Neonatal Haematology. Irene Roberts

Causes of disseminated intravascular coagulation (DIC) in neonat...

      List of Illustrations

      1 Chapter 1Fig. 1.1 Ontogeny of human haemopoiesis in embryonic and fetal life. AGM, ao...Fig. 1.2 A simplified scheme of the fetal haemopoietic stem and progenitor c...Fig. 1.3 Immunophenotypically defined progenitor populations along the B cel...Fig. 1.4 Diagrammatic representation of the sites and rates of synthesis of ...Fig. 1.5 First trimester (8 weeks) fetal blood film showing the large size o...Fig. 1.6 Second trimester (14 weeks) fetal blood film showing typical erythr...Fig. 1.7 Normal blood film at term. MGG, ×40.Fig. 1.8 Normal preterm red cells at different gestational ages: (a) baby bo...Fig. 1.9 Blood film of a normal preterm baby (born at 28 weeks’ gestation) s...Fig. 1.10 Blood film showing features of hyposplenism resulting from intraut...Fig. 1.11 Blood film from a preterm neonate (born at 25 weeks’ gestation) on...Fig. 1.12 Impact of postnatal age on red cell morphology; blood films from: ...Fig. 1.13 Blood film of a preterm neonate showing normal white cells – two n...Fig. 1.14 Blood film of a healthy preterm neonate born at 25 weeks’ gestatio...Fig. 1.15 Blood film of a well preterm neonate showing a myelocyte and three...Fig. 1.16 Blood film of a preterm neonate with early clinical signs of necro...Fig. 1.17 Blood film of a preterm neonate born at 24 weeks’ gestation showin...Fig. 1.18 Blood film of a healthy term neonate with a normal blood count and...Fig. 1.19 Blood film in maternal chorioamnionitis showing neutrophilia, left...Fig. 1.20 Leucoerythroblastic blood film in a preterm neonate with hypoxic i...

      2 Chapter 2Fig. 2.1 Blood film of a term neonate with anaemia due to parvovirus B19 inf...Fig. 2.2 Bone marrow film of a neonate with Pearson syndrome showing vacuola...Fig. 2.3 Basophilic stippling in a bone marrow erythroblast (centre field) f...Fig. 2.4 Dyserythropoietic erythroblasts in the bone marrow of a neonate wit...Fig. 2.5 Peripheral blood film of a neonate with Pearson syndrome showing va...Fig. 2.6 Peripheral blood film of a neonate with Pearson syndrome showing a ...Fig. 2.7 Congenital dyserythropoietic anaemia (CDA): (a) blood film of a ter...Fig. 2.8 Typical blood film of a term neonate with ABO haemolytic disease of...Fig. 2.9 Blood film of a preterm neonate with ABO HDFN showing large numbers...Fig. 2.10 Blood film of a term neonate with severe Rh HDFN showing large num...Fig. 2.11 Blood film of a preterm neonate with Rh HDFN showing large numbers...Fig. 2.12 Blood film of a term baby with severe Rh HDFN showing dyserythropo...Fig. 2.13 Blood film of a neonate with hereditary spherocytosis showing sphe...Fig. 2.14 (a) Blood film of a neonate with hereditary spherocytosis showing ...Fig. 2.15 Blood films of a neonate with hereditary pyropoikilocytosis and he...Fig. 2.16 Blood film of an older patient with Southeast Asian ovalocytosis s...Fig. 2.17 Blood film of a neonate with oxidative haemolysis due to glucose‐6...Fig. 2.18 Blood film of a neonate with pyruvate kinase (PK) deficiency showi...Fig. 2.19 Blood film of a preterm neonate with haemoglobin Bart’s hydrops fe...Fig. 2.20 Blood film of the mother of the neonate whose film is shown in Fig...Fig. 2.21 High performance liquid chromatography (HPLC) on a BioRad Variant ...Fig. 2.22 HPLC on a BioRad Variant II instrument of a neonate with sickle ce...Fig. 2.23 Blood film of two term neonates with anaemia secondary to fetomate...Fig. 2.24 Kleihauer–Betke test. (a) This image shows maternal red blood cell...Fig. 2.25 Blood film of a term neonate born with severe anaemia (Hb 50 g/l) ...Fig. 2.26 Diagram showing a suggested approach to the diagnosis of neonatal ...Case 2.1, Fig. 1 Blood film. MGG, ×100 objective.Case 2.1, Fig. 2 Bone marrow aspirate. MGG, ×60.Case 2.2, Fig. 1 Blood film. MGG, ×100.Case 2.2, Fig. 2 Bone marrow aspirate. MGG, ×40.Case 2.3, Fig. 1 Blood film. MGG, ×40.Case 2.4, Fig. 1 Blood film. MGG, ×40.Case 2.4, Fig. 2 Blood film. MGG, ×40.Case 2.5, Fig. 1 Blood film. MGG, ×100.Case 2.5, Fig. 2 Bone marrow aspirate. MGG, ×100.Case 2.6, Fig. 1 Blood film of twin 1. MGG, ×100.Case 2.6, Fig. 2 Blood film of twin 2. MGG, ×100.Case 2.7, Fig. 1 Blood film. Based on reference 12. MGG, ×100.Case 2.8, Fig. 1 Blood film. MGG, ×100.Case 2.9, Fig. 1 Blood film. MGG, ×40.Case 2.9, Fig. 2 Kleihauer test. ×100.

