Медицина
Различные книги в жанре МедицинаCoercive Treatment in Psychiatry. Clinical, legal and ethical aspects
Coercion is one of the most fascinating and controversial subjects in psychiatry. It is a highly sensitive, and hotly debated topic in which clinical practice, ethics, the law and public policy converge. This book considers coercion within the healing and ethical framework of therapeutic relationships and partnerships at all levels, and addresses the universal problem of how to balance safety versus autonomy when dealing with psychiatric treatment. Coercive Treatment in Psychiatry is a much needed contribution to the literature. The first three sections deal with the conceptual and clinical aspects of coercive treatment, the legal aspects and the ethical aspects of coercive treatment. In detail, these sections cover a broad spectrum of issues: coercion in institutions and in the community, coercive treatment and stigma, the definition of best practice standards for coercive treatment, de-escalation of risk situations, recent developments in mental health legislation, mental health care and patients' rights, cross-cultural perspectives on coercive treatment, historical injustice in psychiatry, and paternalism in mental health. The fourth section features users' views on coercive treatment: giving voice to an often-unheeded population. Finally, the book addresses the original topic of coercion and undue influence in decisions to participate in psychiatric research. This book presents the first comprehensive review of the issue of coercion in psychiatry. With chapters written by the leading experts in the field, many of whom are renowned as clear thinkers and experienced clinicians, it may be seen as a starting point for international discussions and initiatives in this field aiming to minimize coercion. Highly Commended in the Psychiatry section of the 2012 BMA Book Awards.
Pharmacogenomics of Human Drug Transporters. Clinical Impacts
Sets the foundation for safer, more effective drug therapies With this book as their guide, readers will discover how to apply our current understanding of the pharmacogenomics of drug transporters to advance their own drug discovery and development efforts. In particular, the book explains how new findings in the field now enable researchers to more accurately predict drug interactions and adverse drug reactions. Moreover, it sets the foundation for the development of drug therapies that are tailored to an individual patient's genetics. Pharmacogenomics of Human Drug Transporters serves as a comprehensive guide to how transporters regulate the absorption, distribution, and elimination of drugs in the body as well as how an individual's genome affects those processes. The book's eighteen chapters have been authored by a team of leading pioneers in the field. Based on their own laboratory and clinical experience as well as a thorough review of the literature, these authors explore all facets of drug transporter pharmacogenomics, including: Individual drug transporters and transporter families and their clinical significance Principles of altered drug transport in drug–drug interactions, pharmacotherapy, and personalized medicine Emerging new technologies for rapid detection of genetic polymorphisms Clinical aspects of genetic polymorphisms in major drug transporter genes Future research directions of drug transporter pharmacogenomics and the prospect of individualized medicine Pharmacogenomics of Human Drug Transporters opens the door to new drug discovery and development breakthroughs leading to safer and more effective customized drug therapies.The book is recommended for pharmaceutical scientists, biochemists, pharmacologists, clinicians, and genetics and genomics researchers.
Handbook of Pediatric Hematology and Oncology. Children's Hospital and Research Center Oakland
This new edition of Handbook of Pediatric Hematology and Oncology: Children's Hospital & Research Center Oakland features practical guidance on how to handle common inpatient and outpatient challenges seen in pediatric hematology and oncology. Designed as a rapid reference to the latest diagnostic and therapeutic protocols, the text is short and didactic and supplemented with practical algorithms and case studies throughout. Completely revised and updated, there are brand-new chapters on subjects including bone marrow transplantation, pain management and palliative care. Comprehensive, yet concise, the handbook presents essential guidelines on the diagnosis and management of the most common pediatric blood disorders and malignancies, in addition to chemotherapeutic drug information and transfusion protocols. Designed for medical students, residents, and fellows, this user-friendly portable reference is also the perfect companion on the ward for pediatric hematology and oncology nurses.
