Clinical Dilemmas in Diabetes. Группа авторов

Optimal Therapy for Cardiovascular Risk in Patients with Diabetes? What Newer Agents Are There for the Treatment for Dyslipidemia in Diabetes? Are Triglycerides an Important Risk Factor for Diabetes? Introduction Dyslipidemia in type 2 diabetes mellitus Treatment of dyslipidemia in type 2 diabetes mellitus Evidence that PSCK 9 is associated with increased CVD risk Evidence linking hypertriglyceridemia to CVD risk in diabetes mellitus Evidence that treating hypertriglyceridemia will decrease CVD risk in DM Discussion References 17 New Agents for Treatment of Dyslipidemia Introduction PCSK9 and regulation of LDL‐Cholesterol levels PCSK9 inhibitors: Efficacy and safety PCSK9 inhibitors: Cardiovascular outcome trails PCSK9 inhibitor use in patients with diabetes PCSK9 inhibitors: Clinical use and future perspectives Other novel lipid‐lowering therapies Conclusions References 18 The Role of Bariatric Surgery in Obese Patients with Diabetes: Primary or Rescue Therapy? Introduction Possible Mechanisms by Which Bariatric Surgery Improves T2DM Role of Bariatric Surgery in T2DM: First‐line Therapy or Rescue Therapy When Medical Options Fail? Role of Weight Loss Surgery in the Treatment of Patients with T2DM and BMI < 35 kg/m² New Techniques that can be an Option in the Future References 19 Treatment Strategies in Patients with Diabetes Mellitus and Ischemic Heart Disease Introduction Role of medical therapy and glucose control Coronary revascularization Conclusions References

      9  PART IV: Management of Disease Complications 20 Diabetes Management in Patients with Critical and Non‐Critical Illness Introduction Mechanisms Mediating Adverse Effects of Hyperglycemia During Critical Illness Large Intervention Studies General Findings (Tables 20.1 and 20.2) Role of Hypoglycemia in Interpretation of Study Results (Table 20.3) Methodology for Glucose Testing The Role of Nutritional Support in Results of Trials Conclusions Acknowledgments References 21 Diagnosis and Management of Ophthalmic Complications of Diabetes Introduction Risk Factors for Diabetic Retinopathy Screening Prevention Ocular Complications Treatment of Diabetic Retinopathy Retinal Vein Occlusion Neovascular Glaucoma Diabetic Macular Edema Treatment of DME Cornea Cataract Orbital Disease References 22 Upper Gastrointestinal Manifestations of Diabetes Introduction Epidemiology Mechanisms and pathophysiology underpinning upper gastrointestinal symptoms in diabetes mellitus Upper gastrointestinal manifestations associated with diabetes Management of gastroparesis and dyspepsia Conclusion References

      10  Index

      11  End User License Agreement

      List of Tables

      1 Chapter 1TABLE 1.1 The sensitivity of various indices of glycemia used to diagnose ty...TABLE 1.2 The sensitivity of various