Прочая образовательная литература
Различные книги в жанре Прочая образовательная литератураBioinformatics and Functional Genomics
The bestselling introduction to bioinformatics and genomics – now in its third edition Widely received in its previous editions, Bioinformatics and Functional Genomics offers the most broad-based introduction to this explosive new discipline. Now in a thoroughly updated and expanded third edition, it continues to be the go-to source for students and professionals involved in biomedical research. This book provides up-to-the-minute coverage of the fields of bioinformatics and genomics. Features new to this edition include: Extensive revisions and a slight reorder of chapters for a more effective organization A brand new chapter on next-generation sequencing An expanded companion website, also updated as and when new information becomes available Greater emphasis on a computational approach, with clear guidance of how software tools work and introductions to the use of command-line tools such as software for next-generation sequence analysis, the R programming language, and NCBI search utilities The book is complemented by lavish illustrations and more than 500 figures and tables – many newly-created for the third edition to enhance clarity and understanding. Each chapter includes learning objectives, a problem set, pitfalls section, boxes explaining key techniques and mathematics/statistics principles, a summary, recommended reading, and a list of freely available software. Readers may visit a related Web page for supplemental information such as PowerPoints and audiovisual files of lectures, and videocasts of how to perform many basic operations: www.wiley.com/go/pevsnerbioinformatics. Bioinformatics and Functional Genomics, Third Edition serves as an excellent single-source textbook for advanced undergraduate and beginning graduate-level courses in the biological sciences and computer sciences. It is also an indispensable resource for biologists in a broad variety of disciplines who use the tools of bioinformatics and genomics to study particular research problems; bioinformaticists and computer scientists who develop computer algorithms and databases; and medical researchers and clinicians who want to understand the genomic basis of viral, bacterial, parasitic, or other diseases.
Introduction to Nonlinear Oscillations
A systematic outline of the basic theory of oscillations, combining several tools in a single textbook. The author explains fundamental ideas and methods, while equally aiming to teach students the techniques of solving specific (practical) or more complex problems. Following an introduction to fundamental notions and concepts of modern nonlinear dynamics, the text goes on to set out the basics of stability theory, as well as bifurcation theory in one and two-dimensional cases. Foundations of asymptotic methods and the theory of relaxation oscillations are presented, with much attention paid to a method of mappings and its applications. With each chapter including exercises and solutions, including computer problems, this book can be used in courses on oscillation theory for physics and engineering students. It also serves as a good reference for students and scientists in computational neuroscience.
Mathematical Tools for Physicists
The new edition is significantly updated and expanded. This unique collection of review articles, ranging from fundamental concepts up to latest applications, contains individual contributions written by renowned experts in the relevant fields. Much attention is paid to ensuring fast access to the information, with each carefully reviewed article featuring cross-referencing, references to the most relevant publications in the field, and suggestions for further reading, both introductory as well as more specialized. While the chapters on group theory, integral transforms, Monte Carlo methods, numerical analysis, perturbation theory, and special functions are thoroughly rewritten, completely new content includes sections on commutative algebra, computational algebraic topology, differential geometry, dynamical systems, functional analysis, graph and network theory, PDEs of mathematical physics, probability theory, stochastic differential equations, and variational methods.
Magnetohydrodynamic Stability of Tokamaks
This book bridges the gap between general plasma physics lectures and the real world problems in MHD stability. In order to support the understanding of concepts and their implication, it refers to real world problems such as toroidal mode coupling or nonlinear evolution in a conceptual and phenomenological approach. Detailed mathematical treatment will involve classical linear stability analysis and an outline of more recent concepts such as the ballooning formalism. The book is based on lectures that the author has given to Master and PhD students in Fusion Plasma Physics. Due its strong link to experimental results in MHD instabilities, the book is also of use to senior researchers in the field, i.e. experimental physicists and engineers in fusion reactor science. The volume is organized in three parts. It starts with an introduction to the MHD equations, a section on toroidal equilibrium (tokamak and stellarator), and on linear stability analysis. Starting from there, the ideal MHD stability of the tokamak configuration will be treated in the second part which is subdivided into current driven and pressure driven MHD. This includes many examples with reference to experimental results for important MHD instabilities such as kinks and their transformation to RWMs, infernal modes, peeling modes, ballooning modes and their relation to ELMs. Finally the coverage is completed by a chapter on resistive stability explaining reconnection and island formation. Again, examples from recent tokamak MHD such as sawteeth, CTMs, NTMs and their relation to disruptions are extensively discussed.
Modern Nucleophilic Aromatic Substitution
This book provides a comprehensive overview of nucleophilic aromatic substitutions, focusing on the mechanistic and synthetic features that govern these reactions. The first chapter presents a detailed mechanistic analysis of the factors determining the feasibility of SNAr substitutions, providing decisive information to predict regioselectivity of many reactions and to define the conditions for concerted SNAr processes. Reflecting the key role played by these species as intermediates in most SNAr reactions, chapter 2 then discusses the chemistry of anionic sigma-complexes. Chapter 3 describes the concept of superelectrophilicity in SNAr substitutions, as it has recently emerged from the reactivity of strongly electron-deficient aromatic and heteroaromatic structures. The numerous synthetic applications are considered in depth in the chapters 4 and 5 that follow on intermolecular and intramolecular nucleophilic aromatic substitutions. Then, chapter 6 focuses on substitutions proceeding formally through displacement of a hydride ion, a hot topic in the field. The final chapter brings together concise yet comprehensive discussions surrounding SNAr photosubstitutions, radical substitutions, and ANRORC substitutions. Authored by a highly respected chemist who has contributed greatly to the field over the past two decades, this is a valuable information source for all organic chemists working in academia or the pharmaceutical and agrochemical industries.
