Прочая образовательная литература
Различные книги в жанре Прочая образовательная литератураDrug Testing In Vitro
Here, expert scientists from industry and academia share their knowledge on the assembly of functional human tissues in vitro and how to design drug screenings predictive of human exposure. In so doing, they combine the latest technological developments with strategic outlooks, such as novel cell and tissue systems for drug screening and testing, as well as emerging in vitro culture technologies. Equally importantly, the book does not shy away from regulatory acceptance and ethical issues.
Lipid Rafts and Caveolae
This keenly awaited first overview of the field represents a complete guide to the structure and function of the most important mammalian cell membrane organelles. Filling a huge gap in the primary literature, this book is the first to cover the subject in detail. Following an introduction by Kai Simons, the discoverer of lipid rafts and the most prominent scientist in the field, chapters include: Historical background Distinct structures and functions Structural basis Signaling Viral entry and virion budding Cholesterol transport Caveolins Lipid shells Cell polarity and intracellular trafficking Cancer cells Of prime importance to molecular and cell biologists, biochemists, membrane scientists, cancer researchers, and virologists.
Handbook of Photosensory Receptors
This first complete resource on photosensory receptors from bacteria, plants and animals compiles the data on all known classes of photoreceptors, creating a must-have reference for students and researchers for many years to come. Among the editors are the current and a former president of the American Society for Photobiology.
RNA Interference in Practice
This hands-on guide to RNA interference brings the power of targeted gene silencing to any laboratory with the basic equipment for handling nucleic acids. In easy-to-follow, step-by-step protocols you will learn * how RNAi works in worms, flies and mammals, * how to design the most efficient RNAi constructs, * how to achieve transient, stable and conditional RNAi in cell cultures, * how to determine the efficiency of an RNAi experiment, * and how to use RNAi for gene therapy. All the protocols have been thoroughly tested in the author's own laboratory, and she provides examples of successful experiments and troubleshooting hints to help in establishing your own successful RNAi experiments. Also includes a list of suppliers for RNAi reagents and equipment as well as a glossary of terms.
Mechanisms in Transcriptional Regulation
Mechanisms in Transcriptional Regulation provides a concise discussion of the fundamental concepts in transcription and its regulation. Covers RNA polymerases, transcriptional machinery, mechanisms of transcriptional activation, the histone code hypothesis, the epigenetic control of transcription, and combinatorial control in signaling and development Features over 80 figures available to download online Chapters include comprehensive reading lists, boxes highlighting theoretical concepts and experimental methods and problems designed to build and test understanding
Principles of Cell Proliferation
Controlled expansion of cell populations is a fundamental feature of living organisms, being a finely-tuned balance between cell proliferation and cell death. This book aims to explain the molecular mechanisms that lie behind the multiplication and survival of eukaryotic cells. This encompasses both the normal regulation of cell populations in development or physiological adaptation and pathological mechanisms of cell cycle control in cancer. Principles of Cell Proliferation progressively introduces the function of growth factors, receptors, signal transduction pathways, gene expression and the conserved mechanisms of the cell cycle engine. This provides a context for understanding the mechanistic consequences of the genetic alterations in oncogenes and tumour suppresser genes which underlie tumour formation. The book should satisfy advanced level courses in Cell Proliferation, Cell Cycle Control and Cancer Biology for biologists, biochemists and medical students. The book comes at a time when the underlying molecular mechanisms of cancer are beginning to be unravelled. Ideal for advanced level courses in Cell Proliferation, Cell Cycle or Cancer Biology. An accessible account of a subject many students find complex.
Chromatin and Gene Regulation
Written in an informal and accessible style, Chromatin and Gene Regulation enables the reader to understand the science of this rapidly moving field. Chromatin is a fundamental component in the network of controls that regulates gene expression. Many human diseases have been linked to disruption of these control processes by genetic or environmental factors, and unravelling the mechanisms by which they operate is one of the most exciting and rapidly developing areas of modern biology. Chromatin is central both to the rapid changes in gene transcription by which cells respond to changes in their environment and also to the maintenance of gene expression patterns from one cell generation to the next. This book will be an invaluable guide to undergraduate and postgraduate students in the biological sciences and all those with an interest in the medical implications of aberrant gene expression.
Basement Membranesand Cell Movement
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
Submolecular Biology and Cancer
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
Locomotion of Tissue Cells
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.