Группа авторов
Список книг автора Группа авторовClinical Manual of Anxiety Disorders
Anxiety disorders are among the most prevalent, persistent, disabling, and costly psychiatric disorders, yet they are often underdiagnosed and undertreated. Fortunately, there have been major advances in understanding and treating these conditions in recent years; this is one of the most exciting areas in modern medicine.This clinical manual has earned its place in the literature as one of just a few volumes that covers all of the major anxiety disorders and presents integrated contributions from both psychopharmacologists and psychotherapists – all in one compact work written for busy clinicians.Though concepts of anxiety have long enjoyed a central position in philosophical and psychoanalytic theories, empirical research on anxiety disorders has a relatively short history. Here, 16 experts discuss advances in diagnosis, assessment (including relevant rating scales), pharmacotherapy, and psychotherapy.This volume begins by reviewing recent important diagnostic, epidemiological, neurobiological, and treatment findings – all of which have significant implications for clinicians. Subsequent chapters cover Panic disorder and agoraphobia – Laboratory studies of fear have significantly advanced our understanding of the neurocircuitry and neurochemistry of panic. Furthermore, panic disorder is now readily treated with both medications and psychotherapy. Specific phobia – Viewed for many years as mild and even trivial, this common disorder is now recognized for its very real associated distress and impairment. Exposure therapy is the treatment mainstay, though pharmacotherapy should be considered particularly when there is comorbidity. Social phobia (or social anxiety disorder) – In the past few years, the first FDA-approved medications for this disorder have been made available. Cognitive-behavioral therapy is also effective for the treatment of this underdiagnosed and undertreated condition. Obsessive-compulsive disorder (OCD) – OCD was the first disorder where it was shown that both specific medications and cognitive-behavioral techniques resulted in normalization of activity in particular brain structures. It is now possible to provide patients with integrated treatment approaches. Posttraumatic stress disorder (PTSD) – Once viewed as a normal reaction to trauma, PTSD is increasingly understood as a pathological response, characterized by specific psychobiological dysfunctions. Again, there have been exciting advances in the treatment of this disorder, with the release of the first FDA-approved agents for PTSD. Generalized anxiety disorder (GAD) – For a number of years GAD was thought of as a residual disorder occasionally seen in combination with more primary conditions. Nowadays, we know that GAD is an independent condition that is prevalent, persistent, and disabling. Busy residents and psychiatrists in active clinical practice, psychologists, primary care practitioners, and other mental health professionals will find this clinical manual – with its integrated approach of both pharmacotherapy and psychotherapy – a valuable tool in their everyday practices.
The American Psychiatric Publishing Textbook of Mood Disorders
Psychiatrists and other mental health care and medical professionals can now turn to a truly authoritative, up-to-date reference for current information about mood disorders. The American Psychiatric Publishing Textbook of Mood Disorders – including a wealth of illustrations, tables and references – presents the state of the art in diagnosis, psychobiology, pharmacotherapy, and psychotherapy across the vast spectrum of mood disorders: Symptomatology and Epidemiology: historical aspects and social underpinnings of mood disorders, classification and rating scales, and global burden Pathogenesis: neurochemistry and psychoneuroendocrinology, cognitive processing models (experimental cognitive research), and evolutionary explanations Methods of Investigation:anatomical pathology, molecular and cellular neurobiology of severe mood disorders, and genetics of bipolar and unipolar disorders Types of Mood Disorder: psychotic depression, seasonal affective disorder, secondary depression with medical illness, major depression seen in primary care, and substance abuse, and sleep disorders Treatments: pharmacotherapy, brain stimulation techniques, and psychotherapies Pertinent Factors: personality, culture, and gender Offering a fascinating synthesis of the multifaceted field of mood disorders, the richly informative American Psychiatric Publishing Textbook of Mood Disorders will prove invaluable for psychiatric and medical practitioners, educators, students, and residents interested in the latest breakthroughs in the diagnosis, treatment, and management of mood disorders.
