Transporters and Drug-Metabolizing Enzymes in Drug Toxicity. Albert P. Li
Медицина.
Transporters and Drug-Metabolizing Enzymes in Drug Toxicity
Год выпуска 0
isbn 9781119170990
Автор произведения Albert P. Li
Жанр Медицина
Издательство John Wiley & Sons Limited
This book provides a comprehensive and up-to-date coverage of the relationship between drug metabolism enzymes and transporters on drug toxicity, along with methods to investigate their role on adverse drug reactions. Unites both the metabolism and transporter components of drug toxicity – two aspects not normally connected and the latter often neglected Familiarizes readers with the mechanism and species differences in drug metabolizing enzymes and transporters Discusses promising approaches to accurately predict human drug toxicity via the incorporation of human drug metabolism in toxicity evaluation