Genome Editing in Drug Discovery. Группа авторов

(1996). Correction of the mutation responsible for sickle cell anemia by an RNA‐DNA oligonucleotide. Science 273: 1386–1389.

      17 Cristea, S., Freyvert, Y., Santiago, Y. et al. (2013). in vivo cleavage of transgene donors promotes nuclease‐mediated targeted integration. Biotechnol. Bioeng. 110: 871–880.

      18 Ding, Q., Lee, Y.K., Schaefer, E.A. et al. (2013). A TALEN genome‐editing system for generating human stem cell‐based disease models. Cell Stem Cell 12: 238–251.

      19 Doyon, Y., Mccammon, J.M., Miller, J.C. et al. (2008). Heritable targeted gene disruption in zebrafish using designed zinc‐finger nucleases. Nat. Biotechnol. 26: 702–708.

      20 Garneau, J.E., Dupuis, M.E., Villion, M. et al. (2010). The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA. Nature 468: 67–71.

      21 Gaudelli, N.M., Komor, A.C., Rees, H.A. et al. (2017). Programmable base editing of A*T to G*C in genomic DNA without DNA cleavage. Nature 551: 464–471.

      22 Geurts, A.M., Cost, G.J., Freyvert, Y. et al. (2009). Knockout rats via embryo microinjection of zinc‐finger nucleases. Science 325: 433.

      23 Guilinger, J.P., Thompson, D.B., and Liu, D.R. (2014). Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification. Nat. Biotechnol. 32: 577–582.

      24 Hanna, R.E. and Doench, J.G. (2020). Design and analysis of CRISPR‐Cas experiments. Nat. Biotechnol. 38: 813–823.

      25 Hess, G.T., Fresard, L., Han, K. et al. (2016). Directed evolution using dCas9‐targeted somatic hypermutation in mammalian cells. Nat. Methods 13: 1036–1042.

      26 Hinnen, A., Hicks, J.B., and Fink, G.R. (1978). Transformation of yeast. Proc. Natl. Acad. Sci. U. S. A. 75: 1929–1933.

      27 Hirata, R., Chamberlain, J., Dong, R., and Russell, D.W. (2002). Targeted transgene insertion into human chromosomes by adeno‐associated virus vectors. Nat. Biotechnol. 20: 735–738.

      28 Ishino, Y., Shinagawa, H., Makino, K. et al. (1987). Nucleotide sequence of the iap gene, responsible for alkaline phosphatase isozyme conversion in escherichia coli, and identification of the gene product. J. Bacteriol. 169: 5429–5433.

      29 Jiang, W., Bikard, D., Cox, D. et al. (2013). RNA‐guided editing of bacterial genomes using CRISPR‐Cas systems. Nat. Biotechnol. 31: 233–239.

      30 Jiang, W., Zhao, X., Gabrieli, T. et al. (2015). Cas9‐assisted targeting of CHromosome segments CATCH enables one‐step targeted cloning of large gene clusters. Nat. Commun. 6: 8101.

      31 Kim, Y.G., Cha, J., and Chandrasegaran, S. (1996). Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain. Proc. Natl. Acad. Sci. U. S. A. 93: 1156–1160.

      32 Kim, H.J., Lee, H.J., Kim, H. et al. (2009). Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly. Genome Res. 19: 1279–1288.

      33 Klompe, S.E., Vo, P.L.H., Halpin‐Healy, T.S., and Sternberg, S.H. (2019). Transposon‐encoded CRISPR‐Cas systems direct RNA‐guided DNA integration. Nature 571: 219–225.

      34 Komor, A.C., Kim, Y.B., Packer, M.S. et al. (2016). Programmable editing of a target base in genomic DNA without double‐stranded DNA cleavage. Nature 533: 420–424.

      35 Li, S., Akrap, N., Cerboni, S. et al. (2021). Universal toxin‐based selection for precise genome engineering in human cells. Nat. Commun. 12: 497.

      36 Maeder, M.L., Thibodeau‐Beganny, S., Osiak, A. et al. (2008). Rapid “open‐source” engineering of customized zinc‐finger nucleases for highly efficient gene modification. Mol. Cell 31: 294–301.

      37 Maier, D.A., Brennan, A.L., Jiang, S. et al. (2013). Efficient clinical scale gene modification via zinc finger nuclease‐targeted disruption of the HIV co‐receptor CCR5. Hum. Gene Ther. 24: 245–258.

      38 Makarova, K.S., Grishin, N.V., Shabalina, S.A. et al. (2006). A putative RNA‐interference‐based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action. Biol. Direct 1: 7.

