The at a Glance series is popular among medical students, residents, junior doctors and health professionals for its concise and clear approach and excellent illustrations. Each topic is concisely covered in a double-page spread with color summary diagrams accompanied by explanatory text. Covering a wide range of topics, books in the at a Glance series are ideal as introductory subject texts or for revision purposes, and are useful throughout medical and nursing training and beyond. Everything you need to know about Neonatology… at a Glance! Written by leading international experts, this accessible overview provides need-to-know information on perinatal medicine, the normal newborn infant, preterm infants and neonatal problems encountered in Intensive Care Units, and their management. Neonatology at a Glance: Provides coverage of the important conditions you will encounter Addresses ethical issues, the death of an infant, quality assurance and evidence-based medicine Includes invaluable advice on practical procedures, in text and diagrammatic form Has been updated to reflect current practice in both the UK and US Neonatology at a Glance is the perfect guide for all health professionals looking after newborn infants, including paediatric trainees, medical students, neonatal nurse practitioners and neonatal nurses, therapists and midwives. For neonatologists, pediatricians and nurse tutors it is a valuable resource to assist with teaching.
** New revised second edition now available, with errors corrected and content fully updated ** The second edition of the classic text has been revised and extended to meet the needs of today’s practising and training MRI technologists who intend to sit for the American Registry of Magnetic Resonance Imaging Technologists (ARMRIT) examination. It provides Q&As on topics listed in the content specifications offered by the American Registry for Radiologic Technologists (AART) and offers the user with a comprehensive review of the principles and applications of MRI to prepare them for the examination.
Beautifully presented, and now in full colour, the sixth edition of Essential Endocrinology and Diabetes is fully up-to-date with the latest knowledge and concepts on the workings of the endocrine system. It explains the key principles of endocrine physiology in an easy reading style popular with students, clinicians and scientists. The invaluable background on basic science and investigation, including new molecular techniques, provides the foundation for detailed discussion of the diagnosis and management of clinical endocrine disorders and diabetes. The teaching style and presentation has been strengthened throughout, and includes learning objectives and “recap” links at the beginning of each chapter that remind the reader of key findings and principles, while cross-referencing makes it easy to locate related information quickly and efficiently. There are also more case studies, with detailed answers applying theory to practice. Essential Endocrinology and Diabetes is the perfect resource for a course on endocrinology and diabetes, as part of USMLE teaching, and an on-going companion during postgraduate clinical and scientific study. It is accompanied by a FREE enhanced Wiley Desktop Edition – the interactive, digital version of the book – featuring downloadable text and images, highlighting and note taking facilities, book-marking, cross-referencing, in-text searching, and linking to references and glossary terms.
Pharmacogenomics is the basis of personalized medicine which will be the medicine of the future. Through both reducing the numbers of adverse drug reactions and improving the use of existing drugs in targeted populations, pharmacogenomics represents a real advance on traditional therapeutic drug monitoring. Pharmacogenomics in Clinical Therapeutics provides an introduction to the principles of pharmacogenomics before addressing the pharmacogenomic aspects of key therapeutic areas such as warfarin therapy, cancer chemotherapy, therapy with immunosuppressants, antiretroviral therapy, and psychoactive drugs. It also includes methods of pharmacogenomic testing and the pharmacogenomic aspects of drug–drug interactions. From a team of expert contributors, Pharmacogenomics in Clinical Therapeutics is a comprehensive overview of the current state of pharmacogenomics in pharmacotherapy for all clinicians, pharmacologists and clinical laboratory professionals. It is also a guide for practicing clinicians and health care professionals to the basic principles of pharmacogenomics, laboratory tests currently available to aid clinicians, and the future promise of this developing field.
Anke-Hilse Maitland-van der Zee
This resource provides thorough coverage of pharmacogenetics and its impact on pharmaceuticals, therapeutics, and clinical practice. It opens with the basics of pharmacogenetics, including drug disposition and pharmacodynamics. The following section moves into specific disease areas, including cardiovascular, psychiatry, cancer, asthma/COPD, adverse drug reactions, transplantation, inflammatory bowel disease, and pain medication. Clinical practice and ethical issues make up the third section, with the fourth devoted to technologies like genotyping, genomics, and proteomics. In the fifth part, chapters discuss the impact of key regulatory issues on the pharmaceutical industry.
The opportunities and challenges of using dendrimers to improve drug delivery Among pharmaceutical and biomedical researchers, the use of dendrimers in drug delivery systems has attracted increasing interest. In particular, researchers have noted that the volume of a dendrimer increases when it has a positive charge. If this property can be applied effectively, dendrimers have enormous potential in drug delivery systems, directly supplying medication to targeted human organs. With contributions from an international team of pioneers and experts in dendrimer research, this book provides a comprehensive overview of the latest research efforts in designing and optimizing dendrimer-based drug delivery systems. The book analyzes key issues, demonstrating the critical connections that link fundamental concepts, design, synthesis, analytical methodology, and biological assessment to the practical use of dendrimers in drug delivery applications. Topics covered include: Dendrimer history Synthesis Physicochemical properties Principles of drug delivery Applications in diverse biomedical fields Dendrimer-Based Drug Delivery Systems reflects the authors' thorough review and analysis of the current literature as well as their own firsthand experience in the lab. Readers will not only discover the current state of the science, but also gain valuable insights into fruitful directions for future research. References at the end of each chapter serve as a gateway to the growing body of literature in the field, enabling readers to explore each individual topic in greater depth. Pharmaceutical and biomedical researchers will find this book a unique and essential guide to the opportunities, issues, and challenges involved in fully exploiting the potential of dendrimers to improve drug delivery.
