Zero Disease. Angelo Barbato

activities that were beginning to emerge. These were mostly surgical, as a result of the revolutionary scientific discoveries and practices of the birth era of the foundations for anesthesia, microbiology, antisepsis and asepsis, but also diagnostic laboratory support, followed by diagnostic radiology (X-ray, 1901 Nobel prize), to which electrocardiographic diagnostics⁷ would be added soon after (Einthoven, 1908).

      In order to organize health care in addition to acute patient management and thus urgency/ emergency, you need an increasing ability to manage chronic illness through a holistic vision that includes active handling of the disease, more often chronic diseases to be centered on prevention.

      In recent years the traditional and hierarchical health care model that is identified with hospital care has began to falter, not only due to the high cost of energy, technology and management but also because of the profound epidemiological changes in diseases. Traditionally, the cure of acute illnesses has reportedly developed a standby medicine in the top-down hospital context, a facility increasingly dedicated to users, emergency and to the treatment of high intensity and in need of advanced technologies. The hospital has become ineffective for the treatment of rising widespread chronic diseases in need of multidimensional interventions, also linked with social health.

      The increase in life expectancy with the progressive ageing of the population has led to the augmentation of chronic degenerative and debilitating diseases, for which the traditional hospital standby model is inadequate.

      The attempt to create within the hospital outpatient sectors for specialized external uses has proved unsuccessful for a number of reasons: the structural and hospital management costs are too high for such activities, and the type of performance is completely different since the acute patient must be treated in the hospital and the chronically ill should be treated in the zone, through the enhancement of organizational models characterized by prevention.

      Merging the management of activities for acute disease with the management of the activities for chronic illness inside the hospital deviates high-tech and urgency resources from interventions for the acutely ill. The center of gravity of care for chronic conditions needs to be moved into the territory, with the need for increased effectiveness also through avoidance interventions. Prevention becomes the pillar of the distributive model of territorial health care: not only due to its undisputed importance in the promotion and maintenance of health, but also for the better utilization of resources, resulting in cost reduction. The new strategies for the integration of health policies must necessarily take into account environmental sustainability.

      After a period of constant evolution and adaptation of the specific structure for increasingly accurate, effective, technically advanced and prognostically favorable treatments, - the hospital - the focus, has opened itself towards the territorial zone for several reasons.

      The hospital is a highly sophisticated structure with high technological trends, high management costs only justifiable for performance-intensive care given to a patient in acute emergency and made possible only in a protected environment.

      The territory consequently gains importance not only to provide care and treatment to low-intensity patients and to guarantee care continuity and the patient's recovery. But above all, to prevent and anticipate the disease (early detection!). In addition, the territory also represents an important input filter and selector for hospitalization.

       The hospital, by vocation, treats (or should treat!) 100% of the acutely ill, while health outside the hospital treats (or should treat!) mainly the healthy to ensure a minimal occurrence of sickness.

      The primary care target is therefore made up of 40% of healthy individuals, 40% of healthy individuals with risk factors and the remaining 20% of ill individuals (of which 10% have disabilities).

      The hospital's mission is maximum repair and cure of the individual's biological damage, while the mission of the zone is to avoid health damage through multiple strategies on population health, even informing and educating people of the best way to live .

      In a distributed model of medicine of the territory, health professionals and family physicians are the central figures in order to achieve a proactive medicine. Proactive medicine is centered on the promotion of good health and the prevention of bad health. The health of a community is determined by socioeconomic and environmental factors, lifestyle and access to services. It is evident that only the model of distributed medicine in the territory with a central role in prevention can ensure the implementation of a wide range of initiatives, projects and policies necessary for effective health promotion.

      Hence, the necessity emerges for an integrated strategy between governmental bodies and non-governmental bodies, in the possible fields for regional action. From the action of doctors on the territory and in schools, to interventions by the public authorities through training activities based on epidemiological evidence. The concept of integration is essential and must be developed in a distributed model of Zero Zone, cornerstones of which is home medicine and telemedicine: i.e. trying to bring care closer to the patient-citizen.

      Modern medicine (with the exception of acute illnesses) should become "initiative-based", since it must not be the citizen-patient to contact the hospital system but the Zero Zone to take the burden of health in a proactive manner by trying to prevent the development of chronic disease. Proactive medicine has the primary objective of avoiding the disease (primary interception with its information tools, health education, empowerment, control and information on the risk factors). Secondly, its tasks are early recognition of onset pathological conditions (secondary prevention) through targeted interventions and rapid, highly qualified, epidemiological study and monitoring of collective health, determinants of well-being and illness.

      To develop the model of Zero Zone, synonymous of active and preventive approach, multidisciplinary, integrated, non-hierarchical, structured network; high computerization (internet of things) is required. Among the tools in exponential development we find apps, increasingly becoming key elements in the communication between doctor and patient (bidirectional energy binomial), essential for effective therapeutic action thanks to i thets significant synergistic effect.

      The sustainability of the health system in a distributed model that can not be separated from an integration with the social in the Zero Zone logic (sharing economy).

      ZERO Zone is simultaneously a basic and complex operation. The idea is simple: to program a society that tends towards zero entropy. The work to get there is complex since it involves new mental paradigms, new educational models, new business strategies, new administrative measures. Examples are the overcoming of departments of energy, economic development, environment, agriculture, in favor of departments to commons goods or land resources. Smart grids are the digital infrastructures of the Internet of things that allow the connection between energy, communications and logistics. In electrical engineering and telecommunications, a smart grid represents the combining of an information network and an electrical distribution network in such a way as to allow the management of the electrical network in an"intelligent" manner under various aspects or features. In other words, the efficient distribution of electrical energy and a more rational use of energy; thereby minimizing any overloads and variations of the voltage around its nominal value⁸ .

      According to the ideological picture of Jeremy Rifkin, a distributed model (Commons) should be applied to the way in which food and energy are produced and the creation of polluting waste at the end of the fuel cycle is avoided. According to the authors, this also concerns the way in which health care is organized in the territory, through the distributed pillar of prevention (Zero Disease) which can only be formed in the Commons. The smart grid digital health is thus being born.

      In “The zero marginal cost society" Jeremy Rifkin argues that a new economic system is emerging on the world stage, the rise of the Internet of things is giving life to the "Collaborative Commons", the first new economic paradigm to take hold by the advent of capitalism and socialism in the nineteenth century. Collaborative Commons is transforming the way we co-ordinate economic life opening up the possibility to a drastic reduction in income inequality by democratizing the global economy and creating a more environmentally sustainable society.

       In a distributed scenario of the Third Industrial