Клеточные и молекулярные механизмы патогенеза иммуновоспалительных ревматических заболеваний. Марат Зиявдинович Саидов

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простым исчезновением последних, но является важным фактором поддержания и прогрессирования воспаления. Содержание этого уникального феномена состоит в том, что потеря целостности клеточной мембраны и высвобождение внутриклеточного содержимого обуславливают организацию цитопатогенного аутовоспаления и аутоиммунного ответа на DAMP, имеющих все характеристики ауто-АГ.

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