Reactions with metals are ubiquitous in organic synthesis and, particularly in the last few years, a large repertoire of methods for the activation of metals and for their use in organic synthesis has been developed. In Active Metals, topics ranging from morphology of metal clusters and nanometallurgy to organometallic chemistry, catalysis and the use of activated metals in natural product synthesis are authoritatively discussed by leading experts in the field. Active Metals will allow you to fully benefit from the recent advances in the field by giving: * Detailed experimental procedures * Guidance on manipulation of active metals under inert atmosphere * Valuable information for planning syntheses * Extensive tables of typical conversions with yields * Critically selected, up-to-date references This handbook is a unique source of 'hands-on' information which will allow you to expand the scope of your research.
When Wittig first developed and described phosphorus ylides, nobody could have imagined how useful and versatile this class of compounds could be. This book provides a comprehensive and up-to-date compilation of the chemistry and applications of phosphorus ylides in organic synthesis. The ylides are discussed as reagents in the synthesis of a broad range of substances, amongst them olefins, acetylenes, cyclic and heterocyclic compounds, in such naturally occurring compounds as pheromones, steroids and carotenoids, and pharmaceutically and biologically active compounds such as antibiotics and prostaglandins. A particularly beneficial feature of this book is the 150 key experimental procedures with all the necessary data, allowing the preparation to start immediately without the need for an extremely time-consuming literature search. But should a search prove inevitable, around 2,500 references provide easy access to the primary literature. Every chemist in academia and industry working in organic, bioorganic, inorganic, and medicinal chemistry will welcome this book as an inspiration of concepts, ideas and practical syntheses.
The story of success goes on and on – with a new book on combinatorial chemistry, edited by Gunther Jung! Combinatorial chemistry is a proven time- and resource-saving synthetic method of outstanding importance for industrial processes. Compound libraries help to save time and money, especially in the search for new drugs, and therefore play a pivotal role in solving the problem of the worldwide increasing demand for new and more active drugs. Not only substances, which are of interest for pharmaceutical chemistry, but also materials, catalysts, and biomolecules such as DNA or oligosaccharides are readily available with high structural diversities. The broad scope of combinatorial sciences is reflected by this book, edited by Gunther Jung: The synthetic methods discussed range from solid-phase to solution-phase synthesis, from preparations of small molecules such as amines or alcohols to those of complex biomolecules. Feasible methods, efficient techniques, new trends in automation, and state-of-the-art fast instrumental analytical and screening methods are presented with many practical tips and tricks for everybody working in combinatorial chemistry. This is the book written by specialists for specialists and for everyone aspiring to become an insider! It is an indispensible source of information for researchers working in organic synthesis, catalysis, biochemistry, and biotechnology, pharmaceutical and clinical chemistry, material sciences, and analytical chemistry.
For the first time, the whole field of organoboronic acids is presented in one comprehensive handbook. Professor Dennis Hall, a rising star within the community, covers all aspects of this important substance class, including applications in chemistry, biology and medicine. Starting with an introduction to the structure, properties, and preparation of boronic acid derivatives, together with an overview of their reactions and applications, the book goes on to look at metal-catalyzed borylation of alkanes and arenas, coupling reactions and rhodium-catalyzed additions of boronic acids to alkenes and carbonyl compounds. There follows chapters on copper-promoted C-O and C-N cross-coupling of boronic acids, recent applications in organic synthesis, as well as alpha-haloalkylboronic esters in asymmetric synthesis. Later sections deal with cycloadditions, organoboronic acids, oxazaborolidines as asymmetric inducers, and boronic acid based receptors and sensors. The whole is rounded off with experimental procedures, making this invaluable reading for organic, catalytic and medicinal chemists, as well as those working in organometallics.
This first book on this fascinating topic is edited by one of today's most famous and internationally respected organic chemists, renowned for his pioneering synthesis of the cyclopropenyl cation. For his part, Ronald Breslow has brought together leading scientists in this expanding area to provide a novel overview of protein-, cyclodextrin-, metal- and porphyrin-based artificial enzymes as well as enzyme-like polymers and dendrimers. A must for all scientists interested in this emerging field.
At long last: The second, completely revised edition of this comprehensive standard reference. Alwyn G. Davies has updated the contents of his book to reflect the current state of research into organotin chemistry. He covers all aspects in detail, such as its synthesis, characterization, structures and applications, while also devoting space to such hot topics as environmental issues. This new edition also includes a CD-ROM with more than 5,000 references, making this database an invaluable tool for everyone working in the field. «The text is well written, extremely accessible and very comprehensive: particularly impressive is the inclusion of up-to-the-minute references in these areas....» – Advanced Materials, 13 (1998) «The standard of production is very good, with well-structured tables and an abundance of clear formula schemas, which enable the reader to quickly grasp the essence of the text.» – Angewandte Chemie 16, 1997
A practical guide to wastewater bacteria and the roles they perform in wastewater treatment Communicating material in a practical manner for operators and technicians who regulate and troubleshoot their wastewater treatment processes, Wastewater Bacteria discusses the effective control and proper operation of aerobic (activated sludge) and anaerobic (anaerobic digesters) biological treatment units to ensure that an adequate, active, and appropriate population of bacteria is present in each treatment unit. It is a hands-on guide to understanding the biology and biological conditions that occur at each treatment unit. Avoiding unnecessary technical jargon and chemical equations, Wastewater Bacteria, the fifth book in the Wastewater Microbiology Series, explores and explains: * Bacteria and the wastewater environment * Enzymes and sludge production * Nitrogen, phosphorus, and sulfur bacteria * Floc formation and filamentous organisms * Nitrification and denitrification * Sulfate reduction, fermentation, and methane production * Toxicity * Foam and malodor production The goal of Wastewater Bacteria is to enable plant operators to achieve the twofold basic objectives of wastewater treatment-to degrade organic wastes to a level where a significant, dissolved oxygen demand is not exerted upon receiving waters and to remove nutrients to levels where photosynthetic organisms in receiving waters are limited in their growth. This straightforward manual equips plant technicians to meet these objectives with essential information to understand the biological processes and organisms involved in wastewater treatment.
Ideal for those who have previously studies organic chemistry but not in great depth and with little exposure to organic chemistry in a formal sense. This text aims to bridge the gap between introductory-level instruction and more advanced graduate-level texts, reviewing the basics as well as presenting the more advanced ideas that are currently of importance in organic chemistry. * Provides students with the organic chemistry background required to succeed in advanced courses. * Practice problems included at the end of each chapter.
Consolidates information and technical calculations for a wide variety of environmental factors Operating a business facility of any size, especially a manufacturing location, requires environmental permits from a number of governmental regulatory agencies responsible for protecting human health and the environment. Environmental Calculations: A Multimedia Approach provides an essential, one-stop reference for the necessary technical calculations to obtain a broad range of such permits. Along with clear, concise, and factual explanations, the text also includes relevant equations, examples, and case studies to support and clarify the calculations. Filled with the rich experience from the author's years of work in environmental permitting, the coverage features: An introduction to the major concepts and practice in the permitting process Key concepts in environmental chemistry such as the ideal gas law, vapor pressure, reaction stoichiometry, and heat effects Air pollution control Water/wastewater Solid/hazardous waste Noise generation, propagation, and control Radiation/radioactive decay An all-around guide for environmental permitting in many contexts, Environmental Calculations: A Multimedia Approach is a must-have for anybody concerned with environmental assessment and compliance, as well as those reviewing, issuing, and monitoring environmental permits.