Neurology. Charles H. Clarke

      This edition first published 2022

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       Library of Congress Cataloging‐in‐Publication Data

      Names: Clarke, Charles (Charles R. A.) author. | National Hospital for Neurology & Neurosurgery, Queen Square.

      Title: Neurology: A Clinical Handbook / Charles Clarke.

      Other titles: Neurology.

      Description: Hoboken, NJ : Wiley, 2022. | Based on: Neurology : A Queen Square Textbook / edited by Charles Clarke, Robin Howard, Martin Rossor, Simon Shorvon. Second edition. Chichester, West Sussex, UK ; Hoboken, NJ : |b John Wiley & Sons, Inc., 2016. | Includes bibliographical references and index.

      Identifiers: LCCN 2021054270 (print) | LCCN 2021054271 (ebook) | ISBN 9781119235729 (paperback) | ISBN 9781119235712 (adobe pdf) | ISBN 9781119235705 (epub)

      Subjects: MESH: Nervous System Diseases | Neurology | Handbook

      Classification: LCC RC346 (print) | LCC RC346 (ebook) | NLM WL 39 | DDC 616.8–dc23/eng/20211124

      LC record available at https://lccn.loc.gov/2021054270 LC ebook record available at https://lccn.loc.gov/2021054271

      Cover Design: Wiley

      Cover Image: © Sergey Nivens/Shutterstock

      Preface

      In my training in the 1970s I was guided by many clinicians and also by books. Those large neurology tomes were useful, but it was the smaller texts that gave me insight into clinical practice. One by Dr Bryan Matthews, later Professor of Clinical Neurology at Oxford, was Practical Neurology published in 1963, when Matthews was a general neurologist in Derby. His was a book I could enjoy. Some comments are etched in my memory:

      ‘There are many admirable textbooks of neurology but it is a matter of common observation that they are of more assistance in the passing of written examinations than in the management of practical problems’. Another, quoting Sir Geoffrey Jefferson, remarked ‘ … in life the tracts are not marked in red …’

      And, from Matthews on dizziness: ‘ … there can be few physicians so dedicated to their art that they do not experience a slight decline in spirits on learning that their patient complains of giddiness.…’

      There was thus some logic in taking Neurology: A Queen Square Textbook, Second Edition, the major reference work that I initiated and edited with colleagues, and turning it into this shorter, practical book. I hope this Handbook will serve two purposes. First, it is to be read – each chapter aims to give a brief overview of an area of neurology. Secondly, this book, a synopsis of our subject, provides a pointer to Neurology: A Queen Square Textbook in its forthcoming Third Edition, a completely separate project that has been fully updated and enhanced by Robin Howard, Dimitri M. Kullman, David Werring, and Michael Zandi. Neurology: A Clinical Handbook is based on the second edition of Neurology: A Queen Square Textbook. The editors and authors of Neurology: A Queen Square Textbook have not been involved in the development of this Handbook.

      I struggled with several things. First: references. I decided, because one can source most references rapidly on a mobile phone, I would focus only on those references of personal interest. These are largely my own – but with one paper from my late wife Dr Ruth Seifert on khat and another from my father Professor Sir Cyril Astley Clarke on fatal methyl bromide poisoning – from the 1940s; both are in Chapter 19. Well, I thought … this is my book.

      Secondly, with radiology: the internet is full of excellent neuroradiology (e.g. Radiopaedia et al.) that far surpasses printed images. Do please search for such sources – some are mentioned via the additional notes and references on my website:

      https://www.drcharlesclarke.com.

My main experience for some 40 years, like that of Bryan Matthews, has been as a general neurologist in UK district general hospitals, largely the busy battleground of Whipps Cross, but always attached to a major neurology unit, initially St Bartholomew’s and latterly Queen Square. I always found the variety within general neurology more attractive than its emerging specialties. I also broadened my experience by working further afield – during a meningococcal epidemic in Boston, in a leprosy clinic in Mysore, south India and elsewhere in India, Nepal and China, often in remote situations on mountaineering expeditions.

      I thank many people. My parents Cyril and Féo Clarke were distinguished medical researchers, but I suspect they often despaired of me – their practical son who seemed focused on clinical practice and mountaineering,