      39 Maresca, M., Erler, A., Fu, J. et al. (2010). Single‐stranded heteroduplex intermediates in lambda red homologous recombination. BMC Mol. Biol. 11: 54.

      40 Maresca, M., Lin, V.G., Guo, N., and Yang, Y. (2013). Obligate ligation‐gated recombination (ObLiGaRe): custom‐designed nuclease‐mediated targeted integration through nonhomologous end joining. Genome Res. 23: 539–546.

      41 Marraffini, L.A. and Sontheimer, E.J. (2008). CRISPR interference limits horizontal gene transfer in staphylococci by targeting DNA. Science 322: 1843–1845.

      42 Miller, J., Mclachlan, A.D., and Klug, A. (1985). Repetitive zinc‐binding domains in the protein transcription factor IIIA from Xenopus oocytes. EMBO J. 4: 1609–1614.

      43 Moscou, M.J. and Bogdanove, A.J. (2009). A simple cipher governs DNA recognition by TAL effectors. Science 326: 1501.

      44 Murphy, K.C. (1998). Use of bacteriophage lambda recombination functions to promote gene replacement in Escherichia coli. J. Bacteriol. 180: 2063–2071.

      45 Pavletich, N.P. and Pabo, C.O. (1991). Zinc finger‐DNA recognition: crystal structure of a Zif268‐DNA complex at 2.1 A. Science 252: 809–817.

      46 Perez, E.E., Wang, J., Miller, J.C. et al. (2008). Establishment of HIV‐1 resistance in CD4+ T cells by genome editing using zinc‐finger nucleases. Nat. Biotechnol. 26: 808–816.

      47 Porteus, M.H. and Baltimore, D. (2003). Chimeric nucleases stimulate gene targeting in human cells. Science 300: 763.

      48 Reyon, D., Tsai, S.Q., Khayter, C. et al. (2012). FLASH assembly of TALENs for high‐throughput genome editing. Nat. Biotechnol. 30: 460–465.

      49 Richardson, C.D., Ray, G.J., Dewitt, M.A. et al. (2016). Enhancing homology‐directed genome editing by catalytically active and inactive CRISPR‐Cas9 using asymmetric donor DNA. Nat. Biotechnol. 34: 339–344.

      50 Sakamoto, K.M., Kim, K.B., Kumagai, A. et al. (2001). Protacs: chimeric molecules that target proteins to the Skp1‐Cullin‐F box complex for ubiquitination and degradation. Proc. Natl. Acad. Sci. U. S. A. 98: 8554–8559.

      51 Sakuma, T., Nakade, S., Sakane, Y. et al. (2016). MMEJ‐assisted gene knock‐in using TALENs and CRISPR‐Cas9 with the PITCh systems. Nat. Protoc. 11: 118–133.

      52 Santiago, Y., Chan, E., Liu, P.Q. et al. (2008). Targeted gene knockout in mammalian cells by using engineered zinc‐finger nucleases. Proc. Natl. Acad. Sci. U. S. A. 105: 5809–5814.

      53 Sarov, M., Schneider, S., Pozniakovski, A. et al. (2006). A recombineering pipeline for functional genomics applied to Caenorhabditis elegans. Nat. Methods 3: 839–844.

      54 Scherer, S. and Davis, R.W. (1979). Replacement of chromosome segments with altered DNA sequences constructed in vitro. Proc. Natl. Acad. Sci. U. S. A. 76: 4951–4955.

      55 Shalem, O., Sanjana, N.E., Hartenian, E. et al. (2014). Genome‐scale CRISPR‐Cas9 knockout screening in human cells. Science 343: 84–87.

      56 Si, T., Chao, R., Min, Y. et al. (2017). Automated multiplex genome‐scale engineering in yeast. Nat. Commun. 8: 15187.

      57 Skarnes, W.C., Rosen, B., West, A.P. et al. (2011). A conditional knockout resource for the genome‐wide study of mouse gene function. Nature 474: 337–342.

      58 Smanski, M.J., Zhou, H., Claesen, J. et al. (2016). Synthetic biology to access and expand nature's chemical diversity. Nat. Rev. Microbiol. 14: 135–149.

      59 Strathern, J.N., Klar, A.J., Hicks, J.B. et al. (1982). Homothallic switching of yeast mating type cassettes is initiated by a double‐stranded cut in the MAT locus. Cell 31: 183–192.

      60 Strecker, J., Ladha, A., Makarova, K.S. et al. (2020). Response to Comment on “RNA‐guided DNA insertion with CRISPR‐associated transposases”. Science 368: eabb2920.

      61 Su, T., Liu, F., Gu, P. et al. (2016). A CRISPR‐Cas9