Predictive Approaches in Drug Discovery and Development. Biomarkers and In Vitro / In Vivo Correlations
Practical Utility of Biomarkers in Drug Discovery and Development covers all aspects of biomarker research applied to drug discovery and development and contains state-of-the-art appraisals on the practical utility of genomic, biochemical, and protein biomarkers. Case histories and lessons from successful and unsuccessful applications of biomarkers are included along with key chapters on GLP validation, safety biomarkers and proteomics biomarkers. Regulatory agency perspectives and initiatives both in the US and internationally are also discussed.
Religion and Psychiatry. Beyond Boundaries
Religion (and spirituality) is very much alive and shapes the cultural values and aspirations of psychiatrist and patient alike, as does the choice of not identifying with a particular faith. Patients bring their beliefs and convictions into the doctor-patient relationship. The challenge for mental health professionals, whatever their own world view, is to develop and refine their vocabularies such that they truly understand what is communicated to them by their patients. Religion and Psychiatry provides psychiatrists with a framework for this understanding and highlights the importance of religion and spirituality in mental well-being. This book aims to inform and explain, as well as to be thought provoking and even controversial. Patiently and thoroughly, the authors consider why and how, when and where religion (and spirituality) are at stake in the life of psychiatric patients. The interface between psychiatry and religion is explored at different levels, varying from daily clinical practice to conceptual fieldwork. The book covers phenomenology, epidemiology, research data, explanatory models and theories. It also reviews the development of DSM V and its awareness of the importance of religion and spirituality in mental health. What can religious traditions learn from each other to assist the patient? Religion and Psychiatry discusses this, as well as the neurological basis of religious experiences. It describes training programmes that successfully incorporate aspects of religion and demonstrates how different religious and spiritual traditions can be brought together to improve psychiatric training and daily practice. Describes the relationship of the main world religions with psychiatry Considers training, policy and service delivery Provides powerful support for more effective partnerships between psychiatry and religion in day to day clinical care This is the first time that so many psychiatrists, psychologists and theologians from all parts of the world and from so many different religious and spiritual backgrounds have worked together to produce a book like this one. In that sense, it truly is a World Psychiatric Association publication. Religion and Psychiatry is recommended reading for residents in psychiatry, postgraduates in theology, psychology and psychology of religion, researchers in psychiatric epidemiology and trans-cultural psychiatry, as well as professionals in theology, psychiatry and psychology of religion
Von Willebrand Disease. Basic and Clinical Aspects
Von Willebrand Disease: Basic and Clinical Aspects provides an insight into all aspects of the condition. Since its discovery, von Willebrand disease has been extensively studied and the causative factor deficiency, the understanding of the condition and its treatment has greatly improved. This book summarizes recent research and will help to optimize the management of patients with von Willebrand disease. This valuable book describes the important and complex role of von Willebrand factor in hemostasis and thrombosis. In addition to the current understanding of its molecular biology, this book gives particular focus to the association between genetic variants of von Willebrand factor and different von Willebrand disease phenotypes. It also reviews the important area of the obstetric and gynecological manifestations of von Willebrand disease, as well as the treatment of acute bleeding. Written by an international team of contributors it describes the progress in, and difficulties of diagnosing phenotypes and genotypes. Molecular diagnosis of type 1, type 2 and its subgroups, and type 3 von Willebrand disease are presented as well as discussion of the potential future role of gene therapy. Von Willebrand Disease: Basic and Clinical Aspects is a valuable resource for hematologists in practice and in training, and specialists in thrombosis and hemostasis.
Reverse Genetics of RNA Viruses. Applications and Perspectives
Reverse genetics, the genetic manipulation of RNA viruses to create a wild-type or modified virus, has led to important advances in our understanding of viral gene function and interaction with host cells. Since many severe viral human and animal pathogens are RNA viruses, including those responsible for polio, measles, rotaviral diarrhoea and influenza infections, it is also an extremely powerful technique with important potential application for the prevention and control of a range of human and animal viral diseases. Reverse Genetics of RNA Viruses provides a comprehensive account of the very latest developments in reverse genetics of RNA viruses through a wide range of applications within each of the core virus groups including; positive sense, negative sense and double stranded RNA viruses. Written by a team of international experts in the field, it provides a unique insight into how the field has developed, what problems are being addressed now and where applications may lead in the future. It will prove invaluable to bioscience, medical and veterinary students, those starting research in this area as well as other researchers and teachers needing to update their knowledge of this fast-moving field. An authoritative, comprehensive overview of reverse genetics in RNA Viruses. Includes numerous examples of cutting- edge applications of reverse genetics within each of the RNA viral groups. Written by a team of international experts, including some of the leading researchers in the field.
