Most drugs are analogue drugs. There are no general rules how a new drug can be discovered, nevertheless, there are some observations which help to find a new drug, and also an individual story of a drug discovery can initiate and help new discoveries. Volume III is a continuation of the successful book series with new examples of established and recently introduced drugs. The major part of the book is written by key inventors either as a case study or a study of an analogue class. With its wide range across a variety of therapeutic fields and chemical classes, this is of interest to virtually every researcher in drug discovery and pharmaceutical chemistry, and – together with the previous volumes – constitutes the first systematic approach to drug analogue development.
Esophageal Cancer and Barrett’s Esophagus, 3E, focuses on these two common and key conditions that affect the esophagus, providing expert guidance to their pathogenesis, cause, prevention, diagnosis and clinical management. Top international names in the field examine each of the many issues involved, using the very latest evidence-based research, and clear, didactic advice allows the reader to understand the best methods of diagnosis and clinical management of each condition – whether early or late stage. Well-illustrated and fully revised to include the latest in ACG/ASG/UEGW guidelines, it is the perfect consultation tool for gastroenterologists and oncologists managing patients with cancer of the esophagus. It is also ideal for teaching residents and fellows optimum patient management, and for identifying areas requiring future research.
Clinical Problems in Oncology: A Practical Guide to Management is an easy-to-use, compact reference with essential, practical information on managing oncological emergencies, as well as the side effects and complications of cancer and its treatment. Because patient responses can vary widely, depending on the type of treatment prescribed, this resource offers medical professionals the specific information they need to improve the evaluation and treatment of cancer patients at the point of care. The compact format includes a wide range of clinical information, from the dose of drugs that would typically be used, through guidance on the practical procedures that are frequently used to treat oncology patients. Some of the book’s highlights include: • Toxicity grading and management, including at-a-glance summaries of the most common toxicities associated with chemotherapy • Prescribing guidelines, including how to write up electrolyte replacement properly • Information on specialised oncology procedures (such as SIR spheres), and how to manage complications • Types of vascular access lines and how to check their position, access them and troubleshoot problems With an expert team of writers who have contributed materials in their areas of expertise, Clinical Problems in Oncology is an ideal reference for oncologists in training, oncologists in non-training positions, oncology registrars and general practitioners.
Clinical Reasoning in Small Animal Practice presents a revolutionary approach to solving clinical problems. As a veterinarian, especially as a student or new graduate, a ten minute consultation in a busy small animal practice can be a daunting task. By guiding you to think pathophysiologically, this book will help solve clinical problems as efficiently as possible. The authors set out a structured approach with easy to remember rules which can be applied to most clinical signs small animals present with. This reduces the need to remember long lists of differentials and avoids the potential of getting trapped by a perceived obvious diagnosis. The book will help to unlock your potential to solve clinical problems. It also provides a logical rationale for choosing diagnostic tests or treatments which can be clearly communicated to the owner. Written by internationally renowned clinicians and educators in clinical reasoning, key features of the book include: An easy to remember and logical approach to solving a wide range of clinical problems encountered in small animal medicine and neurology An invaluable resource for every level of learner, from student to experienced practitioner Flowcharts and key step markers throughout help illustrate the decision making process Clinical inductive reasoning offers you the ability to solve cases more efficiently, resulting in better treatment and care for pets and happier owners. Clinical Reasoning in Small Animal Practice will help turn a terrifying case into a manageable one!
The Nurse Practitioner’s Guide to Nutrition is a comprehensive clinical resource for nurse practitioners working in a variety of clinical care settings. Emphasizing practical nutrition information, this accessible guide provides guidance on incorporating nutrition history questions and counselling techniques into routine care across all clinical settings. The book begins by discussing fundamental concepts in nutrition assessment, giving readers a solid framework from which to approach subsequent chapters. Section Two focuses on nutrition from a lifespan perspective, organizing information by the issues most pertinent to patients at different stages of life. Section Three presents nutrition counselling across clinical care settings ranging from cardiology, endocrinology, oncology, and gastroenterology to caring for the obese patient. Each chapter includes essential information distilled in quick-access tabular format and clinical scenarios that apply key concepts discussed to real-world examples. Ideal for both in-training and qualified advanced practice nurses, The Nurse Practitioner’s Guide to Nutrition is an essential tool for assessing, managing, and treating nutrition-related conditions, as well as promoting nutritional health for all patients. This activity has been approved for 35 nursing continuing education contact hours through the Temple University College of Health Professions and Social Work Department of Nursing Provider Unit, an approved provider of continuing nursing education by the Pennsylvania State Nurses Association, itself an accredited approver by the American Nurses Credentialing Center’s Commission on Accreditation. For e-book users: CNE materials are available for download after purchase. This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from Google Play or the MedHand Store.