Traumatic Dissociation
Traumatic Dissociation: Neurobiology and Treatment offers an advanced introduction to this symptom, process, and pattern of personality organization seen in several trauma-related disorders, including acute stress disorder, posttraumatic stress disorder (PTSD), and the dissociative disorders. Our understanding of traumatic dissociation has recently been advanced by neuroimaging technology, empirically-based investigation, and an acknowledgment of its importance in psychopathology. The authors of this volume tie these findings together, tracking the condition from its earliest historical conceptualization to its most recent neurobiological understanding to provide even greater insight into traumatic dissociation and its treatment.Bringing together for the first time theoretical, cognitive, and neurobiological perspectives on traumatic dissociation, this volume is designed to provide both empirical and therapeutic insights by drawing on the work of many of the main contributors to the field. Opening chapters examine historical, conceptual, and theoretical issues and how other fields, such as cognitive psychology, have been applied to the study of traumatic dissociation. The following section focuses specifically on how neurobiological investigations have deepened our understanding of dissociation and concluding chapters explore issues pertinent to the assessment and treatment of traumatic dissociation. The interacting effects of traumatic experience, developmental history, neurobiological function, and specific vulnerabilities to dissociative processes that underlie the occurrence of traumatic dissociation are among some of the key issues covered. The book's significant contributions include A review of cognitive experimental findings on attention and memory functioning in dissociative identity disorder An appreciation of how the literature on hypnosis provides a greater understanding of perceptual processing and traumatic stress Ascertaining symptoms of dissociation in a military setting and in other situations of extreme stress An outline of key issues for planning assessment of traumatic dissociation, including a critique of its primary empirically supported standardized measures An examination of the association between child abuse or neglect and the development of eating disorders, suggesting ways to therapeutically deal with negative body experience to reduce events that trigger dissociation A description of neuroendocrine alterations associated with stress, pointing toward a better understanding of the developmental effects of deprivation and trauma on PTSD and dissociation A review of the relation of attachment and dissociation A discussion of new research findings in the neuroimaging of dissociation and a link between cerebellar functioning and specific peritraumatic experiences Useful as a clinical reference or as ancillary textbook, Traumatic Dissociation reorganizes phenomenological observations that have been overlooked, misunderstood, or neglected in traditional training. The research and clinical experience described here will provide the basis for further clinical and theoretical formulations of traumatic dissociation and will advance empirical examination and treatment of the phenomenon.
Sleep Disorders and Psychiatry
Sleep and wakefulness are fundamental behavioral and neurobiological states that characterize all higher animals, including human beings. Concise yet comprehensive, Sleep Disorders and Psychiatry, the latest volume in American Psychiatric Publishing's popular Review of Psychiatry Series, presents the cumulative experience of 12 experts who talk about what sleep is and why sleep is essential to maintaining good health, summarizing the major categories of sleep disorders and detailing how virtually every psychiatric disorder and a wide variety of medical illnesses adversely affect sleep.Sleep Disorders and Psychiatry is the ideal companion to busy psychiatric clinicians because it is Comprehensive, covering all information of particular relevance to psychiatric clinicians. Enhanced by numerous tables and illustrations that make it easy to understand and reference while «on the go» during everyday practice. Clearly structured and easy to understand, with chapters organized according to the major categories of sleep disorders most likely to be encountered in psychiatric clinical practice. The fascinating introduction discusses the functions of sleep and the consequences of sleep deprivation, including the complex neurobiology of circadian rhythms, sleep and wakefulness, the clinical assessment and management of sleep and circadian rhythm disorders, and the pros and cons of tools for taking an accurate history. Each of the six subsequent chapters in Sleep Disorders and Psychiatry follows the same format by detailing the definitions and clinical description, epidemiology, etiology and pathogenesis, and treatment for a major category of sleep disorder: insomnia, sleep apnea, narcolepsy and syndromes of central nervous system-mediated sleepiness, restless legs syndrome, parasomnias, and circadian rhythm sleep disorders.Further, Sleep Disorders and Psychiatry provides psychiatrists with the tools necessary to embark upon exciting collaborations with specialists from other areas of clinical medicine (psychologists, pulmonologists, neurologists and surgeons). Given the importance of behavioral and psychopharmacologic interventions in managing sleep disorders, psychiatrists can often make valuable contributions to the care of medically ill patients with these conditions.Abundantly referenced and illustrated, Sleep Disorders and Psychiatry is the ultimate practical resource for busy clinicians interested in the broad and growing field of sleep disorders.
