Группа авторов
Список книг автора Группа авторовChiral Separation Techniques
Thoroughly revised, with either entirely new or completely updated contents, this is a practical manual for the small and large-scale preparation of enantiomerically pure products. The result is a vital resource for meeting the highest purity standards in the manufacture of chiral pharmaceuticals, food additives and related compounds. All the approaches covered here are highly relevant to modern manufacturing and quality control schemes in the pharmaceutical and biotech industries, addressing the increasingly important issue of drug safety in view of tougher regulatory standards worldwide.
Electrophoresis in Practice
This laboratory guide for successful electrophoretic separations is divided into two parts to provide readers with a thorough presentation of the fundamentals followed by a detailed description of the most common methods currently in use. This fourth edition retains the successful concept of its predecessors, yet features a brand-new layout, and is further enhanced by a section on difference gel electrophoresis, while the chapter on proteome analysis is practically all new and considerably extended, plus there are now around 10 % new literature references.
Practical Cell Analysis
As analytical chemistry and biology move closer together, biologists are performing increasingly sophisticated analytical techniques on cells. Chemists are also turning to cells as a relevant and important sample to study newly developed methods. Practical Cell Analysis provides techniques, hints, and time-saving tips explaining what may be “common knowledge” to one field but are often hidden or unknown to another. Within this practical guide: The procedures and protocols for cell separation, handling cells on a microscope and for using cells in microfluidic devices are presented. Elements of cell culture are taken and combined with the practical advice necessary to maintain a cell lab and to handle cells properly during an analysis The main chapters deal with the fundamentals and applied aspects of each technique, with one complete chapter focusing on statistical considerations of analyzing cells Many diagram-based protocols for some of the more common cell processes are included Chapter summaries and extensive tables are included so that key information can be looked up easily in the lab setting Much like a good manual or cookbook this book is a useful, practical guide and a handy reference for all students, researchers and practitioners involved in cellular analysis.
Electron Paramagnetic Resonance
Easy-to-follow guide helps you take full advantage of EPR spectroscopy's capabilities Electron Paramagnetic Resonance: A Practitioner's Toolkit serves as a practical guide that enables you to navigate through and make sense of the complex maze of electron paramagnetic resonance (EPR) spectroscopy fundamentals, techniques, and applications. The first half of this book is dedicated to explaining the core principles of EPR spectroscopy, using clear, easy-to-follow explanations and examples while avoiding complex physics and mathematics. The second half of the book focuses on applications, including problem-solving strategies for such fields as biology, medicine, material science, chemistry, physics, and radiation effects on matter. Carefully edited by two experienced EPR scientists, this book features a team of eighteen expert authors. Their contributions are based not only on a thorough examination and analysis of the primary literature, but also on their own firsthand experience in research and applications. As a result, the book is filled with practical advice, tips, and cautions addressing such issues as: Choosing the right experiment Selecting experimental parameters and sample size Avoiding setbacks and pitfalls Simulating the spectra With its straightforward explanations and clear examples, this book is just what researchers need to take full advantage of EPR spectroscopy's tremendous capabilities. It is particularly recommended for those interested in applications to chemistry, biology, medicine, and material science.
Validating Chromatographic Methods
All the information and tools needed to set up a successful method validation system Validating Chromatographic Methods brings order and Current Good Manufacturing Practices to the often chaotic process of chromatographic method validation. It provides readers with both the practical information and the tools necessary to successfully set up a new validation system or upgrade a current system to fully comply with government safety and quality regulations. The net results are validated and transferable analytical methods that will serve for extended periods of time with minimal or no complications. This guide focuses on high-performance liquid chromatographic methods validation; however, the concepts are generally applicable to the validation of other analytical techniques as well. Following an overview of analytical method validation and a discussion of its various components, the author dedicates a complete chapter to each step of validation: Method evaluation and further method development Final method development and trial method validation Formal method validation and report generation Formal data review and report issuance Templates and examples for Methods Validation Standard Operating Procedures, Standard Test Methods, Methods Validation Protocols, and Methods Validation Reports are all provided. Moreover, the guide features detailed flowcharts and checklists that lead readers through every stage of method validation to ensure success. All of the templates are also included on a CD-ROM, enabling readers to easily work with and customize them. For scientists and technicians new to method validation, this guide provides all the information and tools needed to develop a top-quality system. For those experienced with method validation, the guide helps to upgrade and improve existing systems. Note: CD-ROM/DVD and other supplementary materials are not included as part of eBook file.
Advances in Chemical Physics
This series provides the chemical physics field with a forum for critical, authoritative evaluations of advances in every area of the discipline. This stand-alone special topics volume reports recent advances in electron-transfer research with significant, up-to-date chapters by internationally recognized researchers.
Hydrothermal Properties of Materials
Hydrothermal Properties of Materials: Experimental Data on Aqueous Phase Equilibria and Solution Properties at Elevated Temperatures and Pressures is designed for any scientists and engineer who deals with hydrothermal investigations and technologies. The book is organized into eight chapters, each dealing with a key physical property of behavior of solutions, so that a reader can obtain information on: hydrothermal experimental methods; available experimental data and the main features of properties behavior in a wide range of temperatures and pressures; and possible ways of experimental data processing for obtaining the derivative properties.
Essentials of Computational Chemistry
Essentials of Computational Chemistry provides a balanced introduction to this dynamic subject. Suitable for both experimentalists and theorists, a wide range of samples and applications are included drawn from all key areas. The book carefully leads the reader thorough the necessary equations providing information explanations and reasoning where necessary and firmly placing each equation in context.
Developing Chemical Information Systems
Develop and manage chemical information systems This text provides a comprehensive overview of analyzing chemical problems using computer-aided methods for both newcomers and advanced computer scientists and chemists. In addition to practical how-to information and step-by-step descriptions, this resource includes case studies from Merck & Co., Inc., to further aid your understanding. This guide covers a wide range of cheminformatics topics, including: * Software development principles * Object-oriented approach * Building and buying * Agile and Iterative Development Process * UML Modeling * Deployment and Software Architecture * Presentation, Business, and Data Persistence Layer * Producing an entity dictionary * Chemistry Intelligence API * Plug and play–integrating with third-party tools Written by a former lead architect on the design of said systems at Merck & Co., Inc., this text not only lays out information, but also shares the author's experiences and advice on cheminformatics.
Introduction to Computational Chemistry
Introduction to Computational Chemistry Second Edition provides a comprehensive account of the fundamental principles underlying different methods, ranging from classical to the sophisticated. Although comprehensive in its coverage, this textbook focuses on calculating molecular structures and (relative) energies and less on molecular properties or dynamical aspects. No prior knowledge of concepts specific to computational chemistry are assumed, but the reader will need some understanding of introductory quantum mechanics, linear algebra, and vector, differential and integral calculus.