      3 Chapter 3Fig. 3.1 Blood film of a preterm neonate with eosinophilia showing two eosin...Fig. 3.2 Blood film of a preterm neonate born at 24 weeks’ gestation showing...Fig. 3.3 Blood film of a preterm neonate with infection by group B Streptoco...Fig. 3.4 Blood film of a term neonate with Pelger–Huët anomaly showing three...Fig. 3.5 Blood film of a term neonate with Pelger–Huët anomaly showing a Pel...Fig. 3.6 Blood film of a preterm neonate showing typical features of a Gram‐...Fig. 3.7 Blood film of a neonate with congenital Listeria monocytogenes infe...Fig. 3.8 Blood film of a neonate with congenital toxoplasmosis showing atypi...Fig. 3.9 Blood film of a preterm neonate born at 26 weeks’ gestation with co...Fig. 3.10 Blood film of a preterm neonate born at 27 weeks’ gestation and fo...Fig. 3.11 Impact of maternal chorioamnionitis on the blood film at birth sho...Fig. 3.12 Blood film of a 3‐week‐old preterm neonate born at 29 weeks’ gesta...Fig. 3.13 Blood film of a preterm neonate with Staphylococcus epidermidis in...Fig. 3.14 Blood film of a neonate with Candida infection showing neutrophil ...Fig. 3.15 Blood film of a preterm neonate with necrotising enterocolitis sho...Fig. 3.16 Blood film of a neonate with congenital cytomegalovirus (CMV) infe...Fig. 3.17 Blood film of a preterm neonate with congenital infection with cox...Fig. 3.18 Blood films in storage disorders: (a) lymphocyte vacuolation in Wo...Fig. 3.19 Blood film of a preterm neonate with IUGR showing increased number...Fig. 3.20 Blood film of a 3‐week‐old term neonate with severe congenital neu...Fig. 3.21 Blood film of a neonate with SCN during an acute infection showing...Fig. 3.22 Blood film of a neonate with Down syndrome showing increased eryth...Fig. 3.23 Blood films of neonates with Down syndrome with TAM: (a) severe TA...Fig. 3.24 Blood film of a term neonate with Down syndrome and TAM showing si...Fig. 3.25 Summary of the phenotypic, immunophenotypic and genetic features o...Fig. 3.26 Blood film of a newborn with congenital AML showing large numbers ...Fig. 3.27 ‘Blueberry muffin’ rash due to leukaemia cutis in a neonate with c...Fig. 3.28 Blood film of a neonate with congenital ALL showing hyperleukocyto...Fig. 3.29 Blood film of a neonate with Noonan syndrome‐associated myeloproli...Case 3.1, Fig. 1 Blood film on first day of life. MGG, ×100 objective.Case