Evidence Based Pediatrics and Child Health is a ground-breaking new text on pediatrics and child care management, using evidence based approach. It covers all the major childhood conditions and contains the features of both a handbook and a reference text. Each chapter combines both advice on management and how best to practice evidence based medicine with reviews of all the available evidence in a specific area. The goal of the book is to help pediatricians and others who care for children to provide the best possible care by combining the best, most current evidence with special circumstances of each individual patient.
Evidence-based Pediatric Infectious Diseases is a practical guide to the diagnosis and management of childhood infections in clinical practice. Renowned Clinical Professor of Pediatric Infectious Diseases, David Isaacs, and an expert consultant editor team, bring you the first book to critically look at the evidence for decision making in pediatric infections. Based around illustrative case studies, each chapter presents and analyzes current evidence on the management of different pediatric infections and provides firm treatment recommendations based on evidence of: • efficacy and safety • antibiotic resistance • cost • adverse effects • ethical considerations. Clear summaries and specific guidance allow you to assess the evidence for yourself and make rapid but informed management decisions based on the strength of evidence available. Antibiotic doses are presented clearly and simply, enabling you to select appropriate treatment at a glance. This book uses a case-based approach that focuses on the most common disease areas affecting children in industrialized countries, developing countries, travelers and refugees. It is an up-to-date, relevant and widely applicable text that carefully examines the evidence for antibiotics and other interventions whilst encouraging a conservative and responsible approach to antibiotic use. Evidence-based Pediatric Infectious Diseases is an indispensable resource for any practitioner who strives to provide the best evidence-based care for childhood infections.
The aim of this book has always been to give guidance on the diagnosis and treatment of ocular motility disorders based on clinical experience, as opposed to a comprehensive treatise on the subject drawn from the primary literature. The Third Edition sees a new team of authors who have kept very much to this priniciple in their nevertheless thorough revision of the book. Whilst there are no new chapters as such, the immediate impact of the revision is in the improved page layout with increased use of diagrams and flowcharts. There are new sections on feigned visual loss in adults and children, the management of residual defects and the section on botulinum toxin treatment in chapter 8 will be re-written to take account of the great advances in this form of treatment.
TNM Classification of Malignant Tumours, 7th Edition provides the latest, internationally agreed-upon standards to describe and categorize cancer stages and progression. Published in affiliation with the International Union Against Cancer (UICC), this authoritative guide contains important updated organ-specific classifications that oncologists and other professionals who manage patients with cancer need to accurately classify tumours for staging, prognosis and treatment. The major alterations addressed in the 7th Edition concern carcinomas of the oesophagus and the gastroesophageal junction, stomach, lung, appendix, biliary tract, skin, and prostate. In addition, there are several entirely new classifications: gastrointestinal carcinoids (neuroendocrine tumours) gastrointestinal stromal tumour upper aerodigestive mucosal melanoma Merkel cell carcinoma uterine sarcomas intrahepatic cholangiocarcinoma adrenal cortical carcinoma. A new approach has also been adopted to separate anatomical stage groupings from prognostic groupings in which other prognostic factors are added to T, N, and M categories. These new prognostic groupings, as well as the traditional anatomical groupings, are presented for oesophageal and prostate carcinomas. Visit www.wileyanduicc.com for more information about the International Journal of Cancer and our other UICC book titles
The accessible guide to the principles behind new, more targeted drug treatments for cancer Written for anyone who encounters cancer patients, cancer data or cancer terminology, but have no more than a passing knowledge of cell biology. A Beginner's Guide to Targeted Cancer Treatments provides an understanding of how cancer works and the many new treatments available. Using over 100 original illustrations, this accessible handbook covers the biology and mechanisms behind a huge range of targeted drug treatments, including many new immunotherapies. Dr Vickers translates a complex and often overwhelming topic into something digestible and easily understood. She also explains what cancer is, how it behaves and how our understanding of cancer has changed in recent years. Each chapter takes the reader through how new cancer drugs work and their benefits and limitations. With the help of this book, readers will be able to better understand more complex, in-depth articles in journals and books and develop their knowledge. This vital resource: Offers the latest insights into cancer biology Provides a broad understanding of how targeted cancer treatments work Describes many of the new immunotherapy approaches to cancer treatment, such as checkpoint inhibitors and CAR-modified T cells Helps readers feel confident discussing treatment options with colleagues and patients Provides an overview of which treatments are relevant to each of the most common solid tumours and haematological cancers, and the rationale behind them Demystifies the jargon – terms such as the EMT, cancer stem cells, monoclonal antibodies, kinase inhibitors, angiogenesis inhibitors etc. Explains the resistance mechanisms to many new treatments, including issues such as the way cancer cells diversify and evolve and the complex environment in which they live
This handbook is designed to help jobbing histopathologists jog their memory and get through more workload in any working day. Rapid access is facilitated by a bullet-point, tabular and diagrammatic style, as well as by handy anatomical diagrams, guidance on the ‘Cut-Up’ with emphasis on core ‘datasets’ and by a special index for frozen section advice, grading systems and scoring systems. The book provides, where useful, differential diagnosis lists and presents diagnostically helpful molecular and immunohistochemical findings. Information is kept up-to-date on a dedicated website www.pathbook.com. The Diagnostic Criteria Handbook in Histopathology is not designed to be an “exam cram” and neither will it serve as a basic text for beginners. Trainees, however, will still benefit from the sheer breadth of topics covered in this one small volume: from lab management and lab methods, to autopsy practice, cytology and all sub-specialties in surgical pathology. A chapter on exam technique and mnemonics makes the book also an essential companion for those revising for professional exams. So why clutter your precious desk space with multiple sets of heavy two-volume reference works? Give this handy Vade Mecum a place next to your microscope and see how much time you could save!
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
This international symposium focuses on the contributions that biomedical research is making to the provision of proper health care for the increasing numbers of elderly people in all countries, developed and developing. Recent, encouraging developments in the areas of malignancy, dementia, osteoporosis, and cardiovascular disease are emphasized. Also addresses new ways of planning health care and social support systems for the elderly.
Cancer Vaccines and Tumor Immunity offers a review of the basic scientific discoveries that have moved forward into clinical trials. Presented in the context of real-world human research and experimentation, these major scientific advances demonstrate how our understanding of immune activation, T-regulatory cells, and autoimmunity will impact cancer vaccine design. The authors also explain how vaccination in the context of bone marrow transplantation will open new avenues for clinical study in the future.
Introduction to Occupational Health in Public Health Practice Bernard J. Healey and Kenneth T. Walker Introduction to Occupational Health in Public Health Practice Introduction to Occupational Health in Public Health Practice uses concepts of prevention, epidemiology, toxicology, disparities, preparedness, disease management, and health promotion to explain the underlying causes of occupational illness and injury and to provide a methodology to develop cost-effective programs that prevent injury and keep workers safe. Students, health educators, employers, and other health care professionals will find that this essential resource provides them with the necessary skills to develop, implement, and evaluate occupational health programs and forge important links between public health and worker safety. Praise for Introduction to Occupational Health in Public Health Practice «Successful evidence-based health promotion and disease prevention efforts recognize that health choices and outcomes of individuals and communities are profoundly affected by their respective social and physical environments. This book is a great tool to identify opportunities and strategies to integrate and leverage efforts for the individual, family, workplace, and broader community.» —Robert S. Zimmerman, MPH, president of Public Health Matters LLC, former Secretary of Health, Pennsylvania «A timely and crucial book for all health care professionals.» —Mahmoud H. Fahmy, PhD, Professor of Education, Emeritus, Wilkes University