Diabetic Foot Care: Case Studies in Clinical Management uses a 100% illustrated patient case study format to demonstrate the multidisciplinary care and clinical management of patients with feet and lower limb problems as a result of diabetes. Every case has colour illustrations highlighting both the initial presentation of the foot, right through to treatment and long term follow-up care. Of particular focus are the management problems, barriers to effective care, preventable mistakes, unnecessary delays in presentations, challenging situations, conflicts, dilemmas and solutions that podiatrists and diabetic specialists face. Sections in the book include: Neuropathic and neuroischaemic foot, neuropathic ulcers, ischaemic ulcers, infections, gangrene, traumatic injuries, Charcot's osteoarthropathy, dermatological problems associated with diabetes, painful neuropathy, diabetic foot emergencies, angiology and foot surgery/amputation. With key points and summaries at the beginning and end of each section, this book is clear and easy to navigate, making it an ideal tool for diabetes specialists, diabetes nurses and podiatrists.
Foundations of Health Care Management Leaders and managers throughout the health care system are facing ever more challenging changes in the way care is delivered, paid for, and evaluated. Foundations of Health Care Management: Principles and Methods offers an innovative, concise, reader-friendly introduction to health care management and administration. It addresses the need for new skills in managers of health care facilities and for those planning to enter health care management positions. The book covers such critical topics as leadership training, change management, conflict management techniques, culture building, quality improvement, and communications skills, as well as collaboration in the improvement of population health. Foundations of Health Care Management also concentrates on innovations and describes steps in the transition to more decentralized and creative approaches to the management of health care facilities. The book covers physician management from the physician's viewpoint, a valuable perspective for health care managers. The book serves important dual purposes for faculty and students by providing both insights into the health care field as well as foundational content on essential management and leadership competencies. A full set of support materials is available for instructors at the book's companion Web site.
Practical drug development approaches presented by leading experts Designed to support the development of new, effective therapeutics, Topical and Transdermal Drug Delivery: Principles and Practice explains the principles underlying the field and then demonstrates how these principles are put into practice in the design and development of new drug products. Drawing together and reviewing the latest research findings, the book focuses on practical, tested, and proven approaches that are backed by industry case studies and the authors' firsthand experience. Moreover, the book emphasizes the mechanistic information that is essential for successful drug product development. Topical and Transdermal Drug Delivery: Principles and Practice is divided into two parts: Part One, Current Science, Skin Permeation, and Enhancement Approaches, offers readers a fundamental understanding of the underlying science in the field. It describes the principles and techniques needed to successfully perform experimental approaches, covering such issues as skin permeation, enhancement, and assessment. Part Two, Topical and Transdermal Product Development, guides readers through the complete product development process from concept to approval, offering practical tips and cautions from experts in the field. This part also discusses regulations that are specific to the development of dermal drug products. The final chapter explores current and future trends, forecasting new development techniques and therapeutics. Throughout the book, the authors clearly set forth the basic science and experimental procedures, making it possible for researchers to design their own experimental approaches and accurately interpret their results. With contributions from experienced drug researchers, this text is highly recommended for all researchers involved in topical and transdermal product development who need to know both the state of the science and the standards of practice.
Based on the authors' teaching and research at the Johns Hopkins Bloomberg School of Public Health and the Keck School of Medicine of the University of Southern California, the second edition of this landmark text offers a general framework for students, researchers, practitioners, and policymakers for learning about vulnerable populations. It contains in-depth data and information on major health and health care disparities by race or ethnicity, socioeconomic status, and health insurance coverage. It is thoroughly updated to include the latest data and trends and provides a detailed synthesis of recent and increasingly expansive programs and initiatives to remedy these disparities. To keep current with recent trends it incorporates the latest Healthy People 2020 objectives, includes new sections on real-world clinical examples, and discusses the impact of health care reform on vulnerable populations. The book's Web site includes instructor's materials that may be downloaded. Praise for the First Edition of Vulnerable Populations in the United States «An excellent primer for undergraduates and graduate students interested in vulnerable populations and health disparities.» —New England Journal of Medicine «Combines thoughtful, coherent theory with a large amount of information available in a single source. It will prove to be a valuable resource for policymakers, researchers, teachers, and students alike for years to come.» —Journal of the American Medical Association «A very worthwhile read for health care administrators, health policy analysts, public health and health promotion practitioners, students of public health, and health researchers.» —Inquiry «It makes clear that, for political, social, and economic (as well as moral) reasons, the country must increasingly make vulnerable populations a national health policy priority.» —Journal of Health Care for the Poor and Underserved «I have reviewed a number of books looking for meaningful content to help my students understand and work with vulnerable populations. This is the most comprehensive, yet understandable book on the topic.» —Doody's Reviews «Provides much-needed guidance to policymakers challenged with providing solutions to this embarrassing issue in the United States.» —F. Douglas Scutchfield, MD, Peter P. Bosomworth Professor of Health Services Research and Policy, University of Kentucky Companion Web site: www.josseybass.com/go/shi