The rapid pace of evolution in domino, or cascade-based transformations has revolutionized the practice of chemical synthesis for the creation of natural products, designed molecules, and pharmaceuticals. «Science of Synthesis: Applications of Domino Transformations in Organic Synthesis» explores the topic thoroughly and systematically, serving as the basis for practical applications and future research. The 2-volume set presents the cutting-edge in terms of design, strategy, and experimental procedures, leading to multiple events being accomplished within a single reaction vessel. The content is organized by the core type of reaction used to initiate the event, be it a pericyclic reaction, a metal-mediated transformation, radical chemistry, or an acid-induced cascade among many others. Volume 1 covers polyene/cation-pi cyclizations, metathesis, radical, and metal-mediated reactions, and non-radical skeletal rearrangements.
The reference work «Science of Synthesis: Catalytic Transformations via C-H Activation» covers the state of the art in C-H activation chemistry. Experts in the field present the best synthetic methods including typical or general experimental procedures. As such, this two volume set can serve as both a basis for the practical application of the techniques discussed, and as an educational resource to lay the foundations for future research. Volume 2 concerns the formation of C-C bonds by C-H activation of non-(het)arene substrates as well as C-H activation using special reagents or techniques. The formation of C-heteroatom bonds by predominantly arene C-H activation is also reviewed. For C-C bond formation, the material is subdivided into allylic, alkyl, and double C-H activation techniques, coupling using carbenes or radicals, and carbonylation or carboxylation processes.
The reference work «Science of Synthesis: Catalytic Transformations via C-H Activation» covers the state of the art in C-H activation chemistry. Experts in the field present the best synthetic methods including typical or general experimental procedures. As such, this two volume set can serve as both a basis for the practical application of the techniques discussed, and as an educational resource to lay the foundations for future research. Volume 1 concerns the formation of C-C bonds by both arene and hetarene C-H activation. For the arenes the material is subdivided into arylation (using palladium(0), palladium(II)/palladium(IV), palladium(II), and ruthenium(II) catalysts), vinylation (using various palladium and ruthenium(III) catalysts), and alkylation (using various metal catalysts in combination with either functionalized alkanes or alkenes). For the hetarenes, the related coupling strategies are covered as a single topic using a variety of metal catalysts and coupling partners.
The management of traumatic and reconstructive problems of the hand has become an ever more complex field. Advances in basic science and technology together with a growth in clinical expertise have resulted in recent dramatic changes in many of the implants, instruments, and techniques used in modern hand surgery.Manual of Fracture Management: Hand by Jesse Jupiter, Fiesky NuÃ±ez, and Renato Fricker is a principally case-based publication designed to instruct and introduce new technologies and methods to both new and experienced hand surgeons. The book's key features include: Detailed case descriptions and recommended treatment options for a wide variety of fracture and injury types, from spiral to transverse, and multifragmentary to malunion, involving the proximal middle and distal phalanges of the fingers and thumb, the metacarpals, and the jointsMore than 2250 high-quality illustrations and clinical imagesAccess to an online video library of dozens of hand surgery approaches and clinical demonstrations.Using the principles and techniques developed by leading surgical specialists from the renowned AO Foundation, AOTrauma is proud to bring you this exciting update, which will be an ideal resource for trauma and orthopedic surgery professionals, residents in training, and medical studentsaround the world. Hear the authors discuss Manual of Fracture Management – Hand .
This sixth volume in the AOSpine Masters Series provides expert guidance on making an accurate diagnosis and classification of injuries to the thoracolumbar area of the spine. Chapters include: Radiographic Assessment of Thoracolumbar Fractures, Posterior and Anterior MIS in TL Fractures, and Thoracolumbar Fracture Fixation in the Osteoporotic Patient.Key Features:Each chapter provides historic literature as well as a synthesized analysis of current literature and proposes an evidence-based treatment planEditors are international authorities on thoracolumbar spine trauma Expert tips and pearls included in every chapterThe AOSpine Masters Series, a copublication of Thieme and AOSpine, a Clinical Division of the AO Foundation, addresses current clinical issues whereby international masters of spine share their expertise and recommendations on a particular topic. The goal of the series is to contribute to an evolving, dynamic model of an evidence-based medicine approach to spine care.All spine surgeons and orthopaedic surgeons, along with residents and fellows in these areas, will find this book to be an excellent reference that they will consult often in their treatment of patients with thoracolumbar spine injuries.
City of Weird conjures what we fear: death, darkness, ghosts. Hungry sea monsters and alien slime molds. Blood drinkers and game show hosts. Set in Portland, Oregon, these thirty stories blend imagination, literary writing, and pop culture into a cohesive weirdness that honors the city’s personality, its bookstores and bridges and solo volcano, as well as the tradition of sci-fi pulp magazines. Including such authors as Rene Denfeld, Justin Hocking, Leni Zumas, and Kevin Sampsell, editor Gigi Little has curated a collection that is quirky, chilling, often profound—and always perfectly weird.