Exploring the Solar System
The exploration of our solar system is one of humanity's greatest scientific achievements. The last fifty years in particular have seen huge steps forward in our understanding of the planets, the sun, and other objects in the solar system. Whilst planetary science is now a mature discipline – involving geoscientists, astronomers, physicists, and others – many profound mysteries remain, and there is indeed still the tantalizing possibility that we may find evidence of life on another planet in our system.Drawing upon the latest results from the second golden age of Solar System exploration, author Peter Bond provides an authoritative and up-to-date account of the planets, satellites and smaller debris that orbit the Sun. Written in an informal style, with minimal use of mathematics, this book is the ideal introductory text for non-science students and other readers with little or no science background. With the aid of numerous illustrations, many in full colour, this exciting book brings to life the weird and wonderful worlds that populate our corner of the Universe. This book: Assumes no background in physics , astronomy or mathematics Carefully explains key concepts Gives balanced coverage to areas of controversy or uncertainty in planetary science Is in in full color throughout and richly illustrated An interview with Peter can be found at http://wisciblog.com/2012/02/28/exploring-the-solar-system/
Engineering Principles in Biotechnology
This book is a short introduction to the engineering principles of harnessing the vast potential of microorganisms, and animal and plant cells in making biochemical products. It was written for scientists who have no background in engineering, and for engineers with minimal background in biology. The overall subject dealt with is process. But the coverage goes beyond the process of biomanufacturing in the bioreactor, and extends to the factory of cell’s biosynthetic machinery. Starting with an overview of biotechnology and organism, engineers are eased into biochemical reactions and life scientists are exposed to the technology of production using cells. Subsequent chapters allow engineers to be acquainted with biochemical pathways, while life scientist learn about stoichiometric and kinetic principles of reactions and cell growth. This leads to the coverage of reactors, oxygen transfer and scale up. Following three chapters on biomanufacturing of current and future importance, i.e. cell culture, stem cells and synthetic biology, the topic switches to product purification, first with a conceptual coverage of operations used in bioseparation, and then a more detailed analysis to provide a conceptual understanding of chromatography, the modern workhorse of bioseparation. Drawing on principles from engineering and life sciences, this book is for practitioners in biotechnology and bioengineering. The author has used the book for a course for advanced students in both engineering and life sciences. To this end, problems are provided at the end of each chapter.
Handbook of Coal Analysis
Provides users with everything they need to know about testing and analysis of coal Includes new coverage on environmental issues and regulations as related to coal Provides the reader with the necessary information about testing and analyzing coal and relays the advantages and limitations in understanding the quality and performance of coal Explains the meaning of test results and how these results can predict coal behavior and its corresponding environmental impact during use Includes a comprehensive Glossary which defines items in straightforward language that enable readers to better understand the terminology related to coal Treats issues related to sampling, and accuracy and precision of analysis
Introduction to Population Ecology
Introduction to Population Ecology, 2nd Edition is a comprehensive textbook covering all aspects of population ecology. It uses a wide variety of field and laboratory examples, botanical to zoological, from the tropics to the tundra, to illustrate the fundamental laws of population ecology. Controversies in population ecology are brought fully up to date in this edition, with many brand new and revised examples and data. Each chapter provides an overview of how population theory has developed, followed by descriptions of laboratory and field studies that have been inspired by the theory. Topics explored include single-species population growth and self-limitation, life histories, metapopulations and a wide range of interspecific interactions including competition, mutualism, parasite-host, predator-prey and plant-herbivore. An additional final chapter, new for the second edition, considers multi-trophic and other complex interactions among species. Throughout the book, the mathematics involved is explained with a step-by-step approach, and graphs and other visual aids are used to present a clear illustration of how the models work. Such features make this an accessible introduction to population ecology; essential reading for undergraduate and graduate students taking courses in population ecology, applied ecology, conservation ecology, and conservation biology, including those with little mathematical experience.
Fundamentals of Continuum Mechanics
A concise introductory course text on continuum mechanics Fundamentals of Continuum Mechanics focuses on the fundamentals of the subject and provides the background for formulation of numerical methods for large deformations and a wide range of material behaviours. It aims to provide the foundations for further study, not just of these subjects, but also the formulations for much more complex material behaviour and their implementation computationally. This book is divided into 5 parts, covering mathematical preliminaries, stress, motion and deformation, balance of mass, momentum and energy, and ideal constitutive relations and is a suitable textbook for introductory graduate courses for students in mechanical and civil engineering, as well as those studying material science, geology and geophysics and biomechanics. A concise introductory course text on continuum mechanics Covers the fundamentals of continuum mechanics Uses modern tensor notation Contains problems and accompanied by a companion website hosting solutions Suitable as a textbook for introductory graduate courses for students in mechanical and civil engineering