Прочая образовательная литература
Различные книги в жанре Прочая образовательная литератураPharmaceutical Amorphous Solid Dispersions
Providing a roadmap from early to late stages of drug development, this book overviews amorphous solid dispersion technology – a leading platform to deliver poorly water soluble drugs, a major hurdle in today’s pharmaceutical industry. • Helps readers understand amorphous solid dispersions and apply techniques to particular pharmaceutical systems • Covers physical and chemical properties, screening, scale-up, formulation, drug product manufacture, intellectual property, and regulatory considerations • Has an appendix with structure and property information for polymers commonly used in drug development and with marketed drugs developed using the amorphous sold dispersion approach • Addresses global regulatory issues including USA regulations, ICH guidelines, and patent concerns around the world
Earth's Climate Evolution
To understand climate change today, we first need to know how Earth’s climate changed over the past 450 million years. Finding answers depends upon contributions from a wide range of sciences, not just the rock record uncovered by geologists. In Earth’s Climate Evolution, Colin Summerhayes analyzes reports and records of past climate change dating back to the late 18th century to uncover key patterns in the climate system. The book will transform debate and set the agenda for the next generation of thought about future climate change. The book takes a unique approach to the subject providing a description of the greenhouse and icehouse worlds of the past 450 million years since land plants emerged, ignoring major earlier glaciations like that of Snowball Earth, which occurred around 600 million years ago in a world free of land plants. It describes the evolution of thinking in palaeoclimatology and introduces the main players in the field and how their ideas were received and, in many cases, subsequently modified. It records the arguments and discussions about the merits of different ideas along the way. It also includes several notes made from the author’s own personal involvement in palaeoclimatological and palaeoceanographic studies, and from his experience of working alongside several of the major players in these fields in recent years. This book will be an invaluable reference for both undergraduate and postgraduate students taking courses in related fields and will also be of interest to historians of science and/or geology, climatology and oceanography. It should also be of interest to the wider scientific and engineering community, high school science students, policy makers, and environmental NGOs. Reviews: «Outstanding in its presentation of the facts and a good read in the way that it intersperses the climate story with the author's own experiences. [This book] puts the climate story into a compelling geological history.» -Dr. James Baker «The book is written in very clear and concise prose, [and takes] original, enlightening, and engaging approach to talking about 'ideas' from the perspective of the scientists who promoted them.» -Professor Christopher R. Scotese «A thrilling ride through continental drift and its consequences.» – Professor Gerald R. North «Written in a style and language which can be easily understood by laymen as well as scientists.» – Professor Dr Jörn Thiede «What makes this book particularly distinctive is how well it builds in the narrative of change in ideas over time.» – Holocene book reviews, May 2016 «This is a fascinating book and the author’s biographical approach gives it great human appeal.» – E Adlard
Receptor Biology
This book is geared to every student in biology, pharmacy and medicine who needs to become familiar with receptor mediated signaling. The text starts with explaining some basics in membrane biochemistry, hormone biology and the concept of receptor based signaling as the main form of communication between cells and of cells with the environment. It goes on covering each receptor superfamily in detail including their structure and evolutionary context. The last part focusses exclusively on examples where thorough knowledge of receptors is critical: pharmaceutical research, developmental biology, neurobiology and evolutionary biology. Richly illustrated, the book is perfectly suited for all courses covering receptor based signaling, regardless whether they are part of the biology, medicine or pharmacology program.
Inorganic Syntheses
This volume of Inorganic Syntheses spans the preparations of wide range of important inorganic, organometallic and solid-state compounds. The volume is divided into 6 chapters. The first chapter contains the syntheses of some key early transition metal halide clusters and the very useful mononuclear molybdenum(III) synthon, MoCl3(THF)3. Chapter 2 covers the synthesis of a number of cyclopentadienyl compounds, including a novel route to sodium and potassium cyclopentadienide, MC5H5. Chapter 3 details synthetic procedures for a range of metal-metal bonded compounds, including several with metal-metal multiple bonds. Chapter 4 contains procedures for a range of early and late transition metal compounds, each a useful synthon for further synthetic elaboration. Chapter 5 deals with the synthesis of a number of main group compounds and ligands, while Chapter 6 covers teaching laboratory experiments.
