IN THE BEGINNING. Welby Thomas Cox, Jr.

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Название IN THE BEGINNING
Автор произведения Welby Thomas Cox, Jr.
Жанр Историческое фэнтези
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Издательство Историческое фэнтези
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isbn 9781649693266



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impossible.

       DISCIPLINARY DIVIDE

      Looking closer, the divide between those who support a terrestrial and those supporting an oceanic origin is split between disciplines. Synthetic chemists generally favor a continental origin and geologists and biologist mostly deep-sea hydrothermal vents. Chemists argue it’s impossible to do the chemistry in hydrothermal vents, while biologists argue that the terrestrial chemistry proposed just isn’t like anything seen in biochemistry and doesn’t narrow the gap between geochemistry and biochemistry.

      So, is there a way to unite the disciplines? ‘At the moment there is not much common ground between these ideas,’ Lane says. Deamer agrees. ‘At this point, all we can say is that everyone has the right to do a plausibility judgement on the basis of their ideas but then they also must do experimental and observational tests.’

       The smaller problems will be solvable – that’s what gets me out of bed in the morning. (WTC)

      What is needed is that killer piece of evidence or experiment that could join the dots together and explain how and where life began from a prebiotic world. ‘It would really be a big breakthrough if we can find a ribozyme among all of these trillions of random polymers that we are making,’ suggests Deamer. Ribozymes are RNA catalysts that are part of the cell’s protein-synthesis machinery but are candidates for the first self-replicating molecules.

      Further evidence to support the origins of life in deep sea hydrothermal vents centers on showing a plausible set of metabolic steps leading to complex molecules. At JPL, they are looking at how amino acid behave in their chemical gardens, according to Barge. ‘We are working on making an amino acid, and then seeing whether [amino acids] get stuck in the chimneys and whether you can concentrate them and maybe make some peptides.’

      ‘There are problems and difficulties,’ Lane acknowledges. ‘Can we really make carbon dioxide react with hydrogen to make more complex molecules like amino acids and nucleotides? I’m fairly confident we can do that, but I am aware we have not demonstrated that yet.’ Other difficult questions include whether lipid membranes can be stabilized in seawater with its high calcium and magnesium ion concentrations. But says Lane the big problem of the thermodynamic driving force is solved by hydrothermal vents. ‘Which gives me confidence that the smaller problems will be solvable in that context too, even if they look difficult now – that’s what gets me out of bed in the morning.’

      Of course, there is one other possibility – that life did not start on earth at all. Panspermia – the theory that life was seeded from space, seems eccentric, but not everybody counts it out. ‘An argument can be made that life actually began on Mars,’ according to Deamer, because it was first to cool down to a temperature which could support life.

      Whether this is the case or not, life elsewhere is certainly feasible. Jupiter’s moon Europa and Saturn’s moon Enceladus are candidates because they both have oceans beneath icy shells. In the next five years, Nasa is planning to send a space probe to both these moons to look for signs of life. Understanding our own origin story could help us work out where to look.

      Chapter 5

      New Study Outlines 'Water World' Theory of Life's Origin

      Life took root more than four billion years ago on our nascent Earth, a wetter and harsher place than now, bathed in sizzling ultraviolet rays. What started out as simple cells ultimately transformed into slime molds, frogs, elephants, humans and the rest of our planet's living kingdoms. How did it all begin?

      A new study from researchers at NASA's Jet Propulsion Laboratory in Pasadena, Calif., and the Icy Worlds team at NASA's Astrobiology Institute, based at NASA's Ames Research Center in Moffett Field, Calif., describes how electrical energy naturally produced at the sea floor might have given rise to life. While the scientists had already proposed this hypothesis -- called "submarine alkaline hydrothermal emergence of life" -- the new report assembles decades of field, laboratory, and theoretical research into a grand, unified picture.

      According to the findings, which also can be thought of as the "water world" theory, life may have begun inside warm, gentle springs on the sea floor, at a time long ago when Earth's oceans churned across the entire planet. This idea of hydrothermal vents as possible places for life's origins was first proposed in 1980 by other researchers, who found them on the sea floor near Cabo San Lucas, Mexico. Called "black smokers," those vents bubble with scalding hot, acidic fluids. In contrast, the vents in the new study -- first hypothesized by scientist Michael Russell of JPL in 1989 -- are gentler, cooler and percolate with alkaline fluids. One such towering complex of these alkaline vents was found serendipitously in the North Atlantic Ocean in 2000 and dubbed the Lost City.

      "Life takes advantage of unbalanced states on the planet, which may have been the case billions of years ago at the alkaline hydrothermal vents," said Russell. "Life is the process that resolves these disequilibria." Russell is lead author of the new study, published in the April issue of the journal Astrobiology.

      Other theories of life's origins describe ponds, or "soups," of chemicals, pockmarking Earth's battered, rocky surface. In some of those chemical soup models, lightning or ultraviolet light is thought to have fueled life in the ponds.

      The water world theory from Russell and his team says that the warm, alkaline hydrothermal vents maintained an unbalanced state with respect to the surrounding ancient, acidic ocean -- one that could have provided so-called free energy to drive the emergence of life. In fact, the vents could have created two chemical imbalances. The first was a proton gradient, where protons -- which are hydrogen ions -- were concentrated more on the outside of the vent's chimneys, also called mineral membranes. The proton gradient could have been tapped for energy -- something our own bodies do all the time in cellular structures called mitochondria.

      The second imbalance could have involved an electrical gradient between the hydrothermal fluids and the ocean. Billions of years ago, when Earth was young, its oceans were rich with carbon dioxide. When the carbon dioxide from the ocean and fuels from the vent -- hydrogen and methane -- met across the chimney wall, electrons may have been transferred. These reactions could have produced more complex carbon-containing, or organic compounds -- essential ingredients of life as we know it. Like proton gradients, electron transfer processes occur regularly in mitochondria.

      "Within these vents, we have a geological system that already does one aspect of what life does," said Laurie Barge, second author of the study at JPL. "Life lives off proton gradients and the transfer of electrons."

      As is the case with all advanced life forms, enzymes are the key to making chemical reactions happen. In our ancient oceans, minerals may have acted like enzymes, interacting with chemicals swimming around and driving reactions. In the water world theory, two different types of mineral "engines" might have lined the walls of the chimney structures.

      "These mineral engines may be compared to what's in modern cars," said Russell.

      "They make life 'go' like the car engines by consuming fuel and expelling exhaust. DNA and RNA, on the other hand, are more like the car's computers because they guide processes rather than make them happen."

      One of the tiny engines is thought to have used a mineral known as green rust, allowing it to take advantage of the proton gradient to produce a phosphate-containing molecule that stores energy. The other engine is thought to have depended on a rare metal called molybdenum. This metal also is at work in our bodies, in a variety of enzymes. It assists with the transfer of two electrons at a time rather than the usual one, which is useful in driving certain key chemical reactions.

      "We call molybdenum the Douglas Adams element," said Russell, explaining that the atomic number of molybdenum is 42, which also happens to be the answer to the "ultimate question of life, the universe and everything" in Adams' popular book, "The Hitchhiker's Guide to the Galaxy." Russell joked, "Forty-two may in fact be one answer to the ultimate question of life!"

      The team's origins of life theory applies not just to Earth but also