Phosphodiesterases and Their Inhibitors. Hugo Kubinyi

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Phosphodiesterases and Their Inhibitors


Год выпуска 0

isbn 9783527682355

Автор произведения Hugo Kubinyi

Жанр Медицина

Серия

Издательство John Wiley & Sons Limited


Written by the pioneers of Viagra, the first blockbuster PDE inhibitor drug. Beginning with a review of the first wave of phosphodiesterase (PDE) inhibitors, this book focuses on new and emerging PDE targets and their inhibitors. Drug development options for all major human PDE families are discussed and cover diverse therapeutic fields, such as neurological/psychiatric, cardiovascular/metabolic, pain, and allergy/respiratory diseases. Finally, emerging chemotherapeutic applications of PDE inhibitors against malaria and other tropical diseases are discussed.