Financial Management of Health Care Organizations. An Introduction to Fundamental Tools, Concepts and Applications
This new Fourth Edition of Financial Management of Health Care Organizations, offers an introduction to the most-used tools and techniques of health care financial management, including health care accounting and financial statements; managing cash, billings and collections; making major capital investments; determining cost and using cost information in decision-making; budgeting and performance measurement; and pricing. New to this edition: The Perspectives sections and the glossary have been updated. The book features a cutting-edge view of the health care landscape in 2013 and beyond after passage and pending implementation of the Affordable Care Act. Areas of expanded content include revised examples of financial statements for both private non-profit hospitals and investor-owned hospital management companies, changes in bad debt and charity care, the role of financial statements, the discount rate or cost of capital, lease financing section, use of cost information, budgeting, cost centers, and current forms of reimbursement Content new to this edition includes valuation of accounts receivable and the «waterfall» effect of cash collections, differences between Posting-Date and Service-Date reporting methodologies, calculation of effective annual interest rate, application of time value of money in perspectives, and Activity-Based Costing from the perspective of labor, supplies, and equipment.
The New Prescriber. An Integrated Approach to Medical and Non-medical Prescribing
The New Prescriber is a comprehensive, accessible textbook that provides essential coverage of the three core components for prescribing: the client/patient, the evidence, and the pharmacology. Divided into three sections, this text first looks at the consultation with the patient, and outlines legal, professional and ethical frameworks which guide medical and non-medical prescribing. The second section is devoted to evidence-based practice, highlighting key skills essential to all clinicians. This section encourages the student to identify why evidence-based practice should underpin prescribing decisions. The third and final section is concerned with pharmacology. The student is introduced to basic concepts of pharmacodynamics and pharmacokinetics, adverse drug reactions and variability of response. The importance of these pharmacological principles is highlighted throughout the subsequent discussion of drug groups affecting major body systems. Key features: Pulls together all key elements of prescribing using an integrated approach ‘Stop and Think' boxes and practice application activities provided throughout, enabling the reader to link theory to practice Key terms and glossary provided This text is invaluable for all nursing, health and medical students taking courses in prescribing and pharmacology.
Queenan's Management of High-Risk Pregnancy. An Evidence-Based Approach
Changing demographics and evolving technology continuously affect maternal-fetal medicine Increasing maternal age and weight during pregnancy, higher rates of pregnancies conceived by artificial reproductive technologies and growing numbers of cesarean deliveries have led to a rise in the incidence of complicated pregnancies. The options have also increased for monitoring maternal and fetal health throughout a pregnancy, and identifying and managing risk earlier. For the maternal-fetal physician, constant vigilance throughout a pregnancy remains essential. But continuous change makes this an increasing challenge. Queenan’s Management of High-Risk Pregnancy covers the full spectrum of perinatal care. It guides you through the tough and complex decisions needed to protect the health of both your fetal and the maternal patients. New material in the 6th edition covers contemporary issues such as: Iron-deficient anemia Malaria Pregnancy in the disabled woman Placenta accreta Induction of labor Operative vaginal delivery Patient safety in labor and delivery The stellar cast of expert authors provide evidence, algorithms, case studies and potential outcome measures to ensure that Queenan's Management of High-Risk Pregnancy continues to set the bar for maternal-fetal practice. Titles of Related Interest Stillbirth Edited by Catherine Y. Spong ISBN 978-1-4443-3706-8 The Placenta: From Development to Disease Edited by Helen Kay, D. Michael Nelson and Yuping Wang ISBN 978-1-4443-3366-4 Pregnancy in the Obese Woman: Clinical Management Edited by Deborah E. Conway ISBN 978-1-4051-9648-2