Группа авторов
Список книг автора Группа авторовRange and Richness of Vascular Land Plants
Published by the American Geophysical Union as part of the Special Publications Series. This is a research monograph and not a textbook. Here I demonstrate analytically how the observed, opposing, latitudinal gradients in the average range and richness of local vascular land plant species are (outside the moist-tropical zone, at least) driven primarily by the local temporal and spatial variability of shortwave radiative flux at the canopy top. (The term «richness» as used here means the local number of different vascular land plant species unlimited by the size of the area sampled.) The hypotheses are simplistic but are nevertheless convincingly accurate in extratropical latitudes when tested against observations over the continental land surfaces of the Northern Hemisphere, the only areas tested here.
An Introduction to Molecular Medicine and Gene Therapy
Gene therapy, or the use of genetic manipulation for disease treatment, is derived from advances in genetics, molecular biology, clinical medicine, and human genomics. Molecular medicine, the application of molecular biological techniques to disease treatment and diagnosis, is derived from the development of human organ transplantation, pharmacotherapy, and elucidation of the human genome. An Introduction to Molecular Medicine and Gene Therapy provides a basis for interpreting new clinical and basic research findings in the areas of cloning, gene transfer, and targeting; the applications of genetic medicine to clinical conditions; ethics and governmental regulations; and the burgeoning fields of genomics, biotechnology, and bioinformatics. By dividing the material into three sections – an introduction to basic science, a review of clinical applications, and a discussion of the evolving issues related to gene therapy and molecular medicine-this comprehensive manual describes the basic approaches to the broad range of actual and potential genetic-based therapies. In addition, An Introduction to Molecular Medicine and Gene Therapy: Covers new frontiers in gene therapy, animal models, vectors, gene targeting, and ethical/legal considerations Provides organ-based reviews of current studies in gene therapy for monogenetic, multifactoral or polygenic disorders, and infectious diseases Includes bold-faced terms, key concepts, summaries, and lists of helpful references by subject in each chapter Contains appendices on commercial implications and a review of the history of gene therapy This textbook offers a clear, concise writing style, drawing upon the expertise of the authors, all renowned researchers in their respective specialties of molecular medicine. Researchers in genetics and molecular medicine will all find An Introduction to Molecular Medicine and Gene Therapy to be an essential guide to the rapidly evolving field of gene therapy and its applications in molecular medicine.
Molecular and Genetic Analysis of Human Traits
Molecular and Genetic Analysis of Human Traits will address the science student human genetics market. Although incorporating two basic themes: how do we establish that a trait is hereditary, and how is the human genome organized, it will also address relevant clinical examples and key related ethical issues. New attractive features have been added, including a chapter project, and end of chapter exercises which rely on real data. Each chapter includes end of chapter exercises, and references. In-text examples and internet references are cited. Most figures will be 2 color, with some 4 color inserts.
Wave and Scattering Methods for Numerical Simulation
Scattering-based numerical methods are increasingly applied to the numerical simulation of distributed time-dependent physical systems. These methods, which possess excellent stability and stability verification properties, have appeared in various guises as the transmission line matrix (TLM) method, multidimensional wave digital (MDWD) filtering and digital waveguide (DWN) methods. This text provides a unified framework for all of these techniques and addresses the question of how they are related to more standard numerical simulation techniques. Covering circuit/scattering models in electromagnetics, transmission line modelling, elastic dynamics, as well as time-varying and nonlinear systems, this book highlights the general applicability of this technique across a variety of disciplines, as well as the inter-relationships between simulation techniques and digital filter design. provides a comprehensive overview of scattering-based numerical integration methods. reviews the basics of classical electrical network theory, wave digital filters, and digital waveguide networks. discusses applications for time-varying and nonlinear systems. includes an extensive bibliography containing over 250 references. Mixing theory and application with numerical simulation results, this book will be suitable for both experts and readers with a limited background in signal processing and numerical techniques.
Biology in Space and Life on Earth
This concise yet comprehensive treatment of the effects of spaceflight on biological systems includes issues at the forefront of life sciences research, such as gravitational biology, immune system response, bone cell formation and the effects of radiation on biosystems. Edited by a leading specialist at the European Space Agency (ESA) with contributions by internationally renowned experts, the chapters are based on the latest space laboratory experiments, including those on SPACELAB, ISS, parabolic flights and unmanned research satellites. An indispensable source for biologists, medical researchers and astronautics experts alike. The results of Space flight experiments, ground controls and flight simulations pave the way for a better understanding of gravity reactions in various organisms down to molecular mechanisms. This publication marks also the beginning of a new Space flight era with the construction and exploitation of the International Space Station (ISS) which provides a platform for an in-depth continuation of experiments under weightlessness in Low Earth Orbit and beyond.