Research Advances in Genetics and Genomics
Research Advances in Genetics and Genomics: Implications for Psychiatry introduces mental health professionals to exciting breakthroughs in endophenotypes, animal models, microarrays, and genetic mapping, as well as general strategies for identifying the genetic mechanisms of mental illnesses.Uniquely valuable both as summary and signpost, this concise volume provides a fascinating overview of recent cutting-edge developments in the application of molecular genetics, genomics, and proteomics to the study of psychiatric populations. By reading Research Advances in Genetics and Genomics, you will gain a better understanding of Psychiatric Genetics – Reviews and assesses the major research paradigms that have emerged in the field of psychiatric genetics over the several past decades, exploring the major conceptual and philosophical issues they pose and the value of their integration. Molecular Structure of Nucleic Acids – An overview of the double-helix discovery and provides a context for current endeavors, the original one-page April 1953 Nature paper by Watson and Crick, which sparked a revolution in the life sciences. Psychiatry in the Genomics Era – Posits that one of the most important consequences of genomics will be the development of individualized treatments that allow a clinician to tailor therapy on the basis of the unique genotype of each patient rather than on the mean responses of groups of unrelated patients. The Genomics Revolution – Details the implications of the genome for future medical practice, including the potential for developing methods and tools to better understand, treat, and prevent major mental disorders. The Endophenotype Concept in Psychiatry – Explains the etymology and strategy behind the use of endophenotypes in neuropsychiatric research and, more generally, in research on other diseases with complex genetics, such as schizophrenia. The Genes and Brains of Mice and Men – Shows why a detailed assessment of brain function in mice is so important for advancing psychiatric research in humans. Humans and mice share numerous features-in fact, for an estimated 99% of human genes a mouse version may be identified-of brain organization and behavioral responses to many pharmacological agents. Microarray Technology – Asserts that microarrays present a methodology for identifying genes or pathways for new and unique potential drug targets, determining premorbid diagnosis, predicting drug responsiveness for individual patients, and, eventually, initiating gene therapy and prevention strategies. Meticulously referenced, this volume is exceptionally useful as a starting point for understanding the impact of genetics and genomics on psychiatry, serving to introduce psychiatrists, psychologists, neurologists, and geneticists to this exciting field.
Relational Processes and DSM-V
Seeking to integrate the large volume of clinical research on relational processes and mental health disorders with other scientific advances in psychiatry, Relational Processes and DSM-V builds on exciting advances in clinical research on troubled relationships. These advances included marked improvements in the assessment and epidemiology of troubled relationships as well the use of genetics, neuroscience, and immunology to explore the importance of close relationships in clinical practice. Advances in family-based intervention, and prevention are also highlighted to help practitioners and researchers find common ground and begin an empirically based discussion about the best way to revise the DSM. Given the overwhelming research showing that relationships play a role in regulating neurobiology and genetic expression and are critical for understanding schizophrenia, conduct disorder, and depression among other disorders, relational processes must be a part of any empirically based plan for revising psychiatric nosology in DSM-V. The chapters in this book counter the perspective that we can safely discard the biopsychosocial model that has guided psychiatry in the past. The contributors examine the relevance of close relationships in such issues as the basic psychopathology of mental disorders, factors influencing maintenance and relapse, sources of burden for family members, and guiding family-based interventions. By tying relational processes to basic research on psychopathology, they demonstrate the value of integrating basic behavioral and brain research with a sophisticated understanding of the self-organizing and self-sustaining characteristics of relationships. Coverage includes: research linking relational processes to neuroscience, neurobiology, health outcomes, intervention research, prevention research, and genetics consideration of specific circumstances, such as promoting healthy parenting following divorce and relational processes in depressed Latino adolescents optimal approaches to the assessment of relational processes with clinical significance, such as child abuse, partner abuse, and expressed emotion. a simple introduction to the methodology of taxometrics, offering insight into whether key relational processes are distinct categories or continuously distributed variables an overview of the links between relational processes and psychiatric outcomes, providing a theoretical foundation for the discussion of links to psychopathology Together, these contributions seek to develop a shared commitment among clinicians, researchers, and psychopathologists to take seriously the issue of relational processes as they relate to diagnoses within DSM-and to encourage mental health care workers at all levels to harness the generative and healing properties of intimate relationships and make them a focus of clinical practice. It is a book that will prove useful to all who are interested in integrating greater sensitivity to relational processes in their work.