Black and Brown Planets embarks on a timely exploration of the American obsession with color in its look at the sometimes contrary intersections of politics and race in science fiction. The contributors, including De Witt D. Kilgore, Edward James, Lisa Yaszek, and Marleen S. Barr, among others, explore science fiction worlds of possibility (literature, television, and film), lifting blacks, Latin Americans, and indigenous peoples out from the background of this historically white genre.This collection considers the role of race and ethnicity in our visions of the future. The first section emphasizes the political elements of black identity portrayed in science fiction from black America to the vast reaches of interstellar space framed by racial history. In the next section, analysis of indigenous science fiction addresses the effects of colonization, helps discard the emotional and psychological baggage carried from its impact, and recovers ancestral traditions in order to adapt in a post-Native-apocalyptic world. Likewise, this section explores the affinity between science fiction and subjectivity in Latin American cultures from the role of science and industrialization to the effects of being in and moving between two cultures. By infusing more color in this otherwise monochrome genre, Black and Brown Planets imagines alternate racial galaxies with viable political futures in which people of color determine human destiny.
Biomechanics of Spine Stabilization, Third Edition, is a comprehensive and highly readable reference that helps spine specialists understand the clinically important biomechanical principles underpinning spinal surgery and instrumentation so that the best clinical decisions can be made for patients. This new edition includes coverage of the latest spine technology that has evolved over the past decade, such as motion preservation technologies and minimally invasive spine surgery.Features: Single-authored text with the consistent, authoritative voice of world-renowned expert Dr. BenzelMore than 350 new figures and original line drawings help clarify information in the textExtensive glossary of basic terminology on biomechanics for quick, easy referenceMore than 400 review questions at the back of the book for help with exam preparationThis book is an excellent clinical reference for spine surgeons, residents, and fellows in the fields of orthopedic surgery and neurosurgery, neuroradiologists, and engineers working for spine device companies. Thieme eNeurosurgery is the worlds most comprehensive neurosurgical resource online. For a free trial, go to: thieme.com/eneurotrial
Asian citrus psyllid (ACP), Diaphorina citri, is an insect pest which transmits a bacterium, Candidatus Liberibacter asiaticus (CLas), primarily through feeding in newly emergent foliage of citrus trees. This pathogen causes a disease known as Huanglongbing (HLB), or citrus greening, which has become the most debilitating and intractable disease in citrus crops.
This book, written by a team of experts on the Asian citrus psyllid, gathers together everything currently known about the biology and ecology of this important pest species, examines the transmission and acquisition processes of the pathogen, and looks at current management practices and their effectiveness. The potential for new, innovative management techniques are also described, along with the economic implications of managing this rapidly establishing disease.
Covers all aspects of Asian citrus psyllid biology and ecology for the first time in one place. Examines new, innovative management practices and assesses their effectiveness. Discusses the vector-pathogen relationship in detail. Explains the economics of controlling this devastating pest.
This title is essential reading for all researchers involved in the management and control of Asian citrus psyllid, extension agents, and pest management consultants. It will also be of great use to graduate students in applied entomology and related disciplines.
From bioinformatics to nanotechnology, advances in basic research ultimately drive advances in clinical care. This book provides a comprehensive summary of all current research methodologies for translational and pre-clinical studies in biomechanics and orthopedic trauma surgery. With this roadmap at hand, specialists and trainees will have the tools to conduct high-quality experimental research in any area of musculoskeletal science, with a solid understanding of how the findings can be applied in patient care. Special Features: Utilizes the principles and methodology of modern, evidence-based medicine in pre-clinical musculoskeletal research Offers a comprehensive analysis of in vivo models for studying different components of the musculoskeletal system Demonstrates how principles of structural, functional, and numerical biomechanics can be utilized in well-defined experimental research studies spanning topics from fracture fixation to gait analysis to bone remodeling Covers the role of new macroscopic CT and ultrasound imaging techniques for assessing bone and cartilage function Explores cutting-edge developments in cell culture research, molecular testing, and tissue engineering Provides practical advice, a glossary of key terminology, and hundreds of illustrations to familiarize clinicians with every aspect of designing and interpreting an effective research study With 54 state-of-the-art chapters by orthopedic surgeons, musculoskeletal physicians, biologists, engineers, physicists, and mathematicians, Experimental Research Methods in Orthopedics and Trauma is the authoritative reference on the topic. It is essential for clinicians, basic researchers, and orthopedic surgical trainees who need to understand experimental research methodology, apply its findings, and participate fully in research activities.