Прочая образовательная литература
Различные книги в жанре Прочая образовательная литератураDiscovering the Future of Molecular Sciences
The European Young Chemist Award has now been awarded four times (2006, 2008, 2010 and 2012). The authors of the previous books based on the competition have become some of the leading scientists in Europe. These books truly provide a glimpse into the future research landscape of European chemistry. Fifteen top contributions have been selected for this single volume covering areas of chemistry and materials science. The broad range of themes is presented in an approachable and readable manner equally appropriate for non-specialists on the topic. The overview of intriguing topics includes chemical synthesis and advanced methodologies as well as materials, nanoscience and nanotechnologies.
Biochemistry of Signal Transduction and Regulation
Originally based on a graduate course taught by the author, this true classic has once again been extensively updated to incorporate key new findings in biological signaling. With over half of the content re-written, plus 70 brand new and 50 revised figures, this is the most up-to-date textbook on signaling available anywhere. Thanks to its clear structure, hundreds of illustrative drawings, as well as chapter introductions and newly added study questions, this text excels as a companion for a course on biological signaling, and equally as an introductory reference to the field for students and researchers. Generations of students and junior researchers have relied on «the Krauss» to find their way through the bewildering complexity of biological signaling pathways.
Modern Methods in Stereoselective Aldol Reactions
The selective formation of bondings between molecules is one of the major challenges in organic chemistry, and the so-called aldol reaction is one of the most important for this purpose. These reactions are a highly useful tool for developing such novel substances as natural products and pharmaceuticals. Likes its highly successful and much appreciated predecessor, «Modern Aldol Reactions», this ready reference provides a systematic overview of methodologies for installing a required configuration during an aldol addition step, but shifts the focus so as to cover the latest developments. As such, it presents a set of brand new tools, including vinylogous Mukaiyama-aldol reactions and substrate-controlled aldol reactions, as well as asymmetric induction in aldol additions. Furthermore, new developments in existing stereoselective aldol additions are described, such as the deployment of supersilyl groups or organocatalyzed aldol additions. All of these methodologies are presented in the context of their deployment in the total synthesis of natural products.
Matrix Proteases in Health and Disease
Presenting a comprehensive overview of the multifaceted field of proteases in the extracellular matrix environment, this reference focuses on the recently elucidated functions of complex proteolytic systems in physiological and pathological tissue remodeling. The proteases treated include both serine proteases such as plasminogen activators and TTSPs, metalloproteases such as MMPs and ADAMS and cysteine protease cathepsins. The text specifically addresses the role of extracellular proteases in cancer cell invasion, stroke and infectious diseases, describing the basic biochemistry behind these disease states, as well as therapeutic strategies based on protease inhibition. With its trans-disciplinary scope, this reference bridges the gap between fundamental research and biomedical and pharmaceutical application, making this required reading for basic and applied scientists in the molecular life sciences.
Practical Finite Element Modeling in Earth Science using Matlab
Mathematical models have become a crucial way for the Earth scientist to understand and predict how our planet functions and evolves through time and space. The finite element method (FEM) is a remarkably flexible and powerful tool with enormous potential in the Earth Sciences. This pragmatic guide explores how a variety of different Earth science problems can be translated and solved with FEM, assuming only basic programming experience. This book begins with a general introduction to numerical modeling and includes multiple sample Matlab codes to illustrate how FEM is implemented in practice. Textboxes have been included to provide additional detail, such as specialized Matlab usage or advanced topics. Covering all the key aspects, this is essential reading for those looking to master the technique, as well as those simply seeking to increase their basic level of understanding and appreciation of FEM.
Flows and Chemical Reactions in Heterogeneous Mixtures
This book – a sequel of previous publications 'Flows and Chemical Reactions' and 'Chemical Reactions in Flows and Homogeneous Mixtures' – is devoted to flows with chemical reactions in heterogeneous environments. Heterogeneous media in this volume include interfaces and lines. They may be the site of radiation. Each type of flow is the subject of a chapter in this volume. We consider first, in Chapter 1, the question of the generation of environments biphasic individuals: dusty gas, mist, bubble flow. Chapter 2 is devoted to the study at the mesoscopic scale: particle-fluid exchange of momentum and heat with determination of the respective exchange coefficients. In Chapter 3, we establish simplified equations of macroscopic balance for mass, for the momentum and energy, in the case of particles of one size (monodisperse suspension). Radiative phenomena are presented in Chapter 5.
