Pathology of Genetically Engineered and Other Mutant Mice. Группа авторов

Genetic Background Effects References

      12  7 Hematopoietic and Lymphoid Tissues Introduction Bone Marrow Lymphoid Tissues Acknowledgments References

      13  8 Mouse Hematolymphoid Neoplasms Introduction and Overview of the Classification of Leukemias and Lymphomas in the Mouse Nonlymphoid Hematopoietic Neoplasms in Mice Nonlymphoid Hematopoietic Sarcomas Lymphoid Neoplasms Final Considerations Acknowledgments References

      14  9 Immunodeficient and Humanized Mice Introduction Uses of Immunodeficient Mouse Models Common Lesions in Immunodeficient Mice References

      15  10 Skin, Hair, and Nails Introduction Normal Anatomy and Embryology of Mouse Skin, Hair, and Nails Practical Guidelines for the Biological Characterization of a New Mutation Categories of Disease of the Skin and Adnexa Skin Cancers Bullous and Acantholytic Skin Diseases: Pemphigus, Pemphigoid, and Epidermolysis Bullosa Structural and Growth Defects in Nails Summary Acknowledgments References

      16  11 Mammary Gland Introduction Anatomy, Histology, and Biology of Mouse Mammary Glands Mammary Gland Biology Pathology of the Mammary Gland Neoplastic Progression Mammary Tumor Invasion and Metastases Genetic Engineering of Mouse Mammary Gland Promoters Oncogenes and Tumor Suppressors Oncogene Addiction and Nononcogene Addiction (NOA) Metaplasia Host and Environmental Factors GEM Mammary Tumors Pathology Preparation of Mammary Gland Whole Mounts Preparation of Lung Whole Mounts Case Study: 129S6/SvEvTac‐Stat1^tm1Rds Mammary Biology and Tumorigenesis (Figures 11.2, 11.7, and 11.10) Summary Internet Resources References

      17  12 The Respiratory Tract Introduction The Upper Respiratory Tract The Lung Disease Models References

      18  13 The Gastrointestinal Tract Introduction Stomach The Small and Large Intestine References

      19  14 Cardiovascular System Mouse Anatomy, Histology, and Physiology Special Necropsy Organ Protocols Genetically Engineered Mice (GEMs) Models of Heart and Vessel Disease Acknowledgments References

      20  15 Liver and Pancreas Liver Exocrine Pancreas References

      21  16 Neuromuscular System