Прочая образовательная литература
Различные книги в жанре Прочая образовательная литератураViral Therapy of Cancer
In the last decade there has been an explosion of interest in viral therapies for cancer. Viral agents have been developed that are harmless to normal tissues but selectively able to kill cancer cells. These agents have been endowed with additional selectivity and potency through genetic manipulation. Increasingly these viruses are undergoing evaluation in clinical trials, both as single agents and in combination with standard chemotherapy and radiotherapy. This book provides a comprehensive yet succinct overview of the current status of viral therapy of cancer. Chapters coherently present the advances made with individual agents and review the biological and clinical background to a range of viral therapies: structured to proceed from basic science at the bench to the patient’s bedside, they give an up-to-date and realistic evaluation of a therapy’s potential utility for the cancer patient. Presents state of the art knowledge on how viruses can be, and have been, used in novel therapeutic approaches for the treatment of cancer Describes the use of viruses as oncolytic agents, killing cells directly Editors are experts in the field, with experience of both laboratory and clinical research Viral Therapy of Cancer is essential reading for both basic scientists and clinicians with an interest in viral therapy and gene therapy.
Diagnostic Techniques in Genetics
Recent developments within molecular biology and genetic engineering have led to huge advances and changes within the biological sciences especially within the field of human genetics. Diagnostic Techniques in Genetics offers an important overview of how DNA or RNA technology may be applied to a large set of genetic diagnoses. The first part of the book focuses on DNA/RNA applications and includes many of the latest developments in the field combined with routine procedures of genetic diagnoses, for example cloning and sequencing DNA. The DNA applications presented in the first chapter are then each applied to a specific kind of genetic diagnosis and the text concludes with a chapter devoted to population genetics. First published in French by Dunod in 2002, this book is an excellent reference for students taking courses in molecular biology, medicine and medical genetics. It is also a useful introduction for postgraduate students and researchers in the field who require a general overview of genetic diagnoses.
From Genes to Genomes
“… an excellent book… achieves all of its goals with style, clarity and completeness… You can see the power and possibilities of molecular genetics as you read…” –Human Genetics «This volume hits an outstanding balance among readability, coverage, and detail.» –Biochemistry and Molecular Biology Education Rapid advances in a collection of techniques referred to as gene technology, genetic engineering, recombinant DNA technology and gene cloning have pushed molecular biology to the forefront of the biological sciences. This new edition of a concise, well-written textbook introduces key techniques and concepts involved in cloning genes and in studying their expression and variation. The book opens with a brief review of the basic concepts of molecular biology, before moving on to describe the key molecular methods and how they fit together. This ranges from the cloning and study of individual genes to the sequencing of whole genomes, and the analysis of genome-wide information. Finally, the book moves on to consider some of the applications of these techniques, in biotechnology, medicine and agriculture, as well as in research that is causing the current explosion of knowledge across the biological sciences. From Genes to Genomes: Concepts and Applications of DNA Technology, Second Edition includes full two-colour design throughout. Specific changes for the new edition include: Strengthening of gene to genome theme Updating and reinforcing of material on proteomics, gene therapy and stem cells More eukaryotic/mammalian examples and less focus on bacteria This textbook is must-have for all undergraduates studying intermediate molecular genetics within the biological and biomedical sciences. It is also of interest for researchers and all those needing to update their knowledge of this rapidly moving field.
Immunogenomics and Human Disease
This book provides an overview of key conceptual and molecular technologies being deployed in immunogenomics, followed by detailed evaluations of the impact of genomics and systems biology on important areas such as cancer immunology, autoimmunity, allergy and the response to infection.
Statistical Data Analysis Explained
Few books on statistical data analysis in the natural sciences are written at a level that a non-statistician will easily understand. This is a book written in colloquial language, avoiding mathematical formulae as much as possible, trying to explain statistical methods using examples and graphics instead. To use the book efficiently, readers should have some computer experience. The book starts with the simplest of statistical concepts and carries readers forward to a deeper and more extensive understanding of the use of statistics in environmental sciences. The book concerns the application of statistical and other computer methods to the management, analysis and display of spatial data. These data are characterised by including locations (geographic coordinates), which leads to the necessity of using maps to display the data and the results of the statistical methods. Although the book uses examples from applied geochemistry, and a large geochemical survey in particular, the principles and ideas equally well apply to other natural sciences, e.g., environmental sciences, pedology, hydrology, geography, forestry, ecology, and health sciences/epidemiology. The book is unique because it supplies direct access to software solutions (based on R, the Open Source version of the S-language for statistics) for applied environmental statistics. For all graphics and tables presented in the book, the R-scripts are provided in the form of executable R-scripts. In addition, a graphical user interface for R, called DAS+R, was developed for convenient, fast and interactive data analysis. Statistical Data Analysis Explained: Applied Environmental Statistics with R provides, on an accompanying website, the software to undertake all the procedures discussed, and the data employed for their description in the book.