Mechanical Vibration and Shock Analysis, Sinusoidal Vibration
Everything engineers need to know about mechanical vibration and shock…in one authoritative reference work! This fully updated and revised 3rd edition addresses the entire field of mechanical vibration and shock as one of the most important types of load and stress applied to structures, machines and components in the real world. Examples include everything from the regular and predictable loads applied to turbines, motors or helicopters by the spinning of their constituent parts to the ability of buildings to withstand damage from wind loads or explosions, and the need for cars to maintain structural integrity in the event of a crash. There are detailed examinations of underlying theory, models developed for specific applications, performance of materials under test conditions and in real-world settings, and case studies and discussions of how the relationships between these affect design for actual products. Invaluable to engineers specializing in mechanical, aeronautical, civil, electrical and transportation engineering, this reference work, in five volumes is a crucial resource for the solution of shock and vibration problems. The relative and absolute response of a mechanical system with a single degree of freedom is considered for an arbitrary excitation, and its transfer function is defined in various forms. The characteristics of sinusoidal vibration are examined in the context both of the real world and of laboratory tests, and for both transient and steady state response of the one-degree-of-freedom system. Viscous damping and then non-linear damping are considered. The various types of swept sine perturbations and their properties are described and, for the one-degree-of-freedom system, the consequence of an inappropriate choice of sweep rate are considered. From the latter, rules governing the choice of suitable sweep rates are then developed.
Bioprocessing of Renewable Resources to Commodity Bioproducts
This book provides the vision of a successful biorefinery—the lignocelluloic biomass needs to be efficiently converted to its constituent monomers, comprising mainly of sugars such as glucose, xylose, mannose and arabinose. Accordingly, the first part of the book deals with aspects crucial for the pretreatment and hydrolysis of biomass to give sugars in high yield, as well as the general aspects of bioprocessing technologies which will enable the development of biorefineries through inputs of metabolic engineering, fermentation, downstream processing and formulation. The second part of the book gives the current status and future directions of the biological processes for production of ethanol (a biofuel as well as an important commodity raw material), solvents (butanol, isobutanol, butanediols, propanediols), organic acids (lactic acid, 3-hydroxy propionic acid, fumaric acid, succinic acid and adipic acid), and amino acid (glutamic acid). The commercial production of some of these commodity bioproducts in the near future will have a far reaching effect in realizing our goal of sustainable conversion of these renewable resources and realizing the concept of biorefinery. Suitable for researchers, practitioners, graduate students and consultants in biochemical/ bioprocess engineering, industrial microbiology, bioprocess technology, metabolic engineering, environmental science and energy, the book offers: Exemplifies the application of metabolic engineering approaches for development of microbial cell factories Provides a unique perspective to the industry about the scientific problems and their possible solutions in making a bioprocess work for commercial production of commodity bioproducts Discusses the processing of renewable resources, such as plant biomass, for mass production of commodity chemicals and liquid fuels to meet our ever- increasing demands Encourages sustainable green technologies for the utilization of renewable resources Offers timely solutions to help address the energy problem as non-renewable fossil oil will soon be unavailable
Ex-vivo and In-vivo Optical Molecular Pathology
The result of a unique collaboration between clinicians, chemists and physicists, this book provides an unparalleled overview of a new generation of diagnostic tools in clinical pathology. The introductory chapters cover the present status and limitations of currently used methods, followed by an outline of promising novel spectroscopy-based technologies either under development or recently available on the market. The input from both technologists developing these new methods as well as routine clinicians familiar with practical aspects and medical relevance guarantees that this practical work is a valuable asset for a wide audience, including technical personnel and decision makers in treatment centers, experts working in companies developing diagnostic devices, and clinicians specializing in advanced diagnostic methods. Since basic researchers are increasingly adopting novel diagnostic tools developed for human use as well, this will also be of interest for biomedical research institutions with large animal facilities.
Quality of Service in Optical Packet Switched Networks
This book is a comprehensive study on OPS networks, its architectures, and developed techniques for improving its quality of switching and managing quality of service. The book includes: Introduction to OPS networks, OOFDM networks, GMPLS-enabled optical networks, QoS in OPS networks Hybrid contention avoidance/resolution schemes in both long-haul and metro optical networks Hybrid optical switching schemes