Recognition and Prevention of Major Mental and Substance Use Disorders
Recognizing that favorable clinical outcomes are associated with earlier initiation of treatment – and even more ideally with prevention – this volume addresses the current status of early intervention in, and prevention of, major mental and substance use disorders. A team of distinguished participants addresses this problem at many levels – from the DNA molecule to public policy – in order to show how prevention efforts should be informed by a better understanding of etiology and by a knowledge of indicators of vulnerability.In considering the current standing of etiological knowledge, Recognition and Prevention of Major Mental and Substance Use Disorders addresses issues that are critical precursors to the prevention of mental disorders and offers an understanding of factors that contribute to the disorders' development. The contributors review genetic methodologies and current findings in mental disorders, with an emphasis on schizophrenia, and then show how biological and psychosocial environmental variables may affect vulnerability. Chapters devoted specifically to lessons in prevention drawn from recent research into schizophrenia discuss the implications of prodromal studies and relationships between stress, critical periods, and the development of the disorder. The book includes contributions from NIH representatives on how basic scientific understanding of mental disorders can be translated into public policy. It also features chapters that describe cutting-edge projects in prevention research for Alzheimer's disease, drug dependence, antisocial behavior, and posttraumatic stress disorder – each providing compelling accounts of how existing knowledge can be adapted to promising prevention efforts. Among the volume's contributions: New data on the role of substance abuse – particularly marijuana and psychostimulants – in increasing vulnerability to schizophrenia Review of vulnerability factors for several relevant disorders, examining stress and its concomitant psychobiological responses and the contribution of cognitive factors to vulnerability to depression Intriguing approach for translating successful treatment methods for schizophrenia into efforts to prevent the transition from the prodrome of the disorder to the full-blown illness Program for prevention of antisocial behavior that can be implemented as early as the first grade Secondary prevention efforts for posttraumatic stress disorder, with a focus on pharmacological interventions Each chapter reviews clinical implications of the research presented, contributing to a volume that will benefit clinicians and researchers who share the goal of preventing these debilitating conditions. This multidimensional, interdisciplinary work represents a major step toward cutting the social costs of these disorders – and, more important, their untold cost in human suffering.
Psychiatric Genetics
Psychiatric Genetics is a concise reference that presents the complexities of this dynamic field in a clearly written, easily accessible format, with numerous tables and illustrations. Ten expert contributors offer a fascinating view of psychiatric genetics in a text that is thorough and scholarly yet also succinct and accessible.The introduction summarizes the field's four distinct paradigms – and their interrelationships – that help us understand the role of genetic factors in the etiology of psychiatric disorders: basic genetic epidemiology, which demonstrates heritability; advanced genetic epidemiology, which explores the nature and mode of action of these genetic risk factors; gene finding, which enables us to infer the probability that a locus in the genomic region under investigation contributes to psychiatric disorder liability; and molecular genetics, which traces the biological mechanisms by which the DNA variant identified using gene finding methods contributes to the disorder itself.Psychiatric Genetics illustrates the importance of Appreciating the complex field of psychiatric genetics – Presents the major conceptual and statistical issues in psychiatric genetics, including many of the basic principles of both genetic epidemiology and gene finding, as well as a brief review of DNA itself. Detailing the results for one disorder where substantial progress had been made in gene finding and molecular genetics – Covers schizophrenia, because of the substantial progress made during the past few years. Presenting results for a more typical and common set of psychiatric disorders where most of our information comes from basic and advanced genetic epidemiology and where we are just beginning to make advances using gene finding – Discusses anxiety disorders, which illustrate these sets of issues. Covering disorders where major advances have been made using basic and advanced genetic epidemiology – Details substance use disorders, where the paradigm has shifted from sociological to genetic factors and where, in contrast to the genetics of more traditional psychiatric disorders, researchers must consider the inherent conditionality of drug abuse. Investigating the role of genetics in personality disorders – Focuses on the development of conduct and antisocial behavior and how to incorporate developmental processes into analyses of the role of genetics. Psychiatric Genetics draws students, educators, and practitioners alike into the exciting world of psychiatric genetics with a lively discussion of its broad trends and of the strengths and limitations of its methods to provide true insight into the etiology of psychiatric and substance use disorders.
