In recent years there has been a resurgence of interest in the work of Emmanuel Levinas, widely recognized as one of the most important yet difficult philosophers of the 20th century. In this much-needed introduction, Davis unpacks the concepts at the centre of Levinas's thought – alterity, the Other, the Face, infinity – concepts which have previously presented readers with major problems of interpretation. Davis traces the development of Levinas's thought over six decades, describing the context in which he worked, and the impact of his writings. He argues that Levinas's work remains tied to the ontological tradition with which he wants to break, and demonstrates how his later writing tries to overcome this dependency by its increasingly disruptive, sometimes opaque, textual practice. He discusses Levinas's theological writings and his relationship to Judaism, as well as the reception of his work by contemporary thinkers, arguing that the influence of his work has led to a growing interest in ethical issues among poststructuralist and postmodernist thinkers in recent years. Comprehensive and clearly written, this book will be essential reading for students and researchers in continental philosophy, French studies, literary theory and theology.
Jerry Fodor is one of the most important philosophers of mind in recent decades. He has done much to set the agenda in this field and has had a significant influence on the development of cognitive science. Fodor's project is that of constructing a physicalist vindication of folk psychology and so paving the way for the development of a scientifically respectable intentional psychology. The centrepiece of his engagement in this project is a theory of the cognitive mind, namely, the computational theory of mind, which postulates the existence of a language of thought. Fodor: Language, Mind and Philosophy is a comprehensive study of Fodor's writings. Individual chapters are devoted to each of the major issues raised by his work and contain extensive discussion of his relationships to key developments in cognitive science and to the views of such philosophical luminaries as Dennett, Davidson and Searle. This accessible book will appeal to advanced level undergraduate students of philosophy and related disciplines. It will also be of great interest to professional philosophers and cognitive scientists.
Statistics show that out of five thousand compounds with initial promise, five will go into human clinical trials, and only one will become an approved drug. This tiny fraction illustrates the huge complexities involved in bringing a drug to market, a process that brings together scientific research, medical ethics, business, and various regulatory agencies. Drugs-From Discovery to Approval presents a clear, step-by-step overview of the entire process. Using simple language, this comprehensive guide introduces basic concepts, then moves on to discuss disease target selection and the discovery processes for both small and large molecule drugs. Subsequent chapters explain preclinical studies, clinical trials, regulatory issues, good manufacturing practices (GMPs), and perspectives on the future. Coverage also includes: * A helpful listing of current FDA and European guidelines * A special section on regulatory authorities and processes in Japan and China * Rich illustrations throughout, including more than ninety figures and tables * Useful appendices on the history of drug discovery and development * Representative examples of drug mechanisms in action Written for professionals in the pharmaceutical industry, and readily accessible for students of pharmacy or medicine and others interested in drug discovery, Drugs-From Discovery to Approval represents a practical and approachable reference on this important process.
Describes the latest advances in psychopharmacology – one of the most rapidly developing fields in modern science. This latest edition has been updated to cover new developments in drug therapy and research including newly introduced antipsychotics, antidepressants and antidementia drugs. Sections on the treatment of depression and dementia have been revised to include new developments in treatment strategies. It will be welcomed for its essentially clinical and psychological approach to modern pharmaceuticals, their therapeutic uses and limitations, adverse reactions and future directions for research.
The latest edition of this highly acclaimed textbook, provides a comprehensive and up-to-date overview of the science and medical applications of biopharmaceutical products. Biopharmaceuticals refers to pharmaceutical substances derived from biological sources, and increasingly, it is synonymous with 'newer' pharmaceutical substances derived from genetic engineering or hybridoma technology. This superbly written review of the important areas of investigation in the field, covers drug production, plus the biochemical and molecular mechanisms of action together with the biotechnology of major biopharmaceutical types on the market or currently under development. There is also additional material reflecting both the technical advances in the area and detailed information on key topics such as the influence of genomics on drug discovery.
The fourth edition of Pharmacoepidemiology is an outstanding and fully comprehensive textbook, which will be an essential resource for all interested in the field—in academia, in regulatory agencies, in industry and in the law. Brian Strom’s classic textbook continues both to reflect the increased maturation of pharmacoepedemiology and to help shape it’s direction. Reviews of previous editions of his celebrated textbook include: «The book is essential reading for anyone interested in pharmacoepidemiology.» INTERNATIONAL JOURNAL OF EPIDEMIOLOGY “…an excellent textbook and a comprehensive reference which belongs in the library of every pharmaceutical manufacturer and regulator." EUROPEAN JOURNAL OF PUBLIC HEALTH
This important and extremely interesting book is a serious scientific and authoritative overview of the implications of drinking beer as part of the human diet. Coverage includes a history of beer in the diet, an overview of beer production and beer compositional analysis, the impact of raw materials, the desirable and undesirable components in beer and the contribution of beer to health, and social issues. Written by Professor Charlie Bamforth, well known for a lifetime's work in the brewing world, Beer: Health and Nutrition should find a place on the shelves of all those involved in providing dietary advice.
Our perceptions of dementia and what dementia care should constitute have changed dramatically over the past 20 years. Research has uncovered a mass of information concerning all aspects of dementia. This wealth of information should be reflected in a dramatic change, indeed a metamorphosis, in the way people with dementia are cared for. No such change has occurred. Dementia – Metamorphosis in Care will address the need for change and provide practitioners with a means of understanding why adhering to the old model – the medical approach – can be damaging in current care settings. Practitioners are advised on what is needed from them in order that they can positively influence the lives of those living with dementia. The importance of the role of professional carer and the responsibility they carry regarding whether or not care improves, is underlined throughout the book.
There are unique challenges in the formulation, manufacture, analytical chemistry, and regulatory requirements of low-dose drugs. This book provides an overview of this specialized field and combines formulation, analytical, and regulatory aspects of low-dose development into a single reference book. It describes analytical methodologies like dissolution testing, solid state NMR, Raman microscopy, and LC-MS and presents manufacturing techniques such as granulation, compaction, and compression. Complete with case studies and a discussion of regulatory requirements, this is a core reference for pharmaceutical scientists, regulators, and graduate students.
With accompanying software! Clinicians manage a lot of data – on assorted bits of paper and in their heads. This book is about better ways to manage and understand large amounts of clinical data. Following on from his ground breaking book, Evaluating the Processes of Neonatal Intensive Care, Joseph Schulman has produced this eminently readable guide to patient data analysis. He demystifies the technical methodology to make this crucial aspect of good clinical practice understandable and usable for all health care workers. Computer technology has been relatively slow to transform the daily work of health care, the way it has transformed other professions that work with large amounts of data. Each day, we do our work as we did it the day before, even though current technology offers much better ways. Here are much better ways to document and learn from the daily work of clinical care. Here are the principles of data management and analysis and detailed examples of how to implement them using computer technology. To show you that the knowledge is scalable and useful, and to get you off to a running start, the book includes a complete point of care database software application tailored to the neonatal intensive care unit (NICU). With examples from the NICU and the pediatric ward, this book is aimed specifically at the neonatal and pediatric teams. The accompanying software can be downloaded on to your system or PDA, so that continual record assessment becomes second nature – a skill that will immeasurably improve practice and outcomes for all your patients.