Testing for EMC Compliance
The Keep It Simple (KISS) philosophy is the primary focus of this book. It is written in very simple language with minimal math, as a compilation of helpful EMI troubleshooting hints. Its light-hearted tone is at odds with the extreme seriousness of most engineering reference works that become boring after a few pages. This text tells engineers what to do and how to do it. Only a basic knowledge of math, electronics, and a basic understanding of EMI/EMC are necessary to understand the concepts and circuits described. Once EMC troubleshooting is demystified, readers learn there are quick and simple techniques to solve complicated problems a key aspect of this book. Simple and inexpensive methods to resolve EMI issues are discussed to help generate unique ideas and methods for developing additional diagnostic tools and measurement procedures. An appendix on how to build probes is included. It can be a fun activity, even humorous at times with bizarre techniques (i.e., the sticky finger probe).
Practical Gamma-ray Spectroscopy
The Second Edition of Practical Gamma-Ray Spectrometry has been completely revised and updated, providing comprehensive coverage of the whole gamma-ray detection and spectrum analysis processes. Drawn on many years of teaching experience to produce this uniquely practical volume, issues discussed include the origin of gamma-rays and the issue of quality assurance in gamma-ray spectrometry. This new edition also covers the analysis of decommissioned nuclear plants, computer modelling systems for calibration, uncertainty measurements in QA, and many more topics.
Genetic Algorithms in Electromagnetics
A thorough and insightful introduction to using genetic algorithms to optimize electromagnetic systems Genetic Algorithms in Electromagnetics focuses on optimizing the objective function when a computer algorithm, analytical model, or experimental result describes the performance of an electromagnetic system. It offers expert guidance to optimizing electromagnetic systems using genetic algorithms (GA), which have proven to be tenacious in finding optimal results where traditional techniques fail. Genetic Algorithms in Electromagnetics begins with an introduction to optimization and several commonly used numerical optimization routines, and goes on to feature: Introductions to GA in both binary and continuous variable forms, complete with examples of MATLAB(r) commands Two step-by-step examples of optimizing antenna arrays as well as a comprehensive overview of applications of GA to antenna array design problems Coverage of GA as an adaptive algorithm, including adaptive and smart arrays as well as adaptive reflectors and crossed dipoles Explanations of the optimization of several different wire antennas, starting with the famous «crooked monopole» How to optimize horn, reflector, and microstrip patch antennas, which require significantly more computing power than wire antennas Coverage of GA optimization of scattering, including scattering from frequency selective surfaces and electromagnetic band gap materials Ideas on operator and parameter selection for a GA Detailed explanations of particle swarm optimization and multiple objective optimization An appendix of MATLAB code for experimentation
Ecology of Coastal Waters
Ecology of Coastal Waters with Implications for Management, Second Edition is the most up-to-date book available on coastal marine ecosystems. Students will easily relate to the content of the book as subjects are divided by the environment and scientific principles are applied to steps in the management and the decision making process. This is the ideal text for undergraduate and graduate life science students as well as for practicing professionals.
Stream and Watershed Restoration
With $2 billion spent annually on stream restoration worldwide, there is a pressing need for guidance in this area, but until now, there was no comprehensive text on the subject. Filling that void, this unique text covers both new and existing information following a stepwise approach on theory, planning, implementation, and evaluation methods for the restoration of stream habitats. Comprehensively illustrated with case studies from around the world, Stream and Watershed Restoration provides a systematic approach to restoration programs suitable for graduate and upper-level undergraduate courses on stream or watershed restoration or as a reference for restoration practitioners and fisheries scientists. Part of the Advancing River Restoration and Management Series. Additional resources for this book can be found at: www.wiley.com/go/roni/streamrestoration.