Mood and Anxiety Disorders During Pregnancy and Postpartum
Mood and Anxiety Disorders During Pregnancy and Postpartum earns its important place in the literature by detailing our current understanding of the course, diagnosis, and treatment of psychiatric illness during pregnancy and postpartum, including breast-feeding – a top priority today because we now know that active maternal psychiatric illness during pregnancy and postpartum can exert long-term negative effects on child development and cause significant morbidity for the mother.In just five concise richly informative chapters, the nine distinguished contributors to Mood and Anxiety Disorders During Pregnancy and Postpartum dispel prevailing beliefs and offer invaluable guidance in treating women during pregnancy and postpartum: Course of Psychiatric Illness During Pregnancy and the Postpartum Period – Despite the enduring belief that pregnancy is a time of emotional well-being for women, emerging data show that pregnancy is instead a time of increased vulnerability to psychiatric illness. Diagnosis and Treatment of Mood and Anxiety Disorders During Pregnancy – Though the use of psychotropic medications during pregnancy and postpartum raises concerns, the accumulating data support the use of certain SSRIs/tricyclic antidepressants, especially when balanced against the risk to both mother and child of depression during pregnancy. Management of Bipolar Disorder During Pregnancy and the Postpartum Period: Weighing the Risks and Benefits – Although the onset of bipolar disorder (BP) tends to occur during women's reproductive years, surprisingly little is known about the impact of the menstrual cycle, pregnancy, postpartum, breast-feeding, and menopause on the course and treatment of bipolar disorder. Postpartum Mood Disorders – Women experience a dramatic increase in their risk of developing severe psychiatric illness during postpartum for a full year after delivery. Often overlooked, postpartum disorders must be identified and treated as early as possible to reduce the mother's risk for recurrent and treatment-refractory illness and the child's risk for long-term development problems due to the detrimental effect of maternal depression. Use of Antidepressants and Mood Stabilizers in Breast-feeding Women – This expanded clinical appraisal of the literature on antidepressant and mood stabilizer use in breast-feeding women shows that additional detailed pharmacokinetic investigations are urgently needed to enhance our understanding of nursing infant exposure and the role(s) of pharmacogenomics in determining infant exposure. Meticulously referenced and remarkably succinct, Mood and Anxiety Disorders During Pregnancy and Postpartum provides critical information about the course of illness during pregnancy and postpartum to help guide effective individualized treatment decisions-decisions that are ultimately based on the patient's wishes.
Medical and Psychiatric Comorbidity Over the Course of Life
Compiled from presentations given at the 2004 American Psychopathological Association (APPA) annual meeting, Medical and Psychiatric Comorbidity Over the Course of Life reviews the comorbidity of mental and chronic physical syndromes in an epidemiological and life course context, offering fresh insights and identifying crucial clues – gleaned from the overlapping areas or areas of mutual pathogenesis linking disparate realms of knowledge – to the etiology and nosological distinctiveness of both physical and mental disorders.Once relatively ignored, the study of lifetime comorbidity has the potential to suggest etiological clues and to advance our ability to prevent secondary disorders by increasing our knowledge about the course and pathology of the primary disease. The etiologically relevant period, beginning with the earliest causal action and ending with diagnosis, helps us understand this potential and thus is vital to the study of comorbidity. Divided into five main sections (epidemiology, risk factors, mood disorders, emotions and health, and schizophrenia), Medical and Psychiatric Comorbidity Over the Course of Life discusses critical aspects of the life course characteristics of the etiologically relevant period: It can be long, e.g., temperament, a relatively enduring emotional predisposition, may situate an individual more or less permanently at high risk, culminating in irreversibility only after decades of induction. The action of identical genes produces different disorders that may occur at different stages of life, such as the comorbidity of panic disorder and cystitis. It may involve critical stages, i.e., relatively narrow periods during development, such as fetal growth and puberty, to which the action of a given cause is limited. Critical periods of varying durations may exist throughout the course of life. It may have a cumulative quality to it, in which years or even decades of accumulation are required to reach the point of irreversibility, e.g., the years-long burden of lower class life, or of increased allostatic burden, for the causal nexus to reach sufficiency. It may involve multiple causes, representing different disciplines and different spheres of action spread throughout the life course. Medical and Psychiatric Comorbidity Over the Course of Life will prove invaluable for practitioners in general and consultation-liaison psychiatry, family practice and internal medicine, and psychosomatics, behavioral medicine, and health psychology.