized field and combines formulation, analytical, and regulatory aspects of low-dose development into a single reference book. It describes analytical methodologies like dissolution testing, solid state NMR, Raman microscopy, and LC-MS and presents manufacturing techniques such as granulation, compaction, and compression. Complete with case studies and a discussion of regulatory requirements, this is a core reference for pharmaceutical scientists, regulators, and graduate students.
Managing your Patients' Data in the Neonatal and Pediatric ICU
With accompanying software! Clinicians manage a lot of data – on assorted bits of paper and in their heads. This book is about better ways to manage and understand large amounts of clinical data. Following on from his ground breaking book, Evaluating the Processes of Neonatal Intensive Care, Joseph Schulman has produced this eminently readable guide to patient data analysis. He demystifies the technical methodology to make this crucial aspect of good clinical practice understandable and usable for all health care workers. Computer technology has been relatively slow to transform the daily work of health care, the way it has transformed other professions that work with large amounts of data. Each day, we do our work as we did it the day before, even though current technology offers much better ways. Here are much better ways to document and learn from the daily work of clinical care. Here are the principles of data management and analysis and detailed examples of how to implement them using computer technology. To show you that the knowledge is scalable and useful, and to get you off to a running start, the book includes a complete point of care database software application tailored to the neonatal intensive care unit (NICU). With examples from the NICU and the pediatric ward, this book is aimed specifically at the neonatal and pediatric teams. The accompanying software can be downloaded on to your system or PDA, so that continual record assessment becomes second nature – a skill that will immeasurably improve practice and outcomes for all your patients.
Artful Therapy
Use the therapeutic potential of art to make progress in your practice Artful Therapy shows you how to use art to make a difference in therapy. Using visual imagery and art creation, you can help people with medical problems understand how they feel about their illness; victims of abuse «tell without talking»; and substance abuse and eating disorder clients tap into unresolved issues. These are just a few examples of how the power of art can improve your practice. Ideal for mental health professionals and allied workers with little or no art background, this accessible and proven guide takes you through the techniques of using art and visual imagery, and shows you how they can benefit clients of varying ages and abilities. With the art therapy tools provided, you can open potentially groundbreaking new dialogues with your clients. Author Judith Aron Rubin draws on more than forty years experience as an art therapist to help you maximize the value of art as a therapeutic tool, in both the mental health disciplines, such as psychology and social work, and related specialties. An accompanying DVD contains models for practitioners, showing art therapy being used in actual clinical practice. The DVD clearly models: * Initiating the art-making process * Using art in assessment * Using mental imagery, with or without art * Implementing other art forms–such as drama and music–in therapy * Using art with a variety of client types, including children, families, and groups * Assigning art as «homework» Whether or not you have used art therapy with your clients or are thinking about integrating art therapy in your practice, making the most of art in the clinical setting begins with Artful Therapy.
Neuropsychological Rehabilitation
Around 10 million people in the UK suffer from a neurological disorder, one million of whom are disabled by their condition. Neurological disorders that can affect cognitive functioning include stroke, head injury, multiple sclerosis and dementia. Historically the emphasis within neurology has been on diagnosis. Now neurologists also have to train in neuro-rehabilitation in order to help patients to cope with their condition, and they increasingly work within multi-disciplinary teams. The bulk of the book is formed of sessions plans for the six sessions over which the group may be run. The session plans includes a ‘script’ for the facilitator, slides and handouts. The introductory chapter will review the literature supporting the implementation of such groups, and the final chapter will go through some of the frequently asked questions.