Introduction to Contamination Control and Cleanroom Technology
Contamination control is being used by more and more industries where the highest level of cleanliness and hygiene is of vital importance. This book covers the basic principles of contamination control and cleanroom technology from a holistic point of view. It deals with cleanliness and hygiene and their effects on the outcome of a process, reflecting the latest results from both scientific and practical points of view. The following topics are covered: contaminants and how they are measured cleanrooms and clean zones cleaning and decontamination cleanroom clothing the impact of people on cleanliness. Intended as an introduction to the area of contamination control, the text is also an excellent source of knowledge for people with both theoretical and practical experience. The Swedish version has been used for a long time within the Nordic countries as a basic training textbook within the pharmaceutical, microelectronics, food and beverage, optics and many other industries.
Liquid Ring Vacuum Pumps, Compressors and Systems
Based on the very successful German editions, this English version has been thoroughly updated and revised to reflect the developments of the last years and the latest innovations in the field. Throughout, the author makes excellent use of real-life examples and highly praised didactics to disseminate his expert knowledge needed by vacuum technology users and engineers in their daily work at industrial plants, as consultants or in design offices. He covers in detail the most modern liquid ring pumps, with chapters dedicated to maintenance, explosion prevention and general procedures for safety at work with this technology. The whole is backed by a large repository of frequently needed technical data, unit conversions, formulae and current industrial, technical and legal norms without drawing on unnecessary complex or theoretical mathematics. The result is the ideal hands-on introduction to vacuum technology, ranging from fundamentals to in-depth expert knowledge on liquid-ring vacuum pumps.
The Investigation of Organic Reactions and Their Mechanisms
A range of alternative mechanisms can usually be postulated for most organic chemical reactions, and identification of the most likely requires detailed investigation. Investigation of Organic Reactions and their Mechanisms will serve as a guide for the trained chemist who needs to characterise an organic chemical reaction and investigate its mechanism, but who is not an expert in physical organic chemistry. Such an investigation will lead to an understanding of which bonds are broken, which are made, and the order in which these processes happen. This information and knowledge of the associated kinetic and thermodynamic parameters are central to the development of safe, efficient, and profitable industrial chemical processes, and to extending the synthetic utility of new chemical reactions in chemical and pharmaceutical manufacturing, and academic environments. Written as a coherent account of the principal methods currently used in mechanistic investigations, at a level accessible to academic researchers and graduate chemists in industry, the book is highly practical in approach. The contributing authors, an international group of expert practitioners of the techniques covered, illustrate their contributions by examples from their own research and from the relevant wider chemical literature. The book covers basic aspects such as product analysis, kinetics, catalysis, and investigation of reactive intermediates. It also includes material on significant recent developments, e.g. computational chemistry, calorimetry, and electrochemistry, in addition to topics of high current industrial relevance, e.g. reactions in multiphase systems, and synthetically useful reactions involving free radicals and catalysis by organometallic compounds.
Peptide and Protein Design for Biopharmaceutical Applications
Peptides serve as effective drugs in the clinic today. However the inherent drawbacks of peptide structures can limit their efficacy as drugs. To overcome this researchers are developing new methods to create ‘tailor-made’ peptides and proteins with improved pharmacological properties. Design of Peptides and Proteins provides an overview of the experimental and computational methods for peptide and protein design, with an emphasis on specific applications for therapeutics and biomedical research. Topics covered include: Computer modeling of peptides and proteins Peptidomimetics Design and synthesis of cyclic peptides Carbohydrates in peptide and protein design De novo design of peptides and proteins Medical development applications An extended case study – the design of insulin variants Design of Peptides and Proteins presents the state-of-the-art of this exciting approach for therapeutics, with contributions from international experts. It is an essential resource for academic and industrial scientists in the fields of peptide and protein drug design, biomedicine, biochemistry, biophysics, molecular modelling, synthetic organic chemistry and medicinal/pharmaceutical chemistry.
Hazardous Waste Operations and Emergency Response Manual
Field technicians and emergency response personnel are often faced with the dangers of flammable, combustible, and chemically unstable materials. Although there are numerous procedures set forth by regulatory agencies like the Occupational Safety and Health Administration (OSHA), the Environmental Protection Agency (EPA), and the National Institute for Occupational Safety and Health (NIOSH) for effectively and safely dealing with such environmental hazards, up until now there has been no single resource for training in this area. Based on the author's twenty-plus years of field experience, Hazardous Waste Operations and Emergency Response Manual is a comprehensive text that covers the complete curriculum requirements set forth by OSHA and HazWOPER. Highly accessible and broad in focus, the book is equally useful as a technical resource for training, a hands-on reference for field operations, and a textbook for environmental courses in a variety of areas. Coverage includes:Methods recommended by professional societies and regulatory agencies including the National Fire Protection Association, OSHA, EPA, and NIOSHPractical examples and assignments in each chapter to supplement the text and enhance usefulness to students.