Klassische Mechanik
Das Buch behandelt die klassische Punktmechanik und die Mechanik starrer Korper in den Newtonschen, Lagrangeschen und Hamiltonschen Formulierungen sowie die Schwingungs- und Wellenlehre und die relativistische Mechanik. Die wichtigsten Prinzipien der Mechanik werden nicht nur vorgestellt, sondern mit zahlreichen, uber Standardaufgaben hinausgehenden Beispielen praktisch angewendet. Damit konnen die Leserinnen und Leser die Vielfalt der Mechanik kennenlernen und die mathematischen Methoden einuben, die in fortgeschrittenen Kursen vorausgesetzt werden. Interaktive MATLAB-Applikationen und fotorealistische Animationen mechanischer Probleme veranschaulichen auch kompliziertere Sachverhalte. Aus Rezensionen zu fruheren Auflagen: 'Auch die Durchmischung des Stoffes mit anschaulichen Beispielen und der gut lesbare Text werden diese Ausgabe der Klassischen Mechanik in den Bestsellerlisten halten.' (Internationale Mathematische Nachrichten) 'Die Ausgewogenheit in Theorie und Anwendungen hilft, die klassische Mechanik als das zu erkennen, was sie wirklich ist.' (Optik) Stimmen von Hochschullehrern zu fruheren Auflagen: '… ist das Buch von einer bestechenden Didaktik. Das au?ert sich im Sprachstil, der dem Leser die Begeisterung des Autors unmittelbar mitteilt …' '… mit allergro?ter – wissenschaflicher wie padagogischer – Sorgfalt …' '… ausgewogen in Theorie und Anwendungsbeispielen …'
Semiconductor Electrochemistry
Providing both an introduction and an up-to-date survey of the entire field, this text captivates the reader with its clear style and inspiring, yet solid presentation. The significantly expanded second edition of this milestone work is supplemented by a completely new chapter on the hot topic of nanoparticles and includes the latest insights into the deposition of dye layers on semiconductor electrodes. In his monograph, the acknowledged expert Professor Memming primarily addresses physical and electrochemists, but materials scientists, physicists, and engineers dealing with semiconductor technology and its applications will also benefit greatly from the contents.
Acetylsalicylic Acid
Written by a leading expert on Aspirin-related research, this is the most comprehensive treatise on the pharmacological effects and clinical applications of one of the most successful drugs ever. The text is written with a wide audience in mind, and to be readily understandable for clinicians, pharmacists, biomedical researchers and pharmacologists alike. This second, completely revised edition contains the latest results of clinical and pharmacological research on Acetylsalicylic acid, addressing the multiple pharmacological properties of this famous drug with a balanced view on their translation into clinical practice, including prevention from cardiovascular diseases and colorectal cancer.
Phase Transformations
This book is part of a set of books which offers advanced students successive characterization tool phases, the study of all types of phase (liquid, gas and solid, pure or multi-component), process engineering, chemical and electrochemical equilibria, and the properties of surfaces and phases of small sizes. Macroscopic and microscopic models are in turn covered with a constant correlation between the two scales. Particular attention has been given to the rigor of mathematical developments. This fifth volume is devoted to the study of transformations and equilibria between phases. First- and second-order pure phase transformations are presented in detail, just as with the macroscopic and microscopic approaches of phase equilibria. In the presentation of binary systems, the thermodynamics of azeotropy and demixing are discussed in detail and applied to strictly-regular solutions. Eutectic and peritectic points are examined, as well as the reactions that go with them. The study of ternary systems then introduces the concepts of ternary azeotropes and eutectics. For each type of solid-liquid system, the interventions of definite compounds with or without congruent melting are taken into account. The particular properties of the different notable points of a diagram are also demonstrated.
Chemical Equilibria
The book offers advanced students, in 7 volumes, successively characterization tools phases, the study of all types of phase, liquid, gas and solid, pure or multi-component, process engineering, chemical and electrochemical equilibria, the properties of surfaces and phases of small sizes. Macroscopic and microscopic models are in turn covered with a constant correlation between the two scales. Particular attention was given to the rigor of mathematical developments. Besides some very specialized books, the vast majority of existing works are intended for beginners and therefore limited in scope. There is no obvious connection between the two categories of books, general books does not go far enough in generalizing concepts to enable easy reading of advanced literature. The proposed project aims to give readers the ability to read highly specialized publications based on a more general presentation of the different fields of chemical thermodynamics. Consistency is ensured between the basic concepts and applications. So we find, in the same work, the tools, their use and comparison, for a more general macroscopic description and a microscopic description of a phase.
Human Neuroanatomy
Human Neuroanatomy, 2nd Edition is a comprehensive overview of the anatomy of the human brain and spinal cord. The book is written at a level to be of use as a text for advanced students and a foundational reference for researchers, clinicians in the field. Building on the foundations of first edition, this revision looks to increase user-friendliness and clinical applicability through improved figures and the addition of illustrative case studies. Written by James R. Augustine, with decades of experience teaching and researching in the field, Human Neuroanatomy, authoritatively covers this fundamental area of study within the neurosciences.