Inflammatory Bowel Diseases: A Clinician’s Guide provides practical guidance for the diagnosis and management of those suspected or known to have one of the forms of these complex diseases. It is perfect both for gastroenterology trainees learning to care for these patients and the experienced physician as a concise and practical resource for day to day use. Written by the experts, Inflammatory Bowel Diseases: A Clinician’s Guide is an essential tool for all gastroenterologists managing patients with inflammatory bowel disease.
Bladder Cancer: Diagnosis and Clinical Management is a 100% clinically-focused guide to bladder cancer, providing practical, modern and evidence-based guidance to the latest in diagnosis and management of the condition. It differs from other books in its complete clinical focus as opposed to a heavy analysis of pathogenesis or basic science. As a result, practicing urologists and oncologists in the clinical setting will find it an essential resource to consult. In addition to the latest in diagnostic tools and imaging methods, core focus is on the management of each form of cancer at its various stages with up to date genomic data and targeted therapies. Both drug therapies and the range of surgical options are covered, ensuring that this is the perfect tool for clinicians to consult when considering which type of management program is appropriate for each individual patient. A key addition is the final section dedicated to optimizing health care delivery, featuring chapters on highly topical issues such as quality of life, patient advocacy and surgical education. Full color throughout, and packed with excellent images, each chapter contains concise and didactic practical tips and tricks to enrich the reading experience, in addition to management algorithms and the very latest guidelines from the ASCO, AUA, ESMO and EAU concerning clinical management of bladder cancer.
The ABC of Sports and Exercise Medicine provides general practitioners with a comprehensive overview of the field of sports medicine. This highly illustrated and thoroughly revised and updated new edition: • Reflects new developments and current practice • Includes new chapters on medical care at sporting events, environmental factors of sports and exercise, benefits of exercise in health and disease, nutrition and ergogenic supplements, and the use of drugs in sport • Covers the benefits of exercise among special populations such as the disabled, obese, pregnant, children and the elderly Covering the latest topics and including case studies of common sports and exercise medicine conditions, the ABC of Sports and Exercise Medicine is an essential practical guide for general practitioners, family physicians, junior doctors, medical students, physiotherapists, and all health professionals dealing with the treatment and prevention of sports-related injuries.
Do you have patients referred to you suffering from NAFLD? Are you looking for an expert guide to the latest in clinical management? If so, this is the book for you, providing an expert and comprehensive analysis of NAFLD: what it is, why it happens, who is likely to suffer from it, and how to decide on the best management options for your patients. This book focuses clearly on providing first-rate clinical guidance as to the assessment, diagnosis and treatment of patients in the clinical setting, based wherever possible on the latest evidence and scientific understanding of disease mechanisms. With each chapter fully revised and updated with the very latest in AASLD, EASL and Asia-Pacific guidelines, this second edition provides: Four brand new chapters, including “NAFLD and cardiovascular risk factors” and “Non-invasive methods to determine severity of NAFLD/ NASH” A clear overview on the causative mechanisms of NAFLD Self-assessment via key points and multiple-choice questions throughout The very latest in clinical drug trials Analysis of NAFLD in relation to obesity, diabetes, high cholesterol and liver cancer A consideration of NAFLD importance in Asia (particularly including Japan and China) and South America, as well as Europe and North America NAFLD is a serious condition that is increasing in prevalence globally from year to year. Non-Alcoholic Fatty Liver Disease: A Practical Guide, is essential reading for all hepatologists and health professionals managing patients who have this condition.
Second edition of an established text on common procedures for the identification and processing of evidence at scenes of crime Includes chapters on quality assurance and credibility of practices and processes issues surrounding major and complex crime Forensic handling of mass fatalities Crime scene reconstruction and